JP2024544067A5 - - Google Patents
Info
- Publication number
- JP2024544067A5 JP2024544067A5 JP2024532266A JP2024532266A JP2024544067A5 JP 2024544067 A5 JP2024544067 A5 JP 2024544067A5 JP 2024532266 A JP2024532266 A JP 2024532266A JP 2024532266 A JP2024532266 A JP 2024532266A JP 2024544067 A5 JP2024544067 A5 JP 2024544067A5
- Authority
- JP
- Japan
- Prior art keywords
- chemically modified
- modified oligonucleotide
- oligonucleotide according
- bonds
- nucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21211372.4 | 2021-11-30 | ||
| EP21211372 | 2021-11-30 | ||
| PCT/EP2022/083711 WO2023099494A1 (en) | 2021-11-30 | 2022-11-29 | Antisense oligonucleotides (aso) for efficient and precise rna editing with endogenous adenosine deaminase acting on rna (adar) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024544067A JP2024544067A (ja) | 2024-11-27 |
| JP2024544067A5 true JP2024544067A5 (enExample) | 2025-12-11 |
Family
ID=78820190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024532266A Pending JP2024544067A (ja) | 2021-11-30 | 2022-11-29 | Ｒｎａに作用する内因性アデノシンデアミナーゼ（ａｄａｒ）による効率的および正確なｒｎａ編集のためのアンチセンスオリゴヌクレオチド（ａｓｏ） |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230235329A1 (enExample) |
| EP (1) | EP4441216A1 (enExample) |
| JP (1) | JP2024544067A (enExample) |
| KR (1) | KR20240111752A (enExample) |
| CN (1) | CN118355119A (enExample) |
| AU (1) | AU2022399905A1 (enExample) |
| CA (1) | CA3238033A1 (enExample) |
| IL (1) | IL312762A (enExample) |
| WO (1) | WO2023099494A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024114908A1 (en) * | 2022-11-30 | 2024-06-06 | Eberhard Karls Universität Tübingen | Chemically modified antisense oligonucleotides (asos) and compositions comprising the same for rna editing |
| CN121794378A (zh) * | 2023-08-15 | 2026-04-03 | 艾尔纳公司 | 用于rna编辑的化学修饰的反义寡核苷酸（aso）及组合物 |
| WO2025073902A1 (en) * | 2023-10-06 | 2025-04-10 | Eberhard Karls Universität Tübingen | Chemical and sequence optimisation of antisense oligonucleotides for adar-mediated rna editing |
| WO2025172372A1 (en) | 2024-02-12 | 2025-08-21 | Airna Corporation | Conjugate for targeted delivery of an antisense oligonucleotide |
| WO2025242018A1 (zh) * | 2024-05-20 | 2025-11-27 | 时夕(广州)生物科技有限公司 | 一种经修饰的向导agRNA |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110352244B (zh) * | 2016-09-01 | 2023-03-21 | ProQR治疗上市公司Ⅱ | 化学修饰的编辑rna的单链寡核苷酸 |
| JP7347830B2 (ja) | 2018-06-29 | 2023-09-20 | エバーハルト カール ウニヴェルジテート テュービンゲン | Ｒｎａ編集のための人工核酸 |
| CA3158528A1 (en) * | 2019-12-23 | 2021-07-01 | Jim SWILDENS | Antisense oligonucleotides for nucleotide deamination in the treatment of stargardt disease |
-
2022
- 2022-11-29 JP JP2024532266A patent/JP2024544067A/ja active Pending
- 2022-11-29 AU AU2022399905A patent/AU2022399905A1/en active Pending
- 2022-11-29 IL IL312762A patent/IL312762A/en unknown
- 2022-11-29 EP EP22823405.0A patent/EP4441216A1/en active Pending
- 2022-11-29 CA CA3238033A patent/CA3238033A1/en active Pending
- 2022-11-29 WO PCT/EP2022/083711 patent/WO2023099494A1/en not_active Ceased
- 2022-11-29 KR KR1020247016720A patent/KR20240111752A/ko active Pending
- 2022-11-29 CN CN202280079432.9A patent/CN118355119A/zh active Pending
- 2022-11-30 US US18/071,999 patent/US20230235329A1/en active Pending
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