JP2024508223A - 免疫細胞を形質導入する方法 - Google Patents

免疫細胞を形質導入する方法 Download PDF

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JP2024508223A
JP2024508223A JP2023544092A JP2023544092A JP2024508223A JP 2024508223 A JP2024508223 A JP 2024508223A JP 2023544092 A JP2023544092 A JP 2023544092A JP 2023544092 A JP2023544092 A JP 2023544092A JP 2024508223 A JP2024508223 A JP 2024508223A
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cells
cell
cell population
starting
transduction
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JP2024508223A5 (https=
JPWO2022165133A5 (https=
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トッド ルーマン
ホセルヒオ サラゴサ
アブラハム ジャーマンズデルファー
スマ ラオ
ヤジン ニ
チュペイ チャン
トム タオ フアン
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アロジーン セラピューティクス，インコーポレイテッド
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C12N2740/00—Reverse transcribing RNA viruses
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    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • General Chemical & Material Sciences (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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JP2023544092A 2021-01-28 2022-01-28 免疫細胞を形質導入する方法 Pending JP2024508223A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163142730P 2021-01-28 2021-01-28
US63/142,730 2021-01-28
US202263302225P 2022-01-24 2022-01-24
US63/302,225 2022-01-24
PCT/US2022/014247 WO2022165133A1 (en) 2021-01-28 2022-01-28 Methods for transducing immune cells

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JP2024508223A true JP2024508223A (ja) 2024-02-26
JP2024508223A5 JP2024508223A5 (https=) 2025-02-04
JPWO2022165133A5 JPWO2022165133A5 (https=) 2025-02-04

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US (2) US12365873B2 (https=)
EP (1) EP4284937A1 (https=)
JP (1) JP2024508223A (https=)
KR (1) KR20230135593A (https=)
AU (1) AU2022212090A1 (https=)
CA (1) CA3204357A1 (https=)
IL (1) IL303847A (https=)
MX (1) MX2023008662A (https=)
TW (1) TW202246517A (https=)
WO (1) WO2022165133A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012533299A (ja) * 2009-07-15 2012-12-27 カリミューン， インコーポレーティッド ヒト免疫不全ウイルス阻害のための二重ベクター
JP2018531026A (ja) * 2015-10-20 2018-10-25 カイト ファーマ インコーポレイテッドＫｉｔｅ Ｐｈａｒｍａ， Ｉｎｃ Ｔ細胞療法用のｔ細胞を調製する方法
JP2019509063A (ja) * 2016-03-19 2019-04-04 エフ１ オンコロジー，インコーポレイティド リンパ球に形質導入を行うための方法及び組成物、並びにその制御された増加
JP2019516352A (ja) * 2016-04-01 2019-06-20 アムジエン・インコーポレーテツド Ｆｌｔ３に対するキメラ受容体及びその使用方法

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IL104570A0 (en) 1992-03-18 1993-05-13 Yeda Res & Dev Chimeric genes and cells transformed therewith
US5827642A (en) 1994-08-31 1998-10-27 Fred Hutchinson Cancer Research Center Rapid expansion method ("REM") for in vitro propagation of T lymphocytes
US6867041B2 (en) 2000-02-24 2005-03-15 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
CA2406864A1 (en) 2000-02-24 2001-08-30 Life Technologies Corporation Simultaneous stimulation and concentration of cells
US6797514B2 (en) 2000-02-24 2004-09-28 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
MXPA05000511A (es) 2001-07-12 2005-09-30 Jefferson Foote Anticuepros super humanizados.
WO2011146862A1 (en) 2010-05-21 2011-11-24 Bellicum Pharmaceuticals, Inc. Methods for inducing selective apoptosis
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
CN110200997A (zh) 2011-03-23 2019-09-06 弗雷德哈钦森癌症研究中心 用于细胞免疫治疗的方法和组合物
CN103316356B (zh) 2012-03-22 2016-08-17 北京三诺佳邑生物技术有限责任公司 一种重组慢病毒载体制剂
GB201206559D0 (en) 2012-04-13 2012-05-30 Ucl Business Plc Polypeptide
FR3010720B1 (fr) 2013-09-16 2017-08-11 Genethon Procede de production de virus enveloppes
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JP2017505819A (ja) 2014-02-04 2017-02-23 カイト ファーマ インコーポレイテッドＫｉｔｅ Ｐｈａｒｍａ， Ｉｎｃ Ｂ細胞悪性腫瘍及び他のがんの治療に有用な自己ｔ細胞を産生する方法、並びにその組成物
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JP2018531026A (ja) * 2015-10-20 2018-10-25 カイト ファーマ インコーポレイテッドＫｉｔｅ Ｐｈａｒｍａ， Ｉｎｃ Ｔ細胞療法用のｔ細胞を調製する方法
JP2019509063A (ja) * 2016-03-19 2019-04-04 エフ１ オンコロジー，インコーポレイティド リンパ球に形質導入を行うための方法及び組成物、並びにその制御された増加
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IL303847A (en) 2023-08-01
TW202246517A (zh) 2022-12-01
US20260009000A1 (en) 2026-01-08
US12365873B2 (en) 2025-07-22
EP4284937A1 (en) 2023-12-06
WO2022165133A1 (en) 2022-08-04
CA3204357A1 (en) 2022-08-04
MX2023008662A (es) 2023-08-01
AU2022212090A1 (en) 2023-07-06
US20220249556A1 (en) 2022-08-11
KR20230135593A (ko) 2023-09-25

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