JP2024540402A5 - - Google Patents

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Publication number
JP2024540402A5
JP2024540402A5 JP2024527084A JP2024527084A JP2024540402A5 JP 2024540402 A5 JP2024540402 A5 JP 2024540402A5 JP 2024527084 A JP2024527084 A JP 2024527084A JP 2024527084 A JP2024527084 A JP 2024527084A JP 2024540402 A5 JP2024540402 A5 JP 2024540402A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound according
structural formula
immune complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024527084A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540402A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/048735 external-priority patent/WO2023081230A1/en
Publication of JP2024540402A publication Critical patent/JP2024540402A/ja
Publication of JP2024540402A5 publication Critical patent/JP2024540402A5/ja
Pending legal-status Critical Current

Links

JP2024527084A 2021-11-03 2022-11-02 新規オーリスタチン類似体およびその免疫複合体 Pending JP2024540402A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163275177P 2021-11-03 2021-11-03
US63/275,177 2021-11-03
US202163295476P 2021-12-30 2021-12-30
US63/295,476 2021-12-30
PCT/US2022/048735 WO2023081230A1 (en) 2021-11-03 2022-11-02 Novel auristatin analogs and immunoconjugates thereof

Publications (2)

Publication Number Publication Date
JP2024540402A JP2024540402A (ja) 2024-10-31
JP2024540402A5 true JP2024540402A5 (enExample) 2025-11-12

Family

ID=86241915

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024527084A Pending JP2024540402A (ja) 2021-11-03 2022-11-02 新規オーリスタチン類似体およびその免疫複合体

Country Status (10)

Country Link
US (1) US20260131016A1 (enExample)
EP (1) EP4426714A4 (enExample)
JP (1) JP2024540402A (enExample)
KR (1) KR20240110584A (enExample)
AU (1) AU2022380491A1 (enExample)
CA (1) CA3236944A1 (enExample)
IL (1) IL312533A (enExample)
MX (1) MX2024005342A (enExample)
TW (1) TW202334176A (enExample)
WO (1) WO2023081230A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4786483A1 (en) 2023-09-26 2026-08-05 Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. Auristatin derivative and antibody-drug conjugate thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2605443T3 (es) * 2003-11-06 2017-03-14 Seattle Genetics, Inc. Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia
US20130190248A1 (en) * 2011-07-26 2013-07-25 Agensys, Inc. Substituted peptide analogs
US20130280282A1 (en) * 2012-04-24 2013-10-24 Daiichi Sankyo Co., Ltd. Dr5 ligand drug conjugates
AR097161A1 (es) * 2013-08-01 2016-02-24 Agensys Inc Conjugados de fármacos anticuerpo (adc) que se unen a las proteínas cd37
PL3204425T3 (pl) * 2014-10-09 2021-03-08 Genzyme Corporation Glikomodyfikowane koniugaty przeciwciał z lekami
US20170014524A1 (en) * 2015-07-15 2017-01-19 The California Institute For Biomedical Research Auristatin-antibody conjugates and uses thereof

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