JP2025500335A5 - - Google Patents
Info
- Publication number
- JP2025500335A5 JP2025500335A5 JP2024537335A JP2024537335A JP2025500335A5 JP 2025500335 A5 JP2025500335 A5 JP 2025500335A5 JP 2024537335 A JP2024537335 A JP 2024537335A JP 2024537335 A JP2024537335 A JP 2024537335A JP 2025500335 A5 JP2025500335 A5 JP 2025500335A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence number
- sequence
- seq
- antisense oligonucleotide
- nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21216561 | 2021-12-21 | ||
| EP21216561.7 | 2021-12-21 | ||
| PCT/EP2022/086915 WO2023118087A1 (en) | 2021-12-21 | 2022-12-20 | Antisense oligonucleotides targeting unc13a |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025500335A JP2025500335A (ja) | 2025-01-09 |
| JP2025500335A5 true JP2025500335A5 (https=) | 2026-01-06 |
Family
ID=79018929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024537335A Pending JP2025500335A (ja) | 2021-12-21 | 2022-12-20 | Unc13aを標的とするアンチセンスオリゴヌクレオチド |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240327845A1 (https=) |
| EP (1) | EP4453207A1 (https=) |
| JP (1) | JP2025500335A (https=) |
| CN (1) | CN118974254A (https=) |
| WO (1) | WO2023118087A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2603454A (en) | 2020-12-09 | 2022-08-10 | Ucl Business Ltd | Novel therapeutics for the treatment of neurodegenerative disorders |
| WO2023004049A1 (en) | 2021-07-21 | 2023-01-26 | AcuraStem, Inc. | Unc13a antisense oligonucleotides |
| AU2023356317A1 (en) * | 2022-10-05 | 2025-05-15 | Trace Neuroscience, Inc. | Unc13a antisense oligonucleotides and uses thereof |
| WO2025068363A1 (en) * | 2023-09-29 | 2025-04-03 | F. Hoffmann-La Roche Ag | Peptide biomarker |
| US12612630B2 (en) | 2024-03-05 | 2026-04-28 | Takeda Pharmaceutical Company Limited | Compositions and methods for splicing modulation of UNC13A |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2850183A4 (en) * | 2012-05-16 | 2016-02-10 | Rana Therapeutics Inc | COMPOSITIONS AND METHOD FOR MODULATING GENE EXPRESSION |
| JP2023534557A (ja) * | 2020-07-23 | 2023-08-09 | エフ. ホフマン-ラ ロシュ アーゲー | Rna結合タンパク質部位を標的とするオリゴヌクレオチド |
| GB2603454A (en) * | 2020-12-09 | 2022-08-10 | Ucl Business Ltd | Novel therapeutics for the treatment of neurodegenerative disorders |
| EP4320236A1 (en) * | 2021-04-06 | 2024-02-14 | Maze Therapeutics, Inc. | Compositions and methods for treating tdp-43 proteinopathy |
| EP4341406A4 (en) * | 2021-05-21 | 2026-03-25 | Ionis Pharmaceuticals Inc | COMPOUNDS FOR MODULATING THE EXPRESSION OF UNC13A |
| WO2023004049A1 (en) * | 2021-07-21 | 2023-01-26 | AcuraStem, Inc. | Unc13a antisense oligonucleotides |
-
2022
- 2022-12-20 JP JP2024537335A patent/JP2025500335A/ja active Pending
- 2022-12-20 CN CN202280083648.2A patent/CN118974254A/zh active Pending
- 2022-12-20 WO PCT/EP2022/086915 patent/WO2023118087A1/en not_active Ceased
- 2022-12-20 EP EP22843158.1A patent/EP4453207A1/en active Pending
-
2024
- 2024-06-18 US US18/746,978 patent/US20240327845A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025500335A5 (https=) | ||
| US10369232B2 (en) | Allele selective gene editing and uses thereof | |
| JP2025501457A5 (https=) | ||
| US9157081B2 (en) | Chimeric oligomeric compounds for modulation of splicing | |
| CN110079525A (zh) | 反义核酸 | |
| JP2025500335A (ja) | Unc13aを標的とするアンチセンスオリゴヌクレオチド | |
| JP2025501457A (ja) | Actl6bを標的とするアンチセンスオリゴヌクレオチド | |
| TW202102676A (zh) | 調節atxn2表現之寡核苷酸 | |
| US20250051772A1 (en) | Antisense Oligonucleotide for Targeting Progranulin | |
| WO2022018155A1 (en) | Lna oligonucleotides for splice modulation of stmn2 | |
| CA3135794A1 (en) | Angptl2 antisense oligonucleotides and uses thereof | |
| US20220403388A1 (en) | Oligonucleotide Progranulin Agonists | |
| US20250188462A1 (en) | Antisense oligonucleotides for targeting progranulin | |
| US20230212572A1 (en) | Guanosine Analogues for Use in Therapeutics Polynucleotides | |
| HK40111667A (zh) | 靶向unc13a的反义寡核苷酸 | |
| HK40106800A (zh) | 靶向actl6b的反义寡核苷酸 | |
| HK40113673A (zh) | 反义寡核苷酸 | |
| JP2024505583A (ja) | Rtel1発現を阻害するための増強されたオリゴヌクレオチド | |
| WO2024126654A1 (en) | Antisense oligonucleotides targeting actl6b | |
| HK40111119A (zh) | 寡核苷酸gba激动剂 | |
| HK40114073A (zh) | 靶向cfp-elk1基因间区域的反义寡核苷酸 | |
| RU2024137893A (ru) | Улучшенные олигонуклеотиды, нацеленные на сайты рнк-связывающих белков | |
| HK40117040A (zh) | 靶向颗粒蛋白前体的反义寡核苷酸 | |
| WO2020038971A1 (en) | Antisense oligonucleotides targeting vcan |