JP2024542021A5 - - Google Patents

Info

Publication number
JP2024542021A5
JP2024542021A5 JP2024525628A JP2024525628A JP2024542021A5 JP 2024542021 A5 JP2024542021 A5 JP 2024542021A5 JP 2024525628 A JP2024525628 A JP 2024525628A JP 2024525628 A JP2024525628 A JP 2024525628A JP 2024542021 A5 JP2024542021 A5 JP 2024542021A5
Authority
JP
Japan
Prior art keywords
alkyl
independently
aryl
case
haloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525628A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024542021A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/078995 external-priority patent/WO2023077129A1/en
Publication of JP2024542021A publication Critical patent/JP2024542021A/ja
Publication of JP2024542021A5 publication Critical patent/JP2024542021A5/ja
Pending legal-status Critical Current

Links

JP2024525628A 2021-10-29 2022-10-31 ペイロードのin vivo標的化送達用のテトラジンコンジュゲート Pending JP2024542021A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163273792P 2021-10-29 2021-10-29
US202163273785P 2021-10-29 2021-10-29
US63/273,792 2021-10-29
US63/273,785 2021-10-29
US202263315482P 2022-03-01 2022-03-01
US63/315,482 2022-03-01
US202263391136P 2022-07-21 2022-07-21
US63/391,136 2022-07-21
PCT/US2022/078995 WO2023077129A1 (en) 2021-10-29 2022-10-31 Tetrazine conjugates for in vivo targeted delivery of a payload

Publications (2)

Publication Number Publication Date
JP2024542021A JP2024542021A (ja) 2024-11-13
JP2024542021A5 true JP2024542021A5 (https=) 2025-11-11

Family

ID=84362765

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525628A Pending JP2024542021A (ja) 2021-10-29 2022-10-31 ペイロードのin vivo標的化送達用のテトラジンコンジュゲート

Country Status (4)

Country Link
US (1) US20250186592A1 (https=)
EP (1) EP4422696A1 (https=)
JP (1) JP2024542021A (https=)
WO (1) WO2023077129A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024178155A1 (en) * 2023-02-21 2024-08-29 Tambo, Inc. Trans-cyclooctene conjugates
KR20260046464A (ko) * 2023-07-27 2026-04-07 베락사 바이오테크 게엠베하 친수성 트랜스-시클로옥텐(hyTCO) 화합물, 이를 포함하는 구조체 및 접합체
WO2025059685A1 (en) * 2023-09-15 2025-03-20 Tambo, Inc. Methods for in vivo targeted delivery of a payload
WO2025260150A1 (en) * 2024-06-21 2025-12-26 Microbiológica Química E Farmacêutica Ltda. Novel n-benzyl phthalimides for the treatment of pain. methods of preparation and therapeutic use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR104E (https=)
KR20030057529A (ko) 2000-09-08 2003-07-04 그리폰 테라퓨틱스, 인코포레이티드 합성 적혈구생성 자극 단백질
ES2966631T3 (es) 2013-06-19 2024-04-23 Univ California Estructuras químicas para el suministro localizado de agentes terapéuticos
CN106659796B (zh) 2014-03-14 2021-04-30 加利福尼亚大学董事会 Tco缀合物和治疗剂递送方法
WO2017044983A1 (en) 2015-09-10 2017-03-16 Shasqi, Inc. Bioorthogonal compositions
WO2017106427A1 (en) * 2015-12-15 2017-06-22 Joseph Fox Methods for inducing bioorthogonal reactivity
AU2018250312C1 (en) 2017-04-07 2024-08-22 Tambo, Inc. Bioorthogonal compositions
SG11202103393XA (en) 2018-10-10 2021-04-29 Tambo Inc Processes for preparing functionalized cyclooctenes
WO2021007160A1 (en) 2019-07-05 2021-01-14 Tambo, Inc. Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
CN116056765A (zh) 2020-08-07 2023-05-02 坦伯公司 反式环辛烯生物正交剂及在癌症和免疫疗法中的用途

Similar Documents

Publication Publication Date Title
JP2024542021A5 (https=)
JP7644173B2 (ja) 単一分子量ポリサルコシンを含むリガンド-薬物-複合体
CA2650035C (en) Poly (ethylene glycol) containing chemically disparate endgroups
CN104530417B (zh) 一种多官能化h型聚乙二醇衍生物及其制备方法
KR102492135B1 (ko) 페길화된 카르필조밉 화합물
JP2025511899A (ja) イオン化可能なカチオン性脂質および脂質ナノ粒子
JP5349318B2 (ja) ステロイド類の高分子結合体
JP2010526183A5 (https=)
JP2010519305A (ja) 併用薬物送達のためのポリマー性ミセル
US11666539B2 (en) Synthetic lipid-like materials for brain delivery
WO2016050209A1 (zh) 一种异官能化聚乙二醇衍生物、制备方法及其生物相关物质
CN104530415A (zh) 一种异官能化y型聚乙二醇衍生物、制备方法及其生物相关物质
JP2022507781A5 (https=)
JP2020063250A (ja) ピロリドン誘導体、オリゴマー及びポリマー
JP2022513400A5 (https=)
JP2025148380A5 (https=)
JP2626654B2 (ja) 標的指向性高分子医薬化合物及びその中間体
JP2019178158A (ja) ポリマーリンカーおよびそれらの使用法
JP2004529118A5 (https=)
JP2018024590A (ja) 標的認識型組成物及びその用途
US12419964B2 (en) Antibody drug conjugate (ADC) targeting Nectin 4 and comprising an exatecan payload
WO2025064424A1 (en) Tandem-cleavage linkers for antibody-drug conjugates and uses thereof
JP2025506357A5 (https=)
HK40103161A (zh) 不饱和的树枝状聚合物组合物、有关的制剂、及其使用方法
EA053172B1 (ru) Активируемый ферментами аутореактивный линкер, обладающий усовершенствованными физико-химическими и фармакологическими свойствами