JP2024545428A - 癌治療における患者選択のためのｃｅａアッセイ - Google Patents

癌治療における患者選択のためのｃｅａアッセイ Download PDF

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JP2024545428A
JP2024545428A JP2024532763A JP2024532763A JP2024545428A JP 2024545428 A JP2024545428 A JP 2024545428A JP 2024532763 A JP2024532763 A JP 2024532763A JP 2024532763 A JP2024532763 A JP 2024532763A JP 2024545428 A JP2024545428 A JP 2024545428A
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certain embodiments
cancer
antibody
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cea
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JP2024545428A5 (https=
Inventor
ムスタファ・シャドジャ
アンヌ－ロール・ボーシェ
セシル・コンボー
クリストフ・アンリ
ブリジット・デュメー
サミラ・ベンスフィア
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Sanofi SA
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Sanofi SA
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    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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  • Immunology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • General Physics & Mathematics (AREA)
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  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Inorganic Chemistry (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2024532763A 2021-12-02 2022-12-01 癌治療における患者選択のためのｃｅａアッセイ Pending JP2024545428A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP21306692.1 2021-12-02
EP21306692 2021-12-02
US202263385375P 2022-11-29 2022-11-29
US63/385,375 2022-11-29
PCT/EP2022/084107 WO2023099683A1 (en) 2021-12-02 2022-12-01 Cea assay for patient selection in cancer therapy

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JP2024545428A true JP2024545428A (ja) 2024-12-06
JP2024545428A5 JP2024545428A5 (https=) 2025-12-09

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US (1) US20250041434A1 (https=)
EP (1) EP4440603A1 (https=)
JP (1) JP2024545428A (https=)
KR (1) KR20240112348A (https=)
AU (1) AU2022400237A1 (https=)
CA (1) CA3239856A1 (https=)
IL (1) IL313224A (https=)
MX (1) MX2024006766A (https=)
TW (1) TW202339804A (https=)
WO (1) WO2023099683A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3199552T3 (da) * 2012-11-20 2020-03-30 Sanofi Sa Anti-ceacam5-antistoffer og anvendelser heraf
TWI851577B (zh) 2018-06-07 2024-08-11 美商思進公司 喜樹鹼結合物
AU2021379882A1 (en) 2020-11-10 2023-06-29 Sanofi Ceacam5 antibody-drug conjugate formulation
EP4427763A1 (en) * 2023-03-06 2024-09-11 Sanofi Antitumor combinations containing anti-ceacam5 antibody-drug conjugates, anti-vegfr-2 antibodies and anti-pd1/pd-l1 antibodies
KR20250169564A (ko) * 2023-03-23 2025-12-03 사노피 암 치료법에서 환자 선택을 위한 CEACAM5 mRNA 검정
WO2025169012A1 (en) 2024-02-06 2025-08-14 Sanofi Methods of treating ceacam5-expressing cancers

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