JP2024517340A5 - - Google Patents
Info
- Publication number
- JP2024517340A5 JP2024517340A5 JP2023570190A JP2023570190A JP2024517340A5 JP 2024517340 A5 JP2024517340 A5 JP 2024517340A5 JP 2023570190 A JP2023570190 A JP 2023570190A JP 2023570190 A JP2023570190 A JP 2023570190A JP 2024517340 A5 JP2024517340 A5 JP 2024517340A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- substituted
- compound
- formula
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2021/054167 WO2022238737A1 (en) | 2021-05-14 | 2021-05-14 | Compounds for degrading alpha-synuclein aggregates and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024517340A JP2024517340A (ja) | 2024-04-19 |
| JP2024517340A5 true JP2024517340A5 (https=) | 2024-05-21 |
Family
ID=76034924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023570190A Pending JP2024517340A (ja) | 2021-05-14 | 2021-05-14 | アルファ－シヌクレイン凝集物を分解する化合物及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4337259A1 (https=) |
| JP (1) | JP2024517340A (https=) |
| KR (1) | KR20240008335A (https=) |
| CN (1) | CN117377496A (https=) |
| AU (1) | AU2021444937A1 (https=) |
| CA (1) | CA3218573A1 (https=) |
| TW (1) | TW202304516A (https=) |
| WO (1) | WO2022238737A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025162452A1 (zh) * | 2024-01-29 | 2025-08-07 | 思努赛生物科技(上海)有限责任公司 | 一种识别α-突触核蛋白聚集体的化合物及其用途 |
| CN118845735A (zh) * | 2024-06-21 | 2024-10-29 | 合肥综合性国家科学中心大健康研究院 | 金刚烷衍生物在制备离子通道tmem175激动剂中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10300155B2 (en) * | 2015-12-31 | 2019-05-28 | Washington University | Alpha-synuclein ligands |
| MX2019005007A (es) | 2016-11-01 | 2019-07-18 | Arvinas Inc | Protac dirigidos a la proteína tau y métodos asociados de uso. |
| ES2965049T3 (es) | 2017-07-12 | 2024-04-10 | Dana Farber Cancer Inst Inc | Compuestos para la degradación de la proteína tau |
| TW201946624A (zh) | 2018-05-09 | 2019-12-16 | 新旭生技股份有限公司 | 雜芳基化合物及其用途 |
| JP7297053B2 (ja) * | 2018-08-20 | 2023-06-23 | アルビナス・オペレーションズ・インコーポレイテッド | 神経変性疾患を治療するためのｅ３ユビキチンリガーゼ結合活性を有するキメラ（ｐｒｏｔａｃ）化合物を標的とし、アルファ－シヌクレインタンパク質を標的とするタンパク質分解 |
| PH12022500002A1 (en) * | 2019-06-28 | 2023-04-03 | Kymera Therapeutics Inc | Irak degraders and uses thereof |
-
2021
- 2021-05-14 EP EP21726997.6A patent/EP4337259A1/en active Pending
- 2021-05-14 KR KR1020237042637A patent/KR20240008335A/ko active Pending
- 2021-05-14 AU AU2021444937A patent/AU2021444937A1/en not_active Abandoned
- 2021-05-14 CA CA3218573A patent/CA3218573A1/en active Pending
- 2021-05-14 CN CN202180098221.5A patent/CN117377496A/zh active Pending
- 2021-05-14 JP JP2023570190A patent/JP2024517340A/ja active Pending
- 2021-05-14 WO PCT/IB2021/054167 patent/WO2022238737A1/en not_active Ceased
-
2022
- 2022-05-13 TW TW111118050A patent/TW202304516A/zh unknown
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