JP2024526356A5 - - Google Patents

Info

Publication number
JP2024526356A5
JP2024526356A5 JP2024502451A JP2024502451A JP2024526356A5 JP 2024526356 A5 JP2024526356 A5 JP 2024526356A5 JP 2024502451 A JP2024502451 A JP 2024502451A JP 2024502451 A JP2024502451 A JP 2024502451A JP 2024526356 A5 JP2024526356 A5 JP 2024526356A5
Authority
JP
Japan
Prior art keywords
rspo1
domain
recombinant variant
fusion protein
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024502451A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024526356A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/069925 external-priority patent/WO2023285686A2/en
Publication of JP2024526356A publication Critical patent/JP2024526356A/ja
Publication of JP2024526356A5 publication Critical patent/JP2024526356A5/ja
Pending legal-status Critical Current

Links

JP2024502451A 2021-07-15 2022-07-15 R-スポンジンタンパク質の組換えバリアントおよびその使用 Pending JP2024526356A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP21305993 2021-07-15
EP21305993.4 2021-07-15
EP22305328.1 2022-03-18
EP22305328 2022-03-18
PCT/EP2022/069925 WO2023285686A2 (en) 2021-07-15 2022-07-15 Recombinant variants of r-spondin proteins and their use

Publications (2)

Publication Number Publication Date
JP2024526356A JP2024526356A (ja) 2024-07-17
JP2024526356A5 true JP2024526356A5 (https=) 2025-07-22

Family

ID=82799950

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024502451A Pending JP2024526356A (ja) 2021-07-15 2022-07-15 R-スポンジンタンパク質の組換えバリアントおよびその使用

Country Status (9)

Country Link
US (2) US20240383952A1 (https=)
EP (1) EP4370535A2 (https=)
JP (1) JP2024526356A (https=)
KR (1) KR20240040088A (https=)
AU (1) AU2022311529A1 (https=)
CA (1) CA3225626A1 (https=)
IL (1) IL310154A (https=)
MX (1) MX2024000757A (https=)
WO (1) WO2023285686A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230241161A1 (en) * 2020-01-10 2023-08-03 Inserm (Institutnationaldelasanteetdelarecherchemedicale) Rspo1 proteins and their use
CN120813594A (zh) * 2023-01-19 2025-10-17 迪奥根克斯公司 R-spondin蛋白的重组变体及其用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4634665A (en) 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
GB8725529D0 (en) 1987-10-30 1987-12-02 Delta Biotechnology Ltd Polypeptides
US8377653B2 (en) 2005-02-11 2013-02-19 Icosagen Cell Factory Oü Viral expression plasmids for production of proteins, antibodies, enzymes, virus-like particles and for use in cell-based assays
US7790446B2 (en) 2005-02-11 2010-09-07 Kosagen Cell Factory Oü Vectors, cell lines and their use in obtaining extended episomal maintenance replication of hybrid plasmids and expression of gene products
AU2013204484B2 (en) * 2011-07-15 2016-05-12 Oncomed Pharmaceuticals, Inc. RSPO binding agents and uses thereof
WO2013049375A2 (en) * 2011-09-28 2013-04-04 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for modulating beta cell proliferation
US9783784B2 (en) * 2013-01-04 2017-10-10 City Of Hope Methods for establishing and improving the survival of a population of pancreatic progenitor or stem cells
US9777052B2 (en) * 2014-12-02 2017-10-03 The Board Of Regents Of The University Of Oklahoma R-spondin variants, compositions, and methods of use
WO2018140821A1 (en) * 2017-01-26 2018-08-02 Surrozen, Inc. Tissue-specific wnt signal enhancing molecules and uses thereof
JP2021020900A (ja) * 2019-07-29 2021-02-18 国立大学法人北海道大学 糖代謝異常改善剤

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