JP2024542099A5 - - Google Patents

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Publication number
JP2024542099A5
JP2024542099A5 JP2024526594A JP2024526594A JP2024542099A5 JP 2024542099 A5 JP2024542099 A5 JP 2024542099A5 JP 2024526594 A JP2024526594 A JP 2024526594A JP 2024526594 A JP2024526594 A JP 2024526594A JP 2024542099 A5 JP2024542099 A5 JP 2024542099A5
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JP
Japan
Prior art keywords
approximately
mol
composition according
lipid
section
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024526594A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024542099A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/079244 external-priority patent/WO2023081776A1/en
Publication of JP2024542099A publication Critical patent/JP2024542099A/ja
Publication of JP2024542099A5 publication Critical patent/JP2024542099A5/ja
Pending legal-status Critical Current

Links

JP2024526594A 2021-11-03 2022-11-03 核酸を含む脂質調合物、及び嚢胞性線維症の治療方法 Pending JP2024542099A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163275402P 2021-11-03 2021-11-03
US63/275,402 2021-11-03
PCT/US2022/079244 WO2023081776A1 (en) 2021-11-03 2022-11-03 Lipid formulations containing nucleic acids and methods of treatment for cystic fibrosis

Publications (2)

Publication Number Publication Date
JP2024542099A JP2024542099A (ja) 2024-11-13
JP2024542099A5 true JP2024542099A5 (https=) 2025-11-12

Family

ID=86242208

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024526594A Pending JP2024542099A (ja) 2021-11-03 2022-11-03 核酸を含む脂質調合物、及び嚢胞性線維症の治療方法

Country Status (6)

Country Link
US (1) US20230159449A1 (https=)
EP (1) EP4426266A4 (https=)
JP (1) JP2024542099A (https=)
AU (1) AU2022381750A1 (https=)
CA (1) CA3236675A1 (https=)
WO (1) WO2023081776A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3176844A1 (en) * 2020-05-01 2021-11-04 Carlos G. PEREZ-GARCIA Nucleic acids and methods of treatment for cystic fibrosis
CZ310613B6 (cs) 2020-09-23 2026-01-28 Ústav organické chemie a biochemie AV ČR, v. v. i. Lipidoidy pro transfekci nukleových kyselin a jejich použití
CZ310443B6 (cs) 2021-07-19 2025-06-25 Ústav organické chemie a biochemie AV ČR, v. v. i. Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití
CN117653606B (zh) * 2023-11-14 2024-05-10 广东康百医药科技有限公司 一种间充质干细胞外泌体冻干保护剂及其应用
WO2025111297A1 (en) * 2023-11-21 2025-05-30 Modernatx, Inc. Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis
WO2025166325A1 (en) 2024-02-02 2025-08-07 Editas Medicine, Inc. MODIFIED GUIDE RNAs
WO2025213138A1 (en) 2024-04-05 2025-10-09 Editas Medicine, Inc. Crispr/rna-guided nuclease related methods and compositions for treating primary open angle glaucoma
WO2026003582A2 (en) 2024-06-27 2026-01-02 Axelyf ehf. Lipids and lipid nanoparticles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019013752A (es) * 2017-05-16 2020-07-20 Translate Bio Inc Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones.
ES3039647T3 (en) * 2017-05-31 2025-10-23 Arcturus Therapeutics Inc Synthesis and structure of high potency rna therapeutics
WO2019191780A1 (en) * 2018-03-30 2019-10-03 Arcturus Therapeutics, Inc. Lipid particles for nucleic acid delivery
KR20210091120A (ko) * 2018-08-29 2021-07-21 트랜슬레이트 바이오 인코포레이티드 Mrna-로딩된 지질 나노입자를 제조하는 개선된 공정
AU2021236068A1 (en) * 2020-03-09 2022-10-06 Arcturus Therapeutics, Inc. Compositions and methods for inducing immune responses

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