JP2024535145A - 改変ワクシニアウイルスアンカラ（ｍｖａ）による細胞傷害性導入遺伝子発現を下方調節するためのマイクロｒｎａの利用 - Google Patents

改変ワクシニアウイルスアンカラ（ｍｖａ）による細胞傷害性導入遺伝子発現を下方調節するためのマイクロｒｎａの利用 Download PDF

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JP2024535145A
JP2024535145A JP2024513977A JP2024513977A JP2024535145A JP 2024535145 A JP2024535145 A JP 2024535145A JP 2024513977 A JP2024513977 A JP 2024513977A JP 2024513977 A JP2024513977 A JP 2024513977A JP 2024535145 A JP2024535145 A JP 2024535145A
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mva
mirblock
seq
rsv
transgene
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ハウスマン・ユルゲン
カッラ・マルクス
シュヴェネカー・マルク
ハビャン・マティアス
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バヴァリアン・ノルディック・アクティーゼルスカブ
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JP2024513977A 2021-09-03 2022-09-02 改変ワクシニアウイルスアンカラ（ｍｖａ）による細胞傷害性導入遺伝子発現を下方調節するためのマイクロｒｎａの利用 Pending JP2024535145A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21194940 2021-09-03
EP21194940.9 2021-09-03
PCT/EP2022/074510 WO2023031428A1 (en) 2021-09-03 2022-09-02 Utilization of micro-rna for downregulation of cytotoxic transgene expression by modified vaccinia virus ankara (mva)

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JP2024535145A true JP2024535145A (ja) 2024-09-27
JP2024535145A5 JP2024535145A5 (https=) 2025-08-12

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JP2024513977A Pending JP2024535145A (ja) 2021-09-03 2022-09-02 改変ワクシニアウイルスアンカラ（ｍｖａ）による細胞傷害性導入遺伝子発現を下方調節するためのマイクロｒｎａの利用

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US (1) US20240392257A1 (https=)
EP (1) EP4396333A1 (https=)
JP (1) JP2024535145A (https=)
KR (1) KR20240051214A (https=)
CN (1) CN118234850A (https=)
AU (1) AU2022338199A1 (https=)
CA (1) CA3230406A1 (https=)
IL (1) IL311078A (https=)
MX (1) MX2024002641A (https=)
WO (1) WO2023031428A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024188801A1 (en) * 2023-03-10 2024-09-19 Bavarian Nordic A/S Use of quail cell lines for poxvirus production
WO2024245722A2 (en) * 2023-05-26 2024-12-05 Probiogen Ag Rapid selection system for the generation of recombinant enveloped viruses
WO2025120141A1 (en) * 2023-12-08 2025-06-12 Bavarian Nordic A/S Downregulation of yield-reducing transgenes expressed by poxvirus
WO2025153852A1 (en) * 2024-01-17 2025-07-24 1. Revvity Gene Delivery Gmbh Production of viral vectors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA76731C2 (uk) 2000-11-23 2006-09-15 Баваріан Нордік А/С Штам mva-bn модифікованого вірусу коров'ячої віспи ankara, фармацевтична композиція, вакцина, застосування mva-bn для приготування лікарського препарату та для приготування вакцини, спосіб введення гомологічної і/або гетерологічної послідовності нуклеїнової кислоти в клітини-мішені in vitro, спосіб одержання пептиду або білка, спосіб одержання mva-bn, клітина, набір для основної/бустерної імунізації
EP2345665A3 (en) 2001-12-04 2012-02-15 Bavarian Nordic A/S Flavivirus NS1 subunit vaccine
US20060185027A1 (en) * 2004-12-23 2006-08-17 David Bartel Systems and methods for identifying miRNA targets and for altering miRNA and target expression
GB2469043B (en) * 2009-03-30 2011-02-23 Lotus Car A reheated gas turbine system having a fuel cell
WO2013059498A1 (en) * 2011-10-18 2013-04-25 Geovax, Inc. Mva vectors expressing polypeptides and having high level production in certain cell lines
KR102435054B1 (ko) * 2012-08-01 2022-08-22 버베리안 노딕 에이/에스 재조합 변형된 백시니아 바이러스 앙카라(ankara) (mva) 호흡기 신시티알 바이러스(rsv) 백신
EP2912183B1 (en) 2012-10-28 2020-05-06 Bavarian Nordic A/S Pr13.5 promoter for robust t-cell and antibody responses

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US20240392257A1 (en) 2024-11-28
AU2022338199A1 (en) 2024-03-14
MX2024002641A (es) 2024-05-10
IL311078A (en) 2024-04-01
CA3230406A1 (en) 2023-03-09
EP4396333A1 (en) 2024-07-10
KR20240051214A (ko) 2024-04-19
CN118234850A (zh) 2024-06-21
WO2023031428A1 (en) 2023-03-09

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