JP2024520522A5 - - Google Patents
Info
- Publication number
- JP2024520522A5 JP2024520522A5 JP2023573300A JP2023573300A JP2024520522A5 JP 2024520522 A5 JP2024520522 A5 JP 2024520522A5 JP 2023573300 A JP2023573300 A JP 2023573300A JP 2023573300 A JP2023573300 A JP 2023573300A JP 2024520522 A5 JP2024520522 A5 JP 2024520522A5
- Authority
- JP
- Japan
- Prior art keywords
- rnai agent
- agent according
- nucleotide
- sense strand
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163194370P | 2021-05-28 | 2021-05-28 | |
| US63/194,370 | 2021-05-28 | ||
| PCT/US2022/030969 WO2022251394A1 (en) | 2021-05-28 | 2022-05-25 | Rnai agents for inhibiting expression of mucin 5ac (muc5ac), compositions thereof, and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024520522A JP2024520522A (ja) | 2024-05-24 |
| JP2024520522A5 true JP2024520522A5 (enExample) | 2025-06-02 |
Family
ID=84229166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023573300A Pending JP2024520522A (ja) | 2021-05-28 | 2022-05-25 | ムチン５ＡＣ（ＭＵＣ５ＡＣ）の発現を阻害するためのＲＮＡｉ剤、その組成物、及び使用方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12365897B2 (enExample) |
| EP (1) | EP4352229A4 (enExample) |
| JP (1) | JP2024520522A (enExample) |
| KR (1) | KR20240014067A (enExample) |
| CN (1) | CN117858949A (enExample) |
| AU (1) | AU2022280863A1 (enExample) |
| BR (1) | BR112023024615A2 (enExample) |
| CA (1) | CA3218815A1 (enExample) |
| CL (1) | CL2023003505A1 (enExample) |
| CO (1) | CO2023016058A2 (enExample) |
| IL (1) | IL308883A (enExample) |
| MX (1) | MX2023014026A (enExample) |
| PE (1) | PE20250265A1 (enExample) |
| TW (1) | TW202313068A (enExample) |
| WO (1) | WO2022251394A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024158905A1 (en) * | 2023-01-24 | 2024-08-02 | Ohio State Innovation Foundation | Muc5ac in pancreatic ductal adenocarcinoma |
| WO2025128462A1 (en) * | 2023-12-12 | 2025-06-19 | Eli Lilly And Company | Novel therapeutic delivery moieties and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998203A (en) | 1996-04-16 | 1999-12-07 | Ribozyme Pharmaceuticals, Inc. | Enzymatic nucleic acids containing 5'-and/or 3'-cap structures |
| JP2002537828A (ja) | 1999-03-10 | 2002-11-12 | フォゲン リミティド | 細胞への物質のデリバリー |
| JP2006507841A (ja) * | 2002-11-14 | 2006-03-09 | ダーマコン， インコーポレイテッド | 機能的ｓｉＲＮＡおよび超機能的ｓｉＲＮＡ |
| EP2412826B1 (en) * | 2004-05-07 | 2014-01-08 | Celera Corporation | Genetic polymorphism associated with liver fibrosis methods of detection and uses thereof |
| BRPI0715375A2 (pt) | 2006-08-18 | 2013-06-18 | Hoffmann La Roche | policonjugados para distribuiÇço in vivo de polinucleotÍdeos |
| EP2377934A4 (en) * | 2008-12-12 | 2012-09-26 | Kureha Corp | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF TUMOR AND ASTHMA |
| EP3023495B1 (en) | 2010-02-24 | 2019-05-08 | Arrowhead Pharmaceuticals, Inc. | Compositions for targeted delivery of sirna |
| WO2012040617A2 (en) * | 2010-09-23 | 2012-03-29 | Neogenix Oncology, Inc. | Colon and pancreas cancer peptidomimetics |
| US9920317B2 (en) * | 2010-11-12 | 2018-03-20 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
| US8501930B2 (en) | 2010-12-17 | 2013-08-06 | Arrowhead Madison Inc. | Peptide-based in vivo siRNA delivery system |
| KR20140051357A (ko) | 2011-08-26 | 2014-04-30 | 애로우헤드 리서치 코오포레이션 | Ｉｎ Ｖｉｖｏ 핵산 전달용 폴리(비닐 에스테르) 고분자 |
| AU2012377385A1 (en) | 2012-04-18 | 2014-01-23 | Arrowhead Research Corporation | Poly(acrylate) polymers for in vivo nucleic acid delivery |
| US9452228B2 (en) * | 2013-04-01 | 2016-09-27 | Immunomedics, Inc. | Antibodies reactive with an epitope located in the N-terminal region of MUC5AC comprising cysteine-rich subdomain 2 (Cys2) |
| WO2016003869A1 (en) * | 2014-06-30 | 2016-01-07 | Immunomedics, Inc. | Antibodies reactive with an epitope located in the n-terminal region of muc5ac comprising cysteine-rich subdomain 2 (cys2) |
| CA3023764A1 (en) | 2016-06-06 | 2017-12-14 | Arrowhead Pharmaceuticals, Inc. | 5'-cyclo-phosphonate modified nucleotides |
| JOP20190015A1 (ar) * | 2016-08-04 | 2019-02-04 | Arrowhead Pharmaceuticals Inc | عوامل (ار ان ايه آي) لعدوى فيروس الالتهاب الكبدي الوبائي ب |
| CN109952376B (zh) | 2016-11-01 | 2023-09-05 | 箭头药业股份有限公司 | αvβ6整联蛋白配体及其应用 |
| KR102762143B1 (ko) | 2017-11-01 | 2025-02-07 | 애로우헤드 파마슈티컬스 인코포레이티드 | 인테그린 리간드 및 그의 용도 |
| CA3089276A1 (en) | 2018-02-17 | 2019-08-22 | Arrowhead Pharmaceuticals, Inc. | Trialkyne linking agents and methods of use |
| US11040056B2 (en) * | 2018-05-11 | 2021-06-22 | The University Of North Carolina At Chapel Hill | Benzimidazoles that enhance the activity of oligonucleotides |
-
2022
- 2022-05-25 KR KR1020237044563A patent/KR20240014067A/ko active Pending
- 2022-05-25 MX MX2023014026A patent/MX2023014026A/es unknown
- 2022-05-25 US US17/824,841 patent/US12365897B2/en active Active
- 2022-05-25 PE PE2023003126A patent/PE20250265A1/es unknown
- 2022-05-25 JP JP2023573300A patent/JP2024520522A/ja active Pending
- 2022-05-25 CN CN202280052248.5A patent/CN117858949A/zh active Pending
- 2022-05-25 AU AU2022280863A patent/AU2022280863A1/en active Pending
- 2022-05-25 CA CA3218815A patent/CA3218815A1/en active Pending
- 2022-05-25 BR BR112023024615A patent/BR112023024615A2/pt not_active Application Discontinuation
- 2022-05-25 IL IL308883A patent/IL308883A/en unknown
- 2022-05-25 EP EP22812096.0A patent/EP4352229A4/en active Pending
- 2022-05-25 WO PCT/US2022/030969 patent/WO2022251394A1/en not_active Ceased
- 2022-05-27 TW TW111119839A patent/TW202313068A/zh unknown
-
2023
- 2023-11-23 CO CONC2023/0016058A patent/CO2023016058A2/es unknown
- 2023-11-24 CL CL2023003505A patent/CL2023003505A1/es unknown
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