JP2024545052A - 修飾骨格化学を有するスプライススイッチャーアンチセンスオリゴヌクレオチド - Google Patents

修飾骨格化学を有するスプライススイッチャーアンチセンスオリゴヌクレオチド Download PDF

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JP2024545052A
JP2024545052A JP2024532968A JP2024532968A JP2024545052A JP 2024545052 A JP2024545052 A JP 2024545052A JP 2024532968 A JP2024532968 A JP 2024532968A JP 2024532968 A JP2024532968 A JP 2024532968A JP 2024545052 A JP2024545052 A JP 2024545052A
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ヒンクリー，サンドラ
ブラウン，ダンカン
エルバウム，ダニエル
エリザベス カメルガーン，マリサ
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クラリス コーポレーション
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JP2024532968A 2021-12-03 2022-12-02 修飾骨格化学を有するスプライススイッチャーアンチセンスオリゴヌクレオチド Pending JP2024545052A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US202163285628P 2021-12-03 2021-12-03
US202163285933P 2021-12-03 2021-12-03
US202163285786P 2021-12-03 2021-12-03
US202163285631P 2021-12-03 2021-12-03
US63/285,631 2021-12-03
US63/285,933 2021-12-03
US63/285,786 2021-12-03
US63/285,628 2021-12-03
US202263350206P 2022-06-08 2022-06-08
US63/350,206 2022-06-08
US202263398987P 2022-08-18 2022-08-18
US202263398992P 2022-08-18 2022-08-18
US63/398,992 2022-08-18
US63/398,987 2022-08-18
PCT/US2022/051740 WO2023102242A2 (en) 2021-12-03 2022-12-02 Splice switcher antisense oligonucleotides with modified backbone chemistries

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JP2024545052A true JP2024545052A (ja) 2024-12-05
JP2024545052A5 JP2024545052A5 (https=) 2026-01-19
JPWO2023102242A5 JPWO2023102242A5 (https=) 2026-01-19

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EP (1) EP4441226A2 (https=)
JP (1) JP2024545052A (https=)
KR (1) KR20240129626A9 (https=)
CN (1) CN119522282A (https=)
AU (1) AU2022402929A1 (https=)
CA (1) CA3241870A1 (https=)
IL (1) IL313141A (https=)
MX (1) MX2024006612A (https=)
WO (1) WO2023102242A2 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023356317A1 (en) * 2022-10-05 2025-05-15 Trace Neuroscience, Inc. Unc13a antisense oligonucleotides and uses thereof
WO2024178223A1 (en) * 2023-02-24 2024-08-29 Northwestern University Antisense oligonucleotides for preventing unc13a misplicing
GB202315883D0 (en) * 2023-10-17 2023-11-29 Univ Oxford Innovation Ltd Method
WO2025186619A1 (en) * 2024-03-05 2025-09-12 Takeda Pharmaceutical Company Limited Compositions and methods for splicing modulation of unc13a

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003232071A1 (en) * 2002-05-06 2003-11-17 Genelabs Technologies, Inc. Nucleoside derivatives for treating hepatitis c virus infection
EP3260540A1 (en) * 2010-11-12 2017-12-27 The General Hospital Corporation Polycomb-associated non-coding rnas
WO2020150290A2 (en) * 2019-01-14 2020-07-23 President And Fellows Of Harvard College Methods and compositions for restoring stmn2 levels
JP7795914B2 (ja) * 2019-06-03 2026-01-08 クラリス コーポレーション 神経学的疾患を処置するためのオリゴヌクレオチドおよびその使用方法

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EP4441226A2 (en) 2024-10-09
IL313141A (en) 2024-07-01
WO2023102242A2 (en) 2023-06-08
KR20240129626A9 (ko) 2025-12-10
AU2022402929A1 (en) 2024-06-13
CA3241870A1 (en) 2023-06-08
MX2024006612A (es) 2024-06-12
WO2023102242A3 (en) 2023-10-12
WO2023102242A9 (en) 2024-10-31
KR20240129626A (ko) 2024-08-27
CN119522282A (zh) 2025-02-25

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