JP2024517903A5 - - Google Patents
Info
- Publication number
- JP2024517903A5 JP2024517903A5 JP2023568675A JP2023568675A JP2024517903A5 JP 2024517903 A5 JP2024517903 A5 JP 2024517903A5 JP 2023568675 A JP2023568675 A JP 2023568675A JP 2023568675 A JP2023568675 A JP 2023568675A JP 2024517903 A5 JP2024517903 A5 JP 2024517903A5
- Authority
- JP
- Japan
- Prior art keywords
- arginine
- methyl
- composition
- thiocitrulline
- nio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163186389P | 2021-05-10 | 2021-05-10 | |
| US63/186,389 | 2021-05-10 | ||
| PCT/IL2022/050486 WO2022239001A1 (en) | 2021-05-10 | 2022-05-10 | Pharmaceutical compositions for treating neurological conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024517903A JP2024517903A (ja) | 2024-04-23 |
| JP2024517903A5 true JP2024517903A5 (enExample) | 2025-05-20 |
Family
ID=81846510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023568675A Pending JP2024517903A (ja) | 2021-05-10 | 2022-05-10 | 神経学的状態を治療するための薬学的組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20240316006A1 (enExample) |
| EP (1) | EP4337197A1 (enExample) |
| JP (1) | JP2024517903A (enExample) |
| KR (1) | KR20240017813A (enExample) |
| AU (1) | AU2022272489A1 (enExample) |
| BR (1) | BR112023023486A2 (enExample) |
| CA (1) | CA3217972A1 (enExample) |
| IL (1) | IL308282A (enExample) |
| MX (1) | MX2023013202A (enExample) |
| WO (1) | WO2022239001A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024224296A2 (en) * | 2023-04-24 | 2024-10-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Targeted pharmaceutical compositions to treat neurological conditions |
| WO2024231899A1 (en) * | 2023-05-10 | 2024-11-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Compounds for nos-related cancers and methods of use |
| WO2025096244A1 (en) * | 2023-10-30 | 2025-05-08 | Olfera Corporation | Olfactory delivery scaffolds and methods for making and using same |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US5549910A (en) | 1989-03-31 | 1996-08-27 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
| US5252334A (en) | 1989-09-08 | 1993-10-12 | Cygnus Therapeutic Systems | Solid matrix system for transdermal drug delivery |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| JP3218637B2 (ja) | 1990-07-26 | 2001-10-15 | 大正製薬株式会社 | 安定なリポソーム水懸濁液 |
| JP2958076B2 (ja) | 1990-08-27 | 1999-10-06 | 株式会社ビタミン研究所 | 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法 |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5741516A (en) | 1994-06-20 | 1998-04-21 | Inex Pharmaceuticals Corporation | Sphingosomes for enhanced drug delivery |
| WO1996021445A1 (en) * | 1995-01-13 | 1996-07-18 | The General Hospital Corporation | Methods of inhibiting neurodegenerative diseases |
| US5795587A (en) | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
| US5697899A (en) | 1995-02-07 | 1997-12-16 | Gensia | Feedback controlled drug delivery system |
| US5738868A (en) | 1995-07-18 | 1998-04-14 | Lipogenics Ltd. | Liposome compositions and kits therefor |
| US5656016A (en) | 1996-03-18 | 1997-08-12 | Abbott Laboratories | Sonophoretic drug delivery system |
| US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
| US5783208A (en) | 1996-07-19 | 1998-07-21 | Theratech, Inc. | Transdermal drug delivery matrix for coadministering estradiol and another steroid |
| US5779708A (en) | 1996-08-15 | 1998-07-14 | Cyberdent, Inc. | Intraosseous drug delivery device and method |
| US6774279B2 (en) | 1997-05-30 | 2004-08-10 | Carnegie Institution Of Washington | Use of FLP recombinase in mice |
| GB9818110D0 (en) | 1998-08-19 | 1998-10-14 | Weston Medical Ltd | Needleless injectors and other devices |
| US6096002A (en) | 1998-11-18 | 2000-08-01 | Bioject, Inc. | NGAS powered self-resetting needle-less hypodermic jet injection apparatus and method |
| US7749539B2 (en) | 2000-11-30 | 2010-07-06 | Efrat Biopolymers Ltd. | Polymeric formulations for drug delivery |
| WO2003080809A2 (en) | 2002-03-21 | 2003-10-02 | Sangamo Biosciences, Inc. | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| EP2806025B1 (en) | 2002-09-05 | 2019-04-03 | California Institute of Technology | Use of zinc finger nucleases to stimulate gene targeting |
| WO2004064737A2 (en) | 2003-01-17 | 2004-08-05 | Alnylam Pharmaceuticals | Therapeutics compositions |
| ES2702942T3 (es) | 2003-04-17 | 2019-03-06 | Alnylam Pharmaceuticals Inc | Agentes de ARNi modificados |
| JP4991288B2 (ja) | 2003-04-17 | 2012-08-01 | アルナイラム ファーマシューティカルズ, インコーポレイテッド | 二本鎖iRNA剤、および二本鎖iRNA剤の対合の安定性を調節する方法。 |
| US20060014264A1 (en) | 2004-07-13 | 2006-01-19 | Stowers Institute For Medical Research | Cre/lox system with lox sites having an extended spacer region |
| ES2582091T3 (es) | 2005-10-18 | 2016-09-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| EP2067402A1 (en) | 2007-12-07 | 2009-06-10 | Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; | Transponson-mediated mutagenesis in spermatogonial stem cells |
| UA105182C2 (ru) * | 2008-07-03 | 2014-04-25 | Ньюрексон, Інк. | Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность |
| US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
| US20150030576A1 (en) | 2012-01-10 | 2015-01-29 | Moderna Therapeutics, Inc. | Methods and compositions for targeting agents into and across the blood-brain barrier |
| WO2013126963A1 (en) | 2012-02-29 | 2013-09-06 | Benitec Biopharma Limited | Pain treatment |
| CN109554350B (zh) | 2012-11-27 | 2022-09-23 | 儿童医疗中心有限公司 | 用于胎儿血红蛋白再诱导的靶向bcl11a远端调控元件 |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| KR20150103280A (ko) | 2013-01-08 | 2015-09-09 | 베니텍 바이오파마 리미티드 | 연령-관련 황반 변성 치료 |
| US10569097B2 (en) | 2015-07-28 | 2020-02-25 | Photonmd, Inc. | Systems and methods for phototherapeutic modulation of nitric oxide |
| FI130359B (fi) | 2018-05-21 | 2023-07-20 | Valmet Technologies Oy | Leijupetikattilaksi soveltuva koaksiaalinen lämmönsiirtoputki ja menetelmä sen valmistamiseksi |
-
2022
- 2022-05-10 JP JP2023568675A patent/JP2024517903A/ja active Pending
- 2022-05-10 EP EP22725570.0A patent/EP4337197A1/en active Pending
- 2022-05-10 BR BR112023023486A patent/BR112023023486A2/pt unknown
- 2022-05-10 US US18/290,220 patent/US20240316006A1/en active Pending
- 2022-05-10 AU AU2022272489A patent/AU2022272489A1/en active Pending
- 2022-05-10 IL IL308282A patent/IL308282A/en unknown
- 2022-05-10 MX MX2023013202A patent/MX2023013202A/es unknown
- 2022-05-10 KR KR1020237041932A patent/KR20240017813A/ko active Pending
- 2022-05-10 WO PCT/IL2022/050486 patent/WO2022239001A1/en not_active Ceased
- 2022-05-10 CA CA3217972A patent/CA3217972A1/en active Pending
-
2025
- 2025-04-08 US US19/173,097 patent/US20250255850A1/en active Pending
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