JP2024515576A5 - - Google Patents

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Publication number
JP2024515576A5
JP2024515576A5 JP2023562187A JP2023562187A JP2024515576A5 JP 2024515576 A5 JP2024515576 A5 JP 2024515576A5 JP 2023562187 A JP2023562187 A JP 2023562187A JP 2023562187 A JP2023562187 A JP 2023562187A JP 2024515576 A5 JP2024515576 A5 JP 2024515576A5
Authority
JP
Japan
Prior art keywords
aptamer
ome
target
complex
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023562187A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024515576A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/024361 external-priority patent/WO2022221241A1/en
Publication of JP2024515576A publication Critical patent/JP2024515576A/ja
Publication of JP2024515576A5 publication Critical patent/JP2024515576A5/ja
Pending legal-status Critical Current

Links

JP2023562187A 2021-04-13 2022-04-12 修飾ヌクレオシド Pending JP2024515576A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163174495P 2021-04-13 2021-04-13
US63/174,495 2021-04-13
US202163174792P 2021-04-14 2021-04-14
US63/174,792 2021-04-14
PCT/US2022/024361 WO2022221241A1 (en) 2021-04-13 2022-04-12 Modified nucleosides

Publications (2)

Publication Number Publication Date
JP2024515576A JP2024515576A (ja) 2024-04-10
JP2024515576A5 true JP2024515576A5 (enExample) 2025-04-11

Family

ID=81392588

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023562187A Pending JP2024515576A (ja) 2021-04-13 2022-04-12 修飾ヌクレオシド

Country Status (8)

Country Link
US (1) US20250283094A1 (enExample)
EP (1) EP4323374A1 (enExample)
JP (1) JP2024515576A (enExample)
KR (1) KR20230170688A (enExample)
AU (1) AU2022258298A1 (enExample)
CA (1) CA3214113A1 (enExample)
MX (1) MX2023012081A (enExample)
WO (1) WO2022221241A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240139119A (ko) * 2023-03-09 2024-09-23 주식회사 압타머사이언스 티미딘으로부터 개질된 뉴클레오시드의 제조방법
EP4739992A1 (en) 2023-07-06 2026-05-13 SomaLogic Operating Co., Inc. Detection of target molecules in dried biologic matrices
WO2025235440A1 (en) 2024-05-07 2025-11-13 Somalogic Operating Co., Inc. Nucleic acid translator gates for protein measurement
WO2026064275A1 (en) 2024-09-20 2026-03-26 Somalogic, Inc. Methods for detection of proteins and nucleic acids
WO2026064276A1 (en) 2024-09-20 2026-03-26 Somalogic, Inc. Methods for detection of proteins and nucleic acids

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580737A (en) 1990-06-11 1996-12-03 Nexstar Pharmaceuticals, Inc. High-affinity nucleic acid ligands that discriminate between theophylline and caffeine
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US5705337A (en) 1990-06-11 1998-01-06 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chemi-SELEX
KR970002255B1 (ko) 1990-06-11 1997-02-26 넥스스타 파아마슈티컬드, 인크. 핵산 리간드
GB2341189B (en) * 1998-08-31 2001-06-13 Amersham Pharm Biotech Inc Energy transfer dyes
US6110462A (en) * 1999-03-03 2000-08-29 The Scripps Research Institute Enzymatic DNA molecules that contain modified nucleotides
US6376190B1 (en) 2000-09-22 2002-04-23 Somalogic, Inc. Modified SELEX processes without purified protein
GB0326073D0 (en) * 2003-11-07 2003-12-10 Solexa Ltd Improvements in or relating to polynucleotide arrays
EP2613147B1 (en) * 2006-01-17 2015-03-11 Somalogic, Inc. Detection methods using aptamers
US7855054B2 (en) 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
DK2172566T4 (da) 2007-07-17 2022-06-13 Somalogic Inc Fremgangsmåde til generering af aptamerer med forbedrede off-rates
WO2018034987A1 (en) * 2016-08-19 2018-02-22 The Johns Hopkins University Dna polymerase beta inhibitors

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