JP2024543214A5 - - Google Patents

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Publication number
JP2024543214A5
JP2024543214A5 JP2024532831A JP2024532831A JP2024543214A5 JP 2024543214 A5 JP2024543214 A5 JP 2024543214A5 JP 2024532831 A JP2024532831 A JP 2024532831A JP 2024532831 A JP2024532831 A JP 2024532831A JP 2024543214 A5 JP2024543214 A5 JP 2024543214A5
Authority
JP
Japan
Application number
JP2024532831A
Other languages
Japanese (ja)
Other versions
JPWO2023102225A5 (https=
JP2024543214A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/051713 external-priority patent/WO2023102225A2/en
Publication of JP2024543214A publication Critical patent/JP2024543214A/ja
Publication of JP2024543214A5 publication Critical patent/JP2024543214A5/ja
Publication of JPWO2023102225A5 publication Critical patent/JPWO2023102225A5/ja
Pending legal-status Critical Current

Links

JP2024532831A 2021-12-03 2022-12-02 Unc13a遺伝子転写物のモジュレーターを使用する神経疾患の処置 Pending JP2024543214A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163285786P 2021-12-03 2021-12-03
US63/285,786 2021-12-03
US202263350206P 2022-06-08 2022-06-08
US63/350,206 2022-06-08
US202263398987P 2022-08-18 2022-08-18
US63/398,987 2022-08-18
PCT/US2022/051713 WO2023102225A2 (en) 2021-12-03 2022-12-02 Treatment of neurological diseases using modulators of unc13a gene transcripts

Publications (3)

Publication Number Publication Date
JP2024543214A JP2024543214A (ja) 2024-11-19
JP2024543214A5 true JP2024543214A5 (https=) 2025-12-10
JPWO2023102225A5 JPWO2023102225A5 (https=) 2025-12-10

Family

ID=86613080

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024532831A Pending JP2024543214A (ja) 2021-12-03 2022-12-02 Unc13a遺伝子転写物のモジュレーターを使用する神経疾患の処置

Country Status (16)

Country Link
US (1) US20250051766A1 (https=)
EP (1) EP4441225A4 (https=)
JP (1) JP2024543214A (https=)
KR (1) KR20240129627A9 (https=)
CN (1) CN119790152A (https=)
AU (1) AU2022400851A1 (https=)
CA (1) CA3239482A1 (https=)
CL (1) CL2024001657A1 (https=)
CO (1) CO2024008076A2 (https=)
CR (1) CR20240269A (https=)
DO (1) DOP2024000107A (https=)
IL (1) IL313203A (https=)
JO (1) JOP20240125A1 (https=)
MX (1) MX2024006763A (https=)
PE (1) PE20250677A1 (https=)
WO (1) WO2023102225A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2603454A (en) 2020-12-09 2022-08-10 Ucl Business Ltd Novel therapeutics for the treatment of neurodegenerative disorders
AU2023356317A1 (en) * 2022-10-05 2025-05-15 Trace Neuroscience, Inc. Unc13a antisense oligonucleotides and uses thereof
WO2024178223A1 (en) * 2023-02-24 2024-08-29 Northwestern University Antisense oligonucleotides for preventing unc13a misplicing
WO2025186619A1 (en) * 2024-03-05 2025-09-12 Takeda Pharmaceutical Company Limited Compositions and methods for splicing modulation of unc13a
WO2025255388A1 (en) * 2024-06-05 2025-12-11 Camp4 Therapeutics Corporation Modulation of syngap1 gene transcription using antisense oligonucleotides targeting regulatory rnas
WO2026080323A1 (en) 2024-10-09 2026-04-16 Quralis Corporation Treatment of neurological diseases using modulators of unc13a gene transcripts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060008800A1 (en) * 2001-11-05 2006-01-12 Christian Rosenmund Unc-13 in the modulation of neurotransmission and secretion events
AU2013203395A1 (en) * 2012-03-30 2013-10-17 Isis Pharmaceuticals, Inc. Compositions and methods for modulating TAU expression for reducing seizure and modifying a neurodegenerative syndrome
DK3155101T3 (da) * 2014-06-16 2020-05-04 Univ Johns Hopkins Sammensætninger og fremgangsmåder til ekspression af CRISPR-leder-RNA´er under anvendelse af H1-promotoren
WO2020102472A1 (en) * 2018-11-15 2020-05-22 President And Fellows Of Harvard College Methods and compositions related to targeting ffar2 and ilc3 populations for the treatment of a gastrointestinal disease
AU2022255175A1 (en) * 2021-04-06 2023-11-23 Trace Neuroscience, Inc. Compositions and methods for treating tdp-43 proteinopathy

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