JP2024520555A5 - - Google Patents
Info
- Publication number
- JP2024520555A5 JP2024520555A5 JP2023573588A JP2023573588A JP2024520555A5 JP 2024520555 A5 JP2024520555 A5 JP 2024520555A5 JP 2023573588 A JP2023573588 A JP 2023573588A JP 2023573588 A JP2023573588 A JP 2023573588A JP 2024520555 A5 JP2024520555 A5 JP 2024520555A5
- Authority
- JP
- Japan
- Prior art keywords
- asddna
- chain
- group
- disorders
- molecule according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163195008P | 2021-05-29 | 2021-05-29 | |
| US63/195,008 | 2021-05-29 | ||
| PCT/US2022/031658 WO2022256351A1 (en) | 2021-05-29 | 2022-05-31 | Asymmetric short duplex dna as a novel gene silencing technology and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024520555A JP2024520555A (ja) | 2024-05-24 |
| JP2024520555A5 true JP2024520555A5 (https=) | 2025-06-09 |
Family
ID=82361361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023573588A Pending JP2024520555A (ja) | 2021-05-29 | 2022-05-31 | 新規遺伝子サイレンシング技術としての非対称短鎖二重鎖ｄｎａおよびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240271137A1 (https=) |
| EP (1) | EP4347829A1 (https=) |
| JP (1) | JP2024520555A (https=) |
| KR (1) | KR20240014532A (https=) |
| CN (1) | CN117858946A (https=) |
| AU (1) | AU2022285661A1 (https=) |
| CA (1) | CA3221935A1 (https=) |
| TW (1) | TW202309286A (https=) |
| WO (1) | WO2022256351A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR133304A1 (es) * | 2023-07-21 | 2025-09-17 | Visirna Therapeutics Suzhou Co Ltd | Agentes oligonucleotídicos de cadena doble y sus usos |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2429814C (en) | 2000-12-01 | 2014-02-18 | Thomas Tuschl | Rna interference mediating small rna molecules |
| US6962944B2 (en) | 2001-07-31 | 2005-11-08 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
| US7074824B2 (en) | 2001-07-31 | 2006-07-11 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
| WO2004041889A2 (en) | 2002-11-05 | 2004-05-21 | Isis Pharmaceuticals, Inc. | Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation |
| EP1661905B9 (en) | 2003-08-28 | 2012-12-19 | IMANISHI, Takeshi | Novel artificial nucleic acids of n-o bond crosslinkage type |
| CA2538252C (en) | 2003-09-18 | 2014-02-25 | Isis Pharmaceuticals, Inc. | 4'-thionucleosides and oligomeric compounds |
| US7919472B2 (en) | 2004-09-17 | 2011-04-05 | Isis Pharmaceuticals, Inc. | Enhanced antisense oligonucleotides |
| WO2007090071A2 (en) | 2006-01-27 | 2007-08-09 | Isis Pharmaceuticals, Inc. | 6-modified bicyclic nucleic acid analogs |
| JP2009536222A (ja) | 2006-05-05 | 2009-10-08 | アイシス ファーマシューティカルズ， インコーポレーテッド | Ｐｃｓｋ９の発現を調節するための化合物および方法 |
| AU2007249349B2 (en) | 2006-05-11 | 2012-03-08 | Isis Pharmaceuticals, Inc. | 5'-Modified bicyclic nucleic acid analogs |
| WO2008101157A1 (en) | 2007-02-15 | 2008-08-21 | Isis Pharmaceuticals, Inc. | 5'-substituted-2'-f modified nucleosides and oligomeric compounds prepared therefrom |
| CA2688321A1 (en) | 2007-05-30 | 2008-12-11 | Isis Pharmaceuticals, Inc. | N-substituted-aminomethylene bridged bicyclic nucleic acid analogs |
| DK2173760T4 (en) | 2007-06-08 | 2016-02-08 | Isis Pharmaceuticals Inc | Carbocyclic bicyclic nukleinsyreanaloge |
| AU2008272918B2 (en) | 2007-07-05 | 2012-09-13 | Isis Pharmaceuticals, Inc. | 6-disubstituted bicyclic nucleic acid analogs |
| EP3889261A1 (en) | 2007-08-27 | 2021-10-06 | 1Globe Health Institute LLC | Compositions of asymmetric interfering rna and uses thereof |
| KR101728655B1 (ko) * | 2008-12-18 | 2017-04-19 | 다이서나 파마수이티컬, 인크. | 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법 |
| EP3004347B1 (en) * | 2013-05-30 | 2018-09-26 | National University Corporation Tokyo Medical and Dental University | Double-stranded agents for delivering therapeutic oligonucleotides |
| JPWO2017068790A1 (ja) * | 2015-10-23 | 2018-08-09 | レナセラピューティクス株式会社 | 核酸複合体 |
| US11260134B2 (en) * | 2016-09-29 | 2022-03-01 | National University Corporation Tokyo Medical And Dental University | Double-stranded nucleic acid complex having overhang |
-
2022
- 2022-05-31 KR KR1020237045354A patent/KR20240014532A/ko active Pending
- 2022-05-31 EP EP22736414.8A patent/EP4347829A1/en active Pending
- 2022-05-31 JP JP2023573588A patent/JP2024520555A/ja active Pending
- 2022-05-31 US US18/564,562 patent/US20240271137A1/en active Pending
- 2022-05-31 CA CA3221935A patent/CA3221935A1/en active Pending
- 2022-05-31 AU AU2022285661A patent/AU2022285661A1/en active Pending
- 2022-05-31 CN CN202280038730.3A patent/CN117858946A/zh active Pending
- 2022-05-31 WO PCT/US2022/031658 patent/WO2022256351A1/en not_active Ceased
- 2022-06-14 TW TW111122094A patent/TW202309286A/zh unknown
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