JP2024503699A - バリアント株ベースのコロナウイルスワクチン - Google Patents

バリアント株ベースのコロナウイルスワクチン Download PDF

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Publication number
JP2024503699A
JP2024503699A JP2023543035A JP2023543035A JP2024503699A JP 2024503699 A JP2024503699 A JP 2024503699A JP 2023543035 A JP2023543035 A JP 2023543035A JP 2023543035 A JP2023543035 A JP 2023543035A JP 2024503699 A JP2024503699 A JP 2024503699A
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JP
Japan
Prior art keywords
cov
sars
antigen
mrna
spike
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2023543035A
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English (en)
Japanese (ja)
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JP2024503699A5 (enExample
Inventor
アンドレア・カーフィ
ギヨーム・スチュアート－ジョーンズ
ハミルトン・ベネット
カイ・ウー
ダリン・エドワーズ
デイヴィッド・リード
グオ－ユ・チュアン
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ModernaTx Inc
Original Assignee
ModernaTx Inc
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Publication date
Application filed by ModernaTx Inc filed Critical ModernaTx Inc
Publication of JP2024503699A publication Critical patent/JP2024503699A/ja
Publication of JP2024503699A5 publication Critical patent/JP2024503699A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2023543035A 2021-01-15 2022-01-14 バリアント株ベースのコロナウイルスワクチン Pending JP2024503699A (ja)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US202163138228P 2021-01-15 2021-01-15
US63/138,228 2021-01-15
US202163140920P 2021-01-24 2021-01-24
US63/140,920 2021-01-24
US202163161433P 2021-03-15 2021-03-15
US63/161,433 2021-03-15
US202163173979P 2021-04-12 2021-04-12
US63/173,979 2021-04-12
US202163193547P 2021-05-26 2021-05-26
US63/193,547 2021-05-26
US202163222925P 2021-07-16 2021-07-16
US63/222,925 2021-07-16
US202163241963P 2021-09-08 2021-09-08
US63/241,963 2021-09-08
US202163283905P 2021-11-29 2021-11-29
US63/283,905 2021-11-29
US202163284570P 2021-11-30 2021-11-30
US63/284,570 2021-11-30
PCT/US2022/012614 WO2022155530A1 (en) 2021-01-15 2022-01-14 Variant strain-based coronavirus vaccines

Publications (2)

Publication Number Publication Date
JP2024503699A true JP2024503699A (ja) 2024-01-26
JP2024503699A5 JP2024503699A5 (enExample) 2025-04-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023543035A Pending JP2024503699A (ja) 2021-01-15 2022-01-14 バリアント株ベースのコロナウイルスワクチン

Country Status (6)

Country Link
US (2) US20240139309A1 (enExample)
EP (1) EP4277653A1 (enExample)
JP (1) JP2024503699A (enExample)
AU (1) AU2022207495A1 (enExample)
CA (1) CA3208303A1 (enExample)
WO (1) WO2022155530A1 (enExample)

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JP2022521094A (ja) 2019-02-20 2022-04-05 モデルナティエックス インコーポレイテッド 共転写キャッピング用ｒｎａポリメラーゼバリアント
CN113874502A (zh) 2019-03-11 2021-12-31 摩登纳特斯有限公司 补料分批体外转录方法
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Also Published As

Publication number Publication date
CA3208303A1 (en) 2022-07-21
WO2022155530A1 (en) 2022-07-21
US20240139309A1 (en) 2024-05-02
US20250367278A1 (en) 2025-12-04
AU2022207495A1 (en) 2023-08-03
WO2022155530A8 (en) 2022-08-18
EP4277653A1 (en) 2023-11-22

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