JP2024525723A5 - - Google Patents

Info

Publication number
JP2024525723A5
JP2024525723A5 JP2024501737A JP2024501737A JP2024525723A5 JP 2024525723 A5 JP2024525723 A5 JP 2024525723A5 JP 2024501737 A JP2024501737 A JP 2024501737A JP 2024501737 A JP2024501737 A JP 2024501737A JP 2024525723 A5 JP2024525723 A5 JP 2024525723A5
Authority
JP
Japan
Prior art keywords
alkyl
phe
peptide inhibitor
cyano
bicyclic peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024501737A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525723A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/037202 external-priority patent/WO2023288017A2/en
Publication of JP2024525723A publication Critical patent/JP2024525723A/ja
Publication of JP2024525723A5 publication Critical patent/JP2024525723A5/ja
Pending legal-status Critical Current

Links

JP2024501737A 2021-07-14 2022-07-14 インターロイキン-23受容体の二環式ペプチド阻害剤 Pending JP2024525723A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163221854P 2021-07-14 2021-07-14
US63/221,854 2021-07-14
PCT/US2022/037202 WO2023288017A2 (en) 2021-07-14 2022-07-14 Bicyclic peptide inhibitors of interleukin-23 receptor

Publications (2)

Publication Number Publication Date
JP2024525723A JP2024525723A (ja) 2024-07-12
JP2024525723A5 true JP2024525723A5 (https=) 2025-07-24

Family

ID=84920518

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024501737A Pending JP2024525723A (ja) 2021-07-14 2022-07-14 インターロイキン-23受容体の二環式ペプチド阻害剤

Country Status (12)

Country Link
US (1) US20240352073A1 (https=)
EP (1) EP4370532A4 (https=)
JP (1) JP2024525723A (https=)
KR (1) KR20240034223A (https=)
CN (1) CN117980320A (https=)
AR (1) AR126457A1 (https=)
AU (1) AU2022310347A1 (https=)
CA (1) CA3226492A1 (https=)
MX (1) MX2024000761A (https=)
TW (1) TW202321275A (https=)
UY (1) UY39858A (https=)
WO (1) WO2023288017A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4091624A1 (en) 2013-03-15 2022-11-23 Protagonist Therapeutics, Inc. Hepcidin analogues and uses thereof
HRP20211448T1 (hr) 2014-05-16 2021-12-24 Protagonist Therapeutics, Inc. Alfa4beta7 integrin tioeter peptidni antagonisti
CN107206254B (zh) 2014-07-17 2021-08-24 领导医疗有限公司 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途
CA3089868A1 (en) 2018-02-08 2019-08-15 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
AU2021209086A1 (en) 2020-01-15 2022-08-04 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
JP7397239B2 (ja) 2020-11-20 2023-12-12 ヤンセン ファーマシューティカ エヌ.ベー. インターロイキン-23受容体のペプチド阻害剤の組成物
EP4370146A4 (en) 2021-07-14 2025-05-21 Janssen Biotech, Inc. Lipidated peptide inhibitors of the interleukin-23 receptor
WO2024155551A1 (en) * 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Polycyclic peptide inhibitors of interleukin-23 receptor
EP4471049A1 (en) 2023-06-01 2024-12-04 Zealand Pharma A/S Peptide inhibitors of interleukin-23 receptor
EP4471048A1 (en) 2023-06-01 2024-12-04 Zealand Pharma A/S Peptide inhibitors of interleukin-23 receptor
CN121909205A (zh) 2023-09-08 2026-04-21 赛诺菲 作为选择性il-23受体抑制剂的新型肽
CN121794283A (zh) 2023-09-08 2026-04-03 赛诺菲 作为选择性il-23受体抑制剂的新型肽
WO2025076414A1 (en) * 2023-10-06 2025-04-10 The Children's Medical Center Corporation Compositions and methods for selecting a subject for inflammatory bowel disease treatment
WO2026013260A1 (en) 2024-07-12 2026-01-15 Zealand Pharma A/S Peptide inhibitors of interleukin-23 receptor
WO2026041110A1 (zh) * 2024-08-22 2026-02-26 上海瀚辰星泰医药科技有限公司 一种多肽化合物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107206254B (zh) * 2014-07-17 2021-08-24 领导医疗有限公司 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途
US10301371B2 (en) * 2014-10-01 2019-05-28 Protagonist Therapeutics, Inc. Cyclic monomer and dimer peptides having integrin antagonist activity
MX384213B (es) * 2015-07-15 2025-03-14 Protagonist Therapeutics Inc Inhibidores peptidicos del receptor de interleucina 23 y su uso para tratar enfermedades inflamatorias.
JP7100034B2 (ja) * 2016-12-06 2022-07-12 シュティヒティング・ヴォール・デ・テクニシェ・ヴェテンシャッペン 多環式ペプチド及びそれらの調製方法
WO2019034866A1 (en) * 2017-08-14 2019-02-21 Bicyclerd Limited BICYCLIC PEPTIDE LIGANDS CONJUGATES AND USES THEREOF
CN111712509A (zh) * 2017-12-15 2020-09-25 詹森生物科技公司 作为sting激动剂的环状二核苷酸
WO2020014646A1 (en) * 2018-07-12 2020-01-16 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
WO2021007433A1 (en) * 2019-07-10 2021-01-14 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

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