JP2024533182A5 - - Google Patents

Info

Publication number
JP2024533182A5
JP2024533182A5 JP2024514040A JP2024514040A JP2024533182A5 JP 2024533182 A5 JP2024533182 A5 JP 2024533182A5 JP 2024514040 A JP2024514040 A JP 2024514040A JP 2024514040 A JP2024514040 A JP 2024514040A JP 2024533182 A5 JP2024533182 A5 JP 2024533182A5
Authority
JP
Japan
Prior art keywords
composition according
pharmaceutically acceptable
disease
disorder
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024514040A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024533182A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/042496 external-priority patent/WO2023034589A1/en
Publication of JP2024533182A publication Critical patent/JP2024533182A/ja
Publication of JP2024533182A5 publication Critical patent/JP2024533182A5/ja
Pending legal-status Critical Current

Links

JP2024514040A 2021-09-02 2022-09-02 酸性pHで増強された効力を有するN-メチル-D-アスパラギン酸受容体のGluN2Bサブユニット選択的アンタゴニスト Pending JP2024533182A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163240125P 2021-09-02 2021-09-02
US63/240,125 2021-09-02
PCT/US2022/042496 WO2023034589A1 (en) 2021-09-02 2022-09-02 Glun2b-subunit selective antagonists of the n-methyl-d-aspartate receptors with enhanced potency at acidic ph

Publications (2)

Publication Number Publication Date
JP2024533182A JP2024533182A (ja) 2024-09-12
JP2024533182A5 true JP2024533182A5 (enExample) 2025-09-11

Family

ID=85412916

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024514040A Pending JP2024533182A (ja) 2021-09-02 2022-09-02 酸性pHで増強された効力を有するN-メチル-D-アスパラギン酸受容体のGluN2Bサブユニット選択的アンタゴニスト

Country Status (7)

Country Link
US (2) US20240360091A1 (enExample)
EP (1) EP4395783A4 (enExample)
JP (1) JP2024533182A (enExample)
CN (1) CN118019541A (enExample)
AU (1) AU2022339672B2 (enExample)
CA (1) CA3230601A1 (enExample)
WO (1) WO2023034589A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025255430A1 (en) * 2024-06-07 2025-12-11 Seyltx, Inc. Compositions and methods for treating chronic cough

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002028814A2 (en) * 2000-10-06 2002-04-11 Regents Of The University Of California Nmda receptor channel blocker with neuroprotective activity
WO2002072542A2 (en) 2001-03-08 2002-09-19 Emory University Ph-dependent nmda receptor antagonists
US20060199864A1 (en) * 2004-08-23 2006-09-07 Traynelis Stephen F Selection of pH-dependent compounds for in vivo therapy
WO2006060461A1 (en) * 2004-12-03 2006-06-08 Schering Corporation Substituted piperazines as cb1 antagonists
CN103058957A (zh) * 2007-06-29 2013-04-24 埃莫里大学 用于神经保护的nmda受体拮抗剂
CA2704475A1 (en) 2007-11-06 2009-05-14 Emory University Methods of identifying improved nmda receptor antagonists
BRPI0912362A2 (pt) * 2008-05-09 2015-10-06 Univ Emory antagonista do receptor nmda para o tratamento de transtornos neuropsiquiátricos
AU2010331949A1 (en) 2009-12-15 2012-07-12 Neurop, Inc. Compounds for the treatment of neurologic disorders
WO2013170072A2 (en) 2012-05-09 2013-11-14 Neurop, Inc. Compounds for the treatment of neurological disorders

Similar Documents

Publication Publication Date Title
AU2024203353B2 (en) Compositions and method of treating cancer
EP3908570B1 (en) Ketamine pamoate and use thereof
RU2017119222A (ru) Нейро-аттенуирующие кетаминовые и норкетаминовые соединения, их производные и способы их получения
JP2017511339A5 (enExample)
US6833478B2 (en) N,N-dinitramide salts as solubilizing agents for biologically active agents
JPS62185017A (ja) 変形性関節症および関連した病気の治療のためのn−アセチルグルコサミンの使用
JP2022549335A5 (enExample)
US2937117A (en) Process for lowering high blood cholesterol levels
CN120957718A (zh) 任选地与n-酰基乙醇胺组合地包含n,n-二甲基色胺的组合物及其用途
JPS5910585A (ja) スピロスクシンイミド誘導体のアルツハイマ−型痴「ほう」の治療における使用
CN121079078A (zh) 任选地与n-酰基乙醇胺组合地包含麦角酸二乙酰胺的组合物及其用途
CN120916771A (zh) 任选地与n-酰基乙醇胺组合地包含裸盖菇素的组合物及其用途
JPH02502185A (ja) 咳および気管支収縮の治療用5‐ht3レセプター拮抗物質
JP2025517509A5 (enExample)
US7919486B2 (en) Use of gallium(III) complexes for the treatment of melanomas
JP2022515373A5 (enExample)
CN121793970A (zh) Nek7激酶抑制剂的药物组合物
CN106794363A (zh) 在单一丸剂/片剂/胶囊中米诺环素、氟康唑和阿托伐他汀在治疗多发性硬化中的用途
JPH05163145A (ja) 脳血管性痴呆改善剤
CN120936351A (zh) 任选地与n-酰基乙醇胺组合地包含3,4-亚甲基二氧基甲基苯丙胺的组合物及其用途
EP2912046A1 (en) Phosphate esters of bimatoprost and the prostamides
WO2002076993A1 (de) Tumorhemmende siliciumverbindungen
CA3118954C (en) Ketamine pamoate and use thereof
EP1414829A2 (de) Tumorhemmende cerverbindungen
WO2010128309A1 (en) Combination therapy comprising a taxane and a sigma receptor ligand sauch as rimcazole