JP2024507394A5 - - Google Patents
Info
- Publication number
- JP2024507394A5 JP2024507394A5 JP2023551966A JP2023551966A JP2024507394A5 JP 2024507394 A5 JP2024507394 A5 JP 2024507394A5 JP 2023551966 A JP2023551966 A JP 2023551966A JP 2023551966 A JP2023551966 A JP 2023551966A JP 2024507394 A5 JP2024507394 A5 JP 2024507394A5
- Authority
- JP
- Japan
- Prior art keywords
- suspension formulation
- aerosol
- nanoparticles
- formulation according
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21159455.1 | 2021-02-26 | ||
| EP21159455 | 2021-02-26 | ||
| PCT/EP2022/054796 WO2022180213A1 (en) | 2021-02-26 | 2022-02-25 | Formulations for aerosol formation and aerosols for the delivery of nucleic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024507394A JP2024507394A (ja) | 2024-02-19 |
| JP2024507394A5 true JP2024507394A5 (https=) | 2025-03-05 |
Family
ID=74797735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023551966A Pending JP2024507394A (ja) | 2021-02-26 | 2022-02-25 | エアロゾル形成用の製剤および核酸を送達するためのエアロゾル |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240156729A1 (https=) |
| EP (1) | EP4297722A1 (https=) |
| JP (1) | JP2024507394A (https=) |
| KR (1) | KR20230152014A (https=) |
| CN (1) | CN116887812A (https=) |
| AU (1) | AU2022226409A1 (https=) |
| BR (1) | BR112023016903A2 (https=) |
| CA (1) | CA3209032A1 (https=) |
| IL (1) | IL305353A (https=) |
| MX (1) | MX2023009757A (https=) |
| WO (1) | WO2022180213A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024042236A1 (en) * | 2022-08-26 | 2024-02-29 | Ethris Gmbh | Stable lipid or lipidoid nanoparticle suspensions |
| EP4327829A1 (en) * | 2022-08-26 | 2024-02-28 | Ethris GmbH | Stabilization of lipid or lipidoid nanoparticle suspensions |
| CN115417778B (zh) * | 2022-11-01 | 2023-06-20 | 北京华芢生物技术有限公司 | 可离子化的阳离子脂c5及由其组成的纳米脂质体颗粒 |
| CN115708818B (zh) * | 2022-11-03 | 2023-07-18 | 荣灿生物医药技术(上海)有限公司 | 一种用于雾化吸入脂质纳米粒的通用型处方 |
| CN115433099B (zh) * | 2022-11-03 | 2023-06-16 | 北京华芢生物技术有限公司 | 可离子化的阳离子脂c6及由其组成的纳米脂质体颗粒 |
| CN120752027A (zh) * | 2023-03-24 | 2025-10-03 | 星锐医药(苏州)有限公司 | 编码治疗性多肽的核酸及包含所述核酸的脂质纳米颗粒组合物 |
| CN121712488A (zh) * | 2023-08-14 | 2026-03-20 | 埃泽瑞斯公司 | 非全身性mRNA施用 |
| CN121729225A (zh) * | 2023-08-25 | 2026-03-24 | 埃泽瑞斯公司 | 具有增强药物应用的特定表面活性剂性质的稳定脂质和类脂质纳米颗粒制剂 |
| WO2025088192A1 (en) | 2023-10-27 | 2025-05-01 | Xl-Protein Gmbh | Methods for the coupling of di(alkyl)amines to polypeptides |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6017700A (en) | 1995-08-04 | 2000-01-25 | Bayer Corporation | Cationic oligonucleotides, and related methods of synthesis and use |
| CA2294334A1 (en) * | 1997-06-13 | 1998-12-17 | Adi Eisenberg | Compositions for delivery of biological agents and methods for the preparation thereof |
| DE19834683A1 (de) | 1997-08-13 | 1999-04-01 | Biontex Lab Gmbh | Neue Lipopolyamine, deren Darstellung und Anwendung |
| DE10160151A1 (de) | 2001-01-09 | 2003-06-26 | Ribopharma Ag | Verfahren zur Hemmung der Expression eines vorgegebenen Zielgens |
| EP1519714B1 (en) | 2002-06-28 | 2010-10-20 | Protiva Biotherapeutics Inc. | Method and apparatus for producing liposomes |
| WO2006138380A2 (en) | 2005-06-15 | 2006-12-28 | Massachusetts Institute Of Technology | Amine-containing lipids and uses thereof |
| NZ569138A (en) | 2005-12-15 | 2012-06-29 | Centre Nat Rech Scient | Cationic oligonucleotides automated methods for preparing same and their uses |
| US7897737B2 (en) | 2006-12-05 | 2011-03-01 | Lasergen, Inc. | 3′-OH unblocked, nucleotides and nucleosides, base modified with photocleavable, terminating groups and methods for their use in DNA sequencing |
| CA2721183C (en) | 2008-04-11 | 2019-07-16 | Alnylam Pharmaceuticals, Inc. | Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components |
| CA2721333C (en) | 2008-04-15 | 2020-12-01 | Protiva Biotherapeutics, Inc. | Novel lipid formulations for nucleic acid delivery |
| EP3269395A1 (en) | 2008-11-07 | 2018-01-17 | Massachusetts Institute Of Technology | Aminoalcohol lipidoids and uses thereof |
| KR101766408B1 (ko) | 2009-06-10 | 2017-08-10 | 알닐람 파마슈티칼스 인코포레이티드 | 향상된 지질 조성물 |
| US9018187B2 (en) | 2009-07-01 | 2015-04-28 | Protiva Biotherapeutics, Inc. | Cationic lipids and methods for the delivery of therapeutic agents |
| CA2769670C (en) | 2009-07-31 | 2018-10-02 | Ethris Gmbh | Rna with a combination of unmodified and modified nucleotides for protein expression |
| US8648017B2 (en) * | 2009-11-04 | 2014-02-11 | Diamir, Llc | Methods of using small RNA from bodily fluids for diagnosis and monitoring of neurodegenerative diseases |
| US9006417B2 (en) | 2010-06-30 | 2015-04-14 | Protiva Biotherapeutics, Inc. | Non-liposomal systems for nucleic acid delivery |
| DE19216461T1 (de) | 2011-10-03 | 2021-10-07 | Modernatx, Inc. | Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon |
| EP2817287B1 (en) | 2012-02-24 | 2018-10-03 | Arbutus Biopharma Corporation | Trialkyl cationic lipids and methods of use thereof |
| WO2014028487A1 (en) | 2012-08-13 | 2014-02-20 | Massachusetts Institute Of Technology | Amine-containing lipidoids and uses thereof |
| US12064484B2 (en) | 2013-06-28 | 2024-08-20 | Ethris Gmbh | Compositions for introducing RNA into cells |
| JP2017500865A (ja) | 2013-12-19 | 2017-01-12 | ノバルティス アーゲー | レプチンｍＲＮＡの組成物および製剤 |
| EP3034539A1 (en) | 2014-12-19 | 2016-06-22 | Ethris GmbH | Compositions for introducing nucleic acid into cells |
-
2022
- 2022-02-25 IL IL305353A patent/IL305353A/en unknown
- 2022-02-25 EP EP22706337.7A patent/EP4297722A1/en active Pending
- 2022-02-25 MX MX2023009757A patent/MX2023009757A/es unknown
- 2022-02-25 KR KR1020237029355A patent/KR20230152014A/ko active Pending
- 2022-02-25 WO PCT/EP2022/054796 patent/WO2022180213A1/en not_active Ceased
- 2022-02-25 AU AU2022226409A patent/AU2022226409A1/en active Pending
- 2022-02-25 US US18/277,965 patent/US20240156729A1/en active Pending
- 2022-02-25 BR BR112023016903A patent/BR112023016903A2/pt unknown
- 2022-02-25 CN CN202280017480.5A patent/CN116887812A/zh active Pending
- 2022-02-25 CA CA3209032A patent/CA3209032A1/en active Pending
- 2022-02-25 JP JP2023551966A patent/JP2024507394A/ja active Pending
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