JP2024527304A5 - - Google Patents

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Publication number
JP2024527304A5
JP2024527304A5 JP2023579695A JP2023579695A JP2024527304A5 JP 2024527304 A5 JP2024527304 A5 JP 2024527304A5 JP 2023579695 A JP2023579695 A JP 2023579695A JP 2023579695 A JP2023579695 A JP 2023579695A JP 2024527304 A5 JP2024527304 A5 JP 2024527304A5
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JP
Japan
Prior art keywords
pharmaceutical composition
phosphate
composition according
nucleotide sequence
modified nucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2023579695A
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English (en)
Japanese (ja)
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JP2024527304A (ja
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Priority claimed from PCT/US2022/035523 external-priority patent/WO2023278576A1/en
Publication of JP2024527304A publication Critical patent/JP2024527304A/ja
Publication of JP2024527304A5 publication Critical patent/JP2024527304A5/ja
Pending legal-status Critical Current

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JP2023579695A 2021-06-30 2022-06-29 アンジオテンシノーゲン（ａｇｔ）関連障害を治療するための方法および組成物 Pending JP2024527304A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163216758P 2021-06-30 2021-06-30
US63/216,758 2021-06-30
US202163276808P 2021-11-08 2021-11-08
US63/276,808 2021-11-08
PCT/US2022/035523 WO2023278576A1 (en) 2021-06-30 2022-06-29 Methods and compositions for treating an angiotensinogen- (agt-) associated disorder

Publications (2)

Publication Number Publication Date
JP2024527304A JP2024527304A (ja) 2024-07-24
JP2024527304A5 true JP2024527304A5 (https=) 2025-07-09

Family

ID=82701605

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023579695A Pending JP2024527304A (ja) 2021-06-30 2022-06-29 アンジオテンシノーゲン（ａｇｔ）関連障害を治療するための方法および組成物

Country Status (9)

Country Link
US (1) US20240247266A1 (https=)
EP (1) EP4363580A1 (https=)
JP (1) JP2024527304A (https=)
KR (1) KR20240026203A (https=)
AU (1) AU2022303164A1 (https=)
CA (1) CA3225469A1 (https=)
IL (1) IL309296A (https=)
MX (1) MX2023015489A (https=)
WO (1) WO2023278576A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI851574B (zh) 2018-05-14 2024-08-11 美商阿尼拉製藥公司 血管收縮素原（ＡＧＴ）ｉＲＮＡ組成物及其使用方法
IL312811A (en) 2021-11-16 2024-07-01 Shanghai Argo Biopharmaceutical Co Ltd Composition and method for inhibiting angiotensinogen (agt) protein expression
WO2024234831A1 (zh) * 2023-05-15 2024-11-21 苏州时安生物技术有限公司 一种用于调节血管紧张素原基因表达的双链rna、其缀合物、药物组合物及用途
CN119585433A (zh) * 2023-07-06 2025-03-07 石药集团中奇制药技术（石家庄）有限公司 一种抑制AGT基因表达的RNAi剂及其应用
TW202509216A (zh) * 2023-07-14 2025-03-01 大陸商北京安龍生物醫藥有限公司 靶向血管收縮素原的寡核苷酸及其用途
WO2025097040A1 (en) * 2023-11-03 2025-05-08 Ionis Pharmaceuticals, Inc. Methods and compositions for reducing angiotensinogen
TW202543655A (zh) * 2023-12-12 2025-11-16 美商艾拉倫製藥股份有限公司 用於治療血管收縮素原（ａｇｔ）相關疾患的方法及組成物
WO2026050125A1 (en) * 2024-08-28 2026-03-05 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating an angiotensinogen- (agt-) associated disorder

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