JP2024514203A5 - - Google Patents

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Publication number
JP2024514203A5
JP2024514203A5 JP2023563211A JP2023563211A JP2024514203A5 JP 2024514203 A5 JP2024514203 A5 JP 2024514203A5 JP 2023563211 A JP2023563211 A JP 2023563211A JP 2023563211 A JP2023563211 A JP 2023563211A JP 2024514203 A5 JP2024514203 A5 JP 2024514203A5
Authority
JP
Japan
Prior art keywords
icd
zeta signaling
cells
dap12
signaling domains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023563211A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024514203A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/024842 external-priority patent/WO2022221548A1/en
Publication of JP2024514203A publication Critical patent/JP2024514203A/ja
Publication of JP2024514203A5 publication Critical patent/JP2024514203A5/ja
Pending legal-status Critical Current

Links

JP2023563211A 2021-04-14 2022-04-14 Cd5陽性がんを標的とするキメラ抗原受容体 Pending JP2024514203A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163174990P 2021-04-14 2021-04-14
US63/174,990 2021-04-14
PCT/US2022/024842 WO2022221548A1 (en) 2021-04-14 2022-04-14 Chimeric antigen receptors to target cd5-positive cancers

Publications (2)

Publication Number Publication Date
JP2024514203A JP2024514203A (ja) 2024-03-28
JP2024514203A5 true JP2024514203A5 (https=) 2025-02-21

Family

ID=83640731

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023563211A Pending JP2024514203A (ja) 2021-04-14 2022-04-14 Cd5陽性がんを標的とするキメラ抗原受容体

Country Status (11)

Country Link
US (1) US20240189357A1 (https=)
EP (1) EP4322992A4 (https=)
JP (1) JP2024514203A (https=)
KR (1) KR20240007911A (https=)
CN (1) CN117480187A (https=)
AU (1) AU2022259658A1 (https=)
BR (1) BR112023021133A2 (https=)
CA (1) CA3216557A1 (https=)
IL (1) IL307408A (https=)
MX (1) MX2023012180A (https=)
WO (1) WO2022221548A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102831183B1 (ko) * 2021-04-29 2025-07-09 한국생명공학연구원 신규한 항-cd5 키메릭 항원 수용체 및 이를 발현하는 면역세포
EP4419128A4 (en) * 2021-10-20 2025-10-01 Univ Texas NK CELL ENGINEERING WITH CAR CONSTRUCTION WITH OPTIMAL SIGNALING
JP2024539129A (ja) * 2021-10-21 2024-10-28 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 増強された代謝適合性を有する治療用免疫細胞の製造方法およびその組成物
WO2024249728A2 (en) * 2023-06-02 2024-12-05 Board Of Regents, The University Of Texas System Selection of cryopreserved cord blood units for the manufacture of natural killer cells with enhanced potency
WO2025038813A1 (en) * 2023-08-16 2025-02-20 Beam Therapeutics Inc. Cd5-binding polypeptides, compositions comprising the same, and methods for use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7237449B2 (ja) * 2015-02-27 2023-03-13 アイセル・ジーン・セラピューティクス・エルエルシー 血液系腫瘍を標的としたキメラ抗体受容体(CARs)の構成およびその使用方法
US10786549B2 (en) * 2015-04-23 2020-09-29 Baylor College Of Medicine CD5 chimeric antigen receptor for adoptive T cell therapy
AU2016274989A1 (en) * 2015-06-12 2017-11-02 Immunomedics, Inc. Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
WO2017112877A1 (en) * 2015-12-22 2017-06-29 Icell Gene Therapeutics, Llc Chimeric antigen receptors and enhancement of anti-tumor activity
EP3567101A4 (en) * 2017-01-05 2020-12-02 Korea Research Institute of Bioscience and Biotechnology NATURAL KILLER CELL EXPRESSING AN ANTI-COTININ CHEMERIC ANTIGEN RECEPTOR
CA3070998A1 (en) * 2017-07-25 2019-01-31 Board Of Regents, The University Of Texas System Enhanced chimeric antigen receptors and use thereof
US20230159618A1 (en) * 2017-07-25 2023-05-25 Board Of Regents, The University Of Texas System Enhanced chimeric antigen receptors and use thereof

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