JP2025500335A5 - - Google Patents

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Publication number
JP2025500335A5
JP2025500335A5 JP2024537335A JP2024537335A JP2025500335A5 JP 2025500335 A5 JP2025500335 A5 JP 2025500335A5 JP 2024537335 A JP2024537335 A JP 2024537335A JP 2024537335 A JP2024537335 A JP 2024537335A JP 2025500335 A5 JP2025500335 A5 JP 2025500335A5
Authority
JP
Japan
Prior art keywords
sequence number
sequence
seq
antisense oligonucleotide
nos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024537335A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025500335A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/086915 external-priority patent/WO2023118087A1/en
Publication of JP2025500335A publication Critical patent/JP2025500335A/ja
Publication of JP2025500335A5 publication Critical patent/JP2025500335A5/ja
Pending legal-status Critical Current

Links

JP2024537335A 2021-12-21 2022-12-20 Unc13aを標的とするアンチセンスオリゴヌクレオチド Pending JP2025500335A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21216561 2021-12-21
EP21216561.7 2021-12-21
PCT/EP2022/086915 WO2023118087A1 (en) 2021-12-21 2022-12-20 Antisense oligonucleotides targeting unc13a

Publications (2)

Publication Number Publication Date
JP2025500335A JP2025500335A (ja) 2025-01-09
JP2025500335A5 true JP2025500335A5 (https=) 2026-01-06

Family

ID=79018929

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024537335A Pending JP2025500335A (ja) 2021-12-21 2022-12-20 Unc13aを標的とするアンチセンスオリゴヌクレオチド

Country Status (5)

Country Link
US (1) US20240327845A1 (https=)
EP (1) EP4453207A1 (https=)
JP (1) JP2025500335A (https=)
CN (1) CN118974254A (https=)
WO (1) WO2023118087A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2603454A (en) 2020-12-09 2022-08-10 Ucl Business Ltd Novel therapeutics for the treatment of neurodegenerative disorders
WO2023004049A1 (en) 2021-07-21 2023-01-26 AcuraStem, Inc. Unc13a antisense oligonucleotides
AU2023356317A1 (en) * 2022-10-05 2025-05-15 Trace Neuroscience, Inc. Unc13a antisense oligonucleotides and uses thereof
WO2025068363A1 (en) * 2023-09-29 2025-04-03 F. Hoffmann-La Roche Ag Peptide biomarker
US12612630B2 (en) 2024-03-05 2026-04-28 Takeda Pharmaceutical Company Limited Compositions and methods for splicing modulation of UNC13A

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2850183A4 (en) * 2012-05-16 2016-02-10 Rana Therapeutics Inc COMPOSITIONS AND METHOD FOR MODULATING GENE EXPRESSION
JP2023534557A (ja) * 2020-07-23 2023-08-09 エフ. ホフマン-ラ ロシュ アーゲー Rna結合タンパク質部位を標的とするオリゴヌクレオチド
GB2603454A (en) * 2020-12-09 2022-08-10 Ucl Business Ltd Novel therapeutics for the treatment of neurodegenerative disorders
EP4320236A1 (en) * 2021-04-06 2024-02-14 Maze Therapeutics, Inc. Compositions and methods for treating tdp-43 proteinopathy
EP4341406A4 (en) * 2021-05-21 2026-03-25 Ionis Pharmaceuticals Inc COMPOUNDS FOR MODULATING THE EXPRESSION OF UNC13A
WO2023004049A1 (en) * 2021-07-21 2023-01-26 AcuraStem, Inc. Unc13a antisense oligonucleotides

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