JP2024545052A5 - - Google Patents

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Publication number
JP2024545052A5
JP2024545052A5 JP2024532968A JP2024532968A JP2024545052A5 JP 2024545052 A5 JP2024545052 A5 JP 2024545052A5 JP 2024532968 A JP2024532968 A JP 2024532968A JP 2024532968 A JP2024532968 A JP 2024532968A JP 2024545052 A5 JP2024545052 A5 JP 2024545052A5
Authority
JP
Japan
Prior art keywords
represented
oligonucleotide
compound
equation
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024532968A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024545052A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/051740 external-priority patent/WO2023102242A2/en
Publication of JP2024545052A publication Critical patent/JP2024545052A/ja
Publication of JP2024545052A5 publication Critical patent/JP2024545052A5/ja
Pending legal-status Critical Current

Links

JP2024532968A 2021-12-03 2022-12-02 修飾骨格化学を有するスプライススイッチャーアンチセンスオリゴヌクレオチド Pending JP2024545052A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US202163285628P 2021-12-03 2021-12-03
US202163285786P 2021-12-03 2021-12-03
US202163285933P 2021-12-03 2021-12-03
US202163285631P 2021-12-03 2021-12-03
US63/285,786 2021-12-03
US63/285,628 2021-12-03
US63/285,631 2021-12-03
US63/285,933 2021-12-03
US202263350206P 2022-06-08 2022-06-08
US63/350,206 2022-06-08
US202263398992P 2022-08-18 2022-08-18
US202263398987P 2022-08-18 2022-08-18
US63/398,987 2022-08-18
US63/398,992 2022-08-18
PCT/US2022/051740 WO2023102242A2 (en) 2021-12-03 2022-12-02 Splice switcher antisense oligonucleotides with modified backbone chemistries

Publications (2)

Publication Number Publication Date
JP2024545052A JP2024545052A (ja) 2024-12-05
JP2024545052A5 true JP2024545052A5 (https=) 2026-01-19

Family

ID=86613046

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024532968A Pending JP2024545052A (ja) 2021-12-03 2022-12-02 修飾骨格化学を有するスプライススイッチャーアンチセンスオリゴヌクレオチド

Country Status (9)

Country Link
EP (1) EP4441226A2 (https=)
JP (1) JP2024545052A (https=)
KR (1) KR20240129626A9 (https=)
CN (1) CN119522282A (https=)
AU (1) AU2022402929A1 (https=)
CA (1) CA3241870A1 (https=)
IL (1) IL313141A (https=)
MX (1) MX2024006612A (https=)
WO (1) WO2023102242A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023356317A1 (en) * 2022-10-05 2025-05-15 Trace Neuroscience, Inc. Unc13a antisense oligonucleotides and uses thereof
WO2024178223A1 (en) * 2023-02-24 2024-08-29 Northwestern University Antisense oligonucleotides for preventing unc13a misplicing
GB202315883D0 (en) * 2023-10-17 2023-11-29 Univ Oxford Innovation Ltd Method
US12612630B2 (en) 2024-03-05 2026-04-28 Takeda Pharmaceutical Company Limited Compositions and methods for splicing modulation of UNC13A

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040063658A1 (en) * 2002-05-06 2004-04-01 Roberts Christopher Don Nucleoside derivatives for treating hepatitis C virus infection
CA2817256A1 (en) * 2010-11-12 2012-05-18 The General Hospital Corporation Polycomb-associated non-coding rnas
CA3126918A1 (en) * 2019-01-14 2020-07-23 President And Fellows Of Harvard College Methods and compositions for restoring stmn2 levels
EP3976010A4 (en) * 2019-06-03 2023-08-02 Quralis Corporation Oligonucleotides and methods of use for treating neurological diseases

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