JP2024527997A5 - - Google Patents

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Publication number
JP2024527997A5
JP2024527997A5 JP2024505066A JP2024505066A JP2024527997A5 JP 2024527997 A5 JP2024527997 A5 JP 2024527997A5 JP 2024505066 A JP2024505066 A JP 2024505066A JP 2024505066 A JP2024505066 A JP 2024505066A JP 2024527997 A5 JP2024527997 A5 JP 2024527997A5
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JP
Japan
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JP2024505066A
Other languages
Japanese (ja)
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JPWO2023010073A5 (https=
JP2024527997A (ja
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Publication date
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Priority claimed from PCT/US2022/074251 external-priority patent/WO2023010073A1/en
Publication of JP2024527997A publication Critical patent/JP2024527997A/ja
Publication of JPWO2023010073A5 publication Critical patent/JPWO2023010073A5/ja
Publication of JP2024527997A5 publication Critical patent/JP2024527997A5/ja
Pending legal-status Critical Current

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JP2024505066A 2021-07-28 2022-07-28 T細胞持続性及び機能を改善するための組成物及び方法 Pending JP2024527997A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163226559P 2021-07-28 2021-07-28
US63/226,559 2021-07-28
PCT/US2022/074251 WO2023010073A1 (en) 2021-07-28 2022-07-28 Compositions and methods for improving t cell persistence and function

Publications (3)

Publication Number Publication Date
JP2024527997A JP2024527997A (ja) 2024-07-26
JPWO2023010073A5 JPWO2023010073A5 (https=) 2025-08-04
JP2024527997A5 true JP2024527997A5 (https=) 2025-08-04

Family

ID=85087331

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024505066A Pending JP2024527997A (ja) 2021-07-28 2022-07-28 T細胞持続性及び機能を改善するための組成物及び方法

Country Status (5)

Country Link
US (1) US20240327826A1 (https=)
EP (1) EP4376858A4 (https=)
JP (1) JP2024527997A (https=)
CN (1) CN117813102A (https=)
WO (1) WO2023010073A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024173916A1 (en) * 2023-02-17 2024-08-22 Dana-Farber Cancer Institute, Inc. Compositions and methods of preventing t cell exhaustion
WO2025185585A1 (zh) * 2024-03-05 2025-09-12 上海沙砾生物科技有限公司 一种鉴定靶标的方法及其应用
CN118345080B (zh) * 2024-06-17 2024-09-24 江苏柯菲平医药股份有限公司 一种抗耗竭t细胞及其制备方法、应用
CN119120385B (zh) * 2024-11-14 2025-03-14 四川大学华西医院 一种具有长效抑瘤效果的嵌合抗原受体t细胞及其制备方法和用途
CN121294362A (zh) * 2025-12-11 2026-01-09 良渚实验室 Tada2b基因在促进红系终末分化中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019084495A1 (en) * 2017-10-27 2019-05-02 The Trustees Of The University Of Pennsylvania IDENTIFICATION OF EPIGENETIC AND TRANSCRIPTIONAL TARGETS TO PREVENT AND REVERSE T-LYMPHOCYTE EXHAUST
US11400117B2 (en) * 2017-12-15 2022-08-02 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for inhibiting T cell exhaustion
US11447769B2 (en) * 2018-03-27 2022-09-20 The Trustees Of The University Of Pennsylvania Modified immune cells having enhanced function and methods for screening for same
CN110904045A (zh) * 2018-09-17 2020-03-24 中国科学院动物研究所 经修饰的t细胞、其制备方法及用途
US20220354889A1 (en) * 2019-03-26 2022-11-10 The Trustees Of The University Of Pennsylvania Dnmt3a knockout car t cells for adoptive immunotherapy
WO2020219682A2 (en) * 2019-04-24 2020-10-29 St. Jude Children's Research Hospital, Inc. Gene knock-outs to improve t cell function

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