JP2024520556A5 - - Google Patents
Info
- Publication number
- JP2024520556A5 JP2024520556A5 JP2023573589A JP2023573589A JP2024520556A5 JP 2024520556 A5 JP2024520556 A5 JP 2024520556A5 JP 2023573589 A JP2023573589 A JP 2023573589A JP 2023573589 A JP2023573589 A JP 2023573589A JP 2024520556 A5 JP2024520556 A5 JP 2024520556A5
- Authority
- JP
- Japan
- Prior art keywords
- sddna
- group
- modified
- molecule according
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163195010P | 2021-05-29 | 2021-05-29 | |
| US63/195,010 | 2021-05-29 | ||
| PCT/US2022/031666 WO2022256354A1 (en) | 2021-05-29 | 2022-05-31 | Short duplex dna as a novel gene silencing technology and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024520556A JP2024520556A (ja) | 2024-05-24 |
| JP2024520556A5 true JP2024520556A5 (https=) | 2025-06-10 |
Family
ID=82358463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023573589A Pending JP2024520556A (ja) | 2021-05-29 | 2022-05-31 | 新規遺伝子サイレンシング技術としての短鎖二重鎖ｄｎａおよびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240254490A1 (https=) |
| EP (1) | EP4347828A1 (https=) |
| JP (1) | JP2024520556A (https=) |
| KR (1) | KR20240014533A (https=) |
| CN (1) | CN118369428A (https=) |
| AU (1) | AU2022286925A1 (https=) |
| CA (1) | CA3221923A1 (https=) |
| TW (1) | TW202313977A (https=) |
| WO (1) | WO2022256354A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR133304A1 (es) * | 2023-07-21 | 2025-09-17 | Visirna Therapeutics Suzhou Co Ltd | Agentes oligonucleotídicos de cadena doble y sus usos |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2429814C (en) | 2000-12-01 | 2014-02-18 | Thomas Tuschl | Rna interference mediating small rna molecules |
| US7074824B2 (en) | 2001-07-31 | 2006-07-11 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
| US6962944B2 (en) | 2001-07-31 | 2005-11-08 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
| WO2004041889A2 (en) | 2002-11-05 | 2004-05-21 | Isis Pharmaceuticals, Inc. | Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation |
| EP1661905B9 (en) | 2003-08-28 | 2012-12-19 | IMANISHI, Takeshi | Novel artificial nucleic acids of n-o bond crosslinkage type |
| CA2538252C (en) | 2003-09-18 | 2014-02-25 | Isis Pharmaceuticals, Inc. | 4'-thionucleosides and oligomeric compounds |
| US7919472B2 (en) | 2004-09-17 | 2011-04-05 | Isis Pharmaceuticals, Inc. | Enhanced antisense oligonucleotides |
| WO2007090071A2 (en) | 2006-01-27 | 2007-08-09 | Isis Pharmaceuticals, Inc. | 6-modified bicyclic nucleic acid analogs |
| JP2009536222A (ja) | 2006-05-05 | 2009-10-08 | アイシス ファーマシューティカルズ， インコーポレーテッド | Ｐｃｓｋ９の発現を調節するための化合物および方法 |
| AU2007249349B2 (en) | 2006-05-11 | 2012-03-08 | Isis Pharmaceuticals, Inc. | 5'-Modified bicyclic nucleic acid analogs |
| WO2008101157A1 (en) | 2007-02-15 | 2008-08-21 | Isis Pharmaceuticals, Inc. | 5'-substituted-2'-f modified nucleosides and oligomeric compounds prepared therefrom |
| CA2688321A1 (en) | 2007-05-30 | 2008-12-11 | Isis Pharmaceuticals, Inc. | N-substituted-aminomethylene bridged bicyclic nucleic acid analogs |
| DK2173760T4 (en) | 2007-06-08 | 2016-02-08 | Isis Pharmaceuticals Inc | Carbocyclic bicyclic nukleinsyreanaloge |
| AU2008272918B2 (en) | 2007-07-05 | 2012-09-13 | Isis Pharmaceuticals, Inc. | 6-disubstituted bicyclic nucleic acid analogs |
| EP3889261A1 (en) | 2007-08-27 | 2021-10-06 | 1Globe Health Institute LLC | Compositions of asymmetric interfering rna and uses thereof |
| EP3004347B1 (en) * | 2013-05-30 | 2018-09-26 | National University Corporation Tokyo Medical and Dental University | Double-stranded agents for delivering therapeutic oligonucleotides |
| JPWO2017068790A1 (ja) * | 2015-10-23 | 2018-08-09 | レナセラピューティクス株式会社 | 核酸複合体 |
| US11260134B2 (en) * | 2016-09-29 | 2022-03-01 | National University Corporation Tokyo Medical And Dental University | Double-stranded nucleic acid complex having overhang |
-
2022
- 2022-05-31 EP EP22736074.0A patent/EP4347828A1/en active Pending
- 2022-05-31 CA CA3221923A patent/CA3221923A1/en active Pending
- 2022-05-31 WO PCT/US2022/031666 patent/WO2022256354A1/en not_active Ceased
- 2022-05-31 US US18/564,602 patent/US20240254490A1/en active Pending
- 2022-05-31 KR KR1020237045355A patent/KR20240014533A/ko active Pending
- 2022-05-31 CN CN202280038744.5A patent/CN118369428A/zh active Pending
- 2022-05-31 AU AU2022286925A patent/AU2022286925A1/en active Pending
- 2022-05-31 JP JP2023573589A patent/JP2024520556A/ja active Pending
- 2022-06-14 TW TW111122093A patent/TW202313977A/zh unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3647318B1 (en) | Linkage modified oligomeric compounds | |
| CN105121452A (zh) | 三环核苷和由其制备的寡聚化合物 | |
| TW201819397A (zh) | 減少atxn3表現之化合物及方法 | |
| KR20200024793A (ko) | 알파-ENaC의 발현을 억제하기 위한 RNAi 작용제 및 사용 방법 | |
| EP4463553B1 (en) | Advanced rna targeting (arnatar) | |
| CN111902537A (zh) | Dnm2表达的调节剂 | |
| CN104321334A (zh) | 三环核苷及由其制备的低聚化合物 | |
| JP2024520556A5 (https=) | ||
| JP2024520555A5 (https=) | ||
| JP7128517B2 (ja) | 副作用を減じたアンチセンス核酸 | |
| Pontarelli et al. | Arabinonucleic acids containing C5-propynyl modifications form stable hybrid duplexes with RNA that are efficiently degraded by E. coli RNase H | |
| US20240336920A1 (en) | Threose nucleic acid antisense oligonucleotides and methods thereof | |
| TW202309286A (zh) | 作為新穎基因靜默技術的非對稱短雙股ｄｎａ及其應用 | |
| TW202313977A (zh) | 作為新穎基因靜默技術的短雙股ｄｎａ及其應用 | |
| JP2025542580A (ja) | 遺伝子サイレンシング技術としての、デオキシリボヌクレオチドが散在している短鎖二重鎖ｒｎａ、およびその使用 | |
| WO2024040041A1 (en) | Regulation of activity of rnai molecules | |
| JP7216381B2 (ja) | Ｒｎａ作用抑制剤及びその利用 | |
| HK40108297A (zh) | 作为新型基因沉默技术的短双链体dna及其应用 | |
| HK40129500A (en) | Translation enhancing nucleic acid compounds: aso coupled translation - upregulation 1 (act-up1) and uses thereof | |
| JP2025542579A (ja) | 遺伝子サイレンシング技術としての、デオキシリボヌクレオチドが散在している非対称短鎖二重鎖ｒｎａ、およびその使用 | |
| HK40110327A (zh) | 作为新型基因沉默技术的非对称短双链体dna及其应用 | |
| CN120676949A (zh) | 反义RNA（asRNA）技术及其应用 | |
| EP4671372A2 (en) | Translation-enhancing nucleic acid compounds: Upward regulation 1 coupled with ASO (ACT-UP1) and their uses | |
| HK40128552A (en) | Advanced rna targeting (arnatar) | |
| HK40111629A (zh) | 苏糖核酸反义寡核苷酸及其方法 |