JP2024516308A5 - - Google Patents
Info
- Publication number
- JP2024516308A5 JP2024516308A5 JP2023568054A JP2023568054A JP2024516308A5 JP 2024516308 A5 JP2024516308 A5 JP 2024516308A5 JP 2023568054 A JP2023568054 A JP 2023568054A JP 2023568054 A JP2023568054 A JP 2023568054A JP 2024516308 A5 JP2024516308 A5 JP 2024516308A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- region
- acid sequence
- mage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163184183P | 2021-05-04 | 2021-05-04 | |
| US63/184,183 | 2021-05-04 | ||
| US202163239293P | 2021-08-31 | 2021-08-31 | |
| US63/239,293 | 2021-08-31 | ||
| PCT/US2022/027463 WO2022235662A1 (en) | 2021-05-04 | 2022-05-03 | Chimeric antigen receptors with mage-a4 specificity and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024516308A JP2024516308A (ja) | 2024-04-12 |
| JP2024516308A5 true JP2024516308A5 (https=) | 2025-05-14 |
Family
ID=81750592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023568054A Pending JP2024516308A (ja) | 2021-05-04 | 2022-05-03 | Ｍａｇｅ－ａ４特異性を有するキメラ抗原受容体及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240226163A1 (https=) |
| EP (1) | EP4333876A1 (https=) |
| JP (1) | JP2024516308A (https=) |
| KR (1) | KR20240005854A (https=) |
| AU (1) | AU2022271212A1 (https=) |
| BR (1) | BR112023023067A2 (https=) |
| CA (1) | CA3217914A1 (https=) |
| CL (1) | CL2023003282A1 (https=) |
| CO (1) | CO2023016595A2 (https=) |
| IL (1) | IL308231A (https=) |
| MX (1) | MX2023013075A (https=) |
| WO (1) | WO2022235662A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2023010541A (es) | 2021-03-09 | 2023-11-24 | Cdr Life Ag | Proteinas de union al antigeno del peptido del mhc mage-a4. |
| US12435444B2 (en) | 2021-03-09 | 2025-10-07 | Cdr-Life Ag | Rabbit-derived antigen binding protein nucleic acid libraries and methods of making the same |
| CA3264474A1 (en) | 2022-09-14 | 2024-03-21 | Cdr-Life Ag | MAGE-A4 DOUBLE T LYMPHOCYTE ENGAGEMENT |
| US20250144200A1 (en) | 2023-11-06 | 2025-05-08 | Novavax, Inc. | Intranasal immunogenic compositions |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| IL79289A (en) | 1985-07-05 | 1992-01-15 | Whitehead Biomedical Inst | Introduction and expression of foreign genetic material into keratinocytes using a recombinant retrovirus |
| US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| ATE117375T1 (de) | 1987-09-11 | 1995-02-15 | Whitehead Biomedical Inst | Transduktionsveränderte fibroblasten und ihre anwendung. |
| JP2914692B2 (ja) | 1987-12-11 | 1999-07-05 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 内皮細胞の遺伝子修飾 |
| WO1989007136A2 (en) | 1988-02-05 | 1989-08-10 | Whitehead Institute For Biomedical Research | Modified hepatocytes and uses therefor |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| ES2096750T3 (es) | 1990-10-31 | 1997-03-16 | Somatix Therapy Corp | Vectores retroviricos utiles para la terapia genica. |
| US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| KR20030032922A (ko) | 2000-02-24 | 2003-04-26 | 싸이트 테라피스 인코포레이티드 | 세포의 동시 자극 및 농축 |
| US20030170238A1 (en) | 2002-03-07 | 2003-09-11 | Gruenberg Micheal L. | Re-activated T-cells for adoptive immunotherapy |
| JP5307708B2 (ja) | 2006-06-02 | 2013-10-02 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | ヒトｉｌ−６受容体に対する高親和性抗体 |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| US9987308B2 (en) | 2011-03-23 | 2018-06-05 | Fred Hutchinson Cancer Research Center | Method and compositions for cellular immunotherapy |
| BR112014029417B1 (pt) | 2012-05-25 | 2023-03-07 | Cellectis | Método ex vivo para a preparação de células t para imunoterapia |
| NL2014935B1 (en) * | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
| EP4004049A1 (en) * | 2019-07-24 | 2022-06-01 | Regeneron Pharmaceuticals, Inc. | Chimeric antigen receptors with mage-a4 specificity and uses thereof |
| US12077603B2 (en) * | 2019-08-15 | 2024-09-03 | Regeneron Pharmaceuticals, Inc. | Multispecific antigen-binding molecules for cell targeting and uses thereof |
| KR20230025662A (ko) * | 2020-05-05 | 2023-02-22 | 리제너론 파마슈티칼스 인코포레이티드 | Cd28 제타 및 cd3 제타를 포함하는 car |
-
2022
- 2022-05-03 AU AU2022271212A patent/AU2022271212A1/en active Pending
- 2022-05-03 US US18/559,009 patent/US20240226163A1/en active Pending
- 2022-05-03 WO PCT/US2022/027463 patent/WO2022235662A1/en not_active Ceased
- 2022-05-03 IL IL308231A patent/IL308231A/en unknown
- 2022-05-03 EP EP22725057.8A patent/EP4333876A1/en active Pending
- 2022-05-03 CA CA3217914A patent/CA3217914A1/en active Pending
- 2022-05-03 MX MX2023013075A patent/MX2023013075A/es unknown
- 2022-05-03 BR BR112023023067A patent/BR112023023067A2/pt unknown
- 2022-05-03 JP JP2023568054A patent/JP2024516308A/ja active Pending
- 2022-05-03 KR KR1020237041692A patent/KR20240005854A/ko active Pending
-
2023
- 2023-11-03 CL CL2023003282A patent/CL2023003282A1/es unknown
- 2023-11-30 CO CONC2023/0016595A patent/CO2023016595A2/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7781243B2 (ja) | ガイダンス及びナビゲーションコントロール蛋白質並びにその生産及び使用方法 | |
| KR102777002B1 (ko) | 항글리피칸-3 항체 및 이의 응용 | |
| JP2022542559A5 (https=) | ||
| JP7091447B2 (ja) | 新型なｓｃＦｖアミノ酸配列、それを含むキメラ抗原受容体、およびその使用 | |
| AU2022204181A1 (en) | Chimeric antigen receptors targeting B-cell maturation antigen and uses thereof | |
| CN112912401B (zh) | 抗-l1细胞粘附分子抗体或其抗原结合片段及包含其的嵌合抗原受体 | |
| JP2021531004A5 (https=) | ||
| JP2024516308A5 (https=) | ||
| CA3032054A1 (en) | Combination therapies of chimeric antigen receptors and pd-1 inhibitors | |
| CN111465616B (zh) | 特异性识别恶性b细胞的抗体或其抗原结合片段、包含其的嵌合抗原受体及其用途 | |
| IL252621B1 (en) | G-protein receptor-directed chimeric antigen receptors and their use | |
| KR102316091B1 (ko) | Bcma를 표적으로 하는 키메라 항원 수용체 및 이의 용도 | |
| EP3227436A1 (en) | Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof | |
| WO2022247795A1 (zh) | 靶向Claudin18.2的纳米抗体及其用途 | |
| CN116744948A (zh) | 包含t细胞抗原偶联物的细胞及其用途 | |
| KR20230005001A (ko) | 메소텔린 특이적 항체 및 이의 용도 | |
| WO2022057875A1 (zh) | 靶向4-1bb的单域抗体、其融合蛋白、药物组合物及用途 | |
| CA3205830A1 (en) | Prostate cancer chimeric antigen receptors | |
| CN113825772B (zh) | 抗her2亲合体及将其用作开关分子的可切换嵌合抗原受体 | |
| TW202309091A (zh) | 嵌合受體及其使用方法 | |
| TW202313687A (zh) | Ｇｐｃ３結合分子 | |
| CN111542541A (zh) | 特异性识别恶性b细胞的抗体或其抗原结合片段、包含其的嵌合抗原受体及其用途 | |
| KR20220122844A (ko) | Cd22에 특이적인 인간화 항체 및 이의 용도 | |
| CN115873115A (zh) | 一种抗4-1bb单克隆抗体在肿瘤免疫治疗上的应用 | |
| WO2025103456A1 (en) | Gprc5d-binding moieties, chimeric antigen receptors and uses thereof |