JP2024503212A5 - - Google Patents

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Publication number
JP2024503212A5
JP2024503212A5 JP2023536871A JP2023536871A JP2024503212A5 JP 2024503212 A5 JP2024503212 A5 JP 2024503212A5 JP 2023536871 A JP2023536871 A JP 2023536871A JP 2023536871 A JP2023536871 A JP 2023536871A JP 2024503212 A5 JP2024503212 A5 JP 2024503212A5
Authority
JP
Japan
Prior art keywords
igg
polypeptide
modified
feline
constant domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023536871A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024503212A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/064097 external-priority patent/WO2022133252A1/en
Publication of JP2024503212A publication Critical patent/JP2024503212A/ja
Publication of JP2024503212A5 publication Critical patent/JP2024503212A5/ja
Pending legal-status Critical Current

Links

JP2023536871A 2020-12-18 2021-12-17 ネコ科動物抗体の定常領域における変異 Pending JP2024503212A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063127313P 2020-12-18 2020-12-18
US63/127,313 2020-12-18
PCT/US2021/064097 WO2022133252A1 (en) 2020-12-18 2021-12-17 Mutations in feline antibody constant regions

Publications (2)

Publication Number Publication Date
JP2024503212A JP2024503212A (ja) 2024-01-25
JP2024503212A5 true JP2024503212A5 (https=) 2024-12-17

Family

ID=79730576

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023536871A Pending JP2024503212A (ja) 2020-12-18 2021-12-17 ネコ科動物抗体の定常領域における変異

Country Status (15)

Country Link
US (1) US20240400708A1 (https=)
EP (1) EP4263596A1 (https=)
JP (1) JP2024503212A (https=)
KR (1) KR20230121056A (https=)
CN (1) CN116547298A (https=)
AU (1) AU2021400322A1 (https=)
CA (1) CA3202074A1 (https=)
CL (2) CL2023001781A1 (https=)
CO (1) CO2023007829A2 (https=)
EC (1) ECSP23044286A (https=)
IL (1) IL303732A (https=)
MX (1) MX2023006898A (https=)
PE (1) PE20231640A1 (https=)
TW (1) TW202233687A (https=)
WO (1) WO2022133252A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230038522A (ko) 2020-07-10 2023-03-20 인베티엑스 인코포레이티드 고양이에서 치료제의 반감기를 증가시키기 위한 조성물 및 사용 방법
WO2022072446A1 (en) 2020-09-29 2022-04-07 Zoetis Services Llc Feline antibody variants
JP2025529206A (ja) * 2022-09-02 2025-09-04 ゾエティス・サービシーズ・エルエルシー 豚抗体変異体
WO2024145280A2 (en) * 2022-12-27 2024-07-04 Invetx, Inc. Polypeptides with altered binding to neonatal fc receptor (fcrn) and methods of use
AU2024210302A1 (en) * 2023-01-20 2025-09-04 Invetx, Inc. Bispecific binding agents for use in companion animals

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6284471B1 (en) 1991-03-18 2001-09-04 New York University Medical Center Anti-TNFa antibodies and assays employing anti-TNFa antibodies
US5698762A (en) 1994-12-09 1997-12-16 Dauerman; Leonard Microwave-assisted pyrolysis of waste polyaromatic hydrocarbons
US20030031671A1 (en) 2001-08-01 2003-02-13 Sydney Welt Methods of treating colon cancer utilizing tumor-specific antibodies
EP1553975B8 (en) * 2002-09-27 2023-04-12 Xencor, Inc. Optimized fc variants and methods for their generation
WO2005037867A1 (en) * 2003-10-15 2005-04-28 Pdl Biopharma, Inc. ALTERATION OF Fc-FUSION PROTEIN SERUM HALF-LIVES BY MUTAGENESIS OF POSITIONS 250, 314 AND/OR 428 OF THE HEAVY CHAIN CONSTANT REGION OF IG
AU2005285347A1 (en) 2004-08-19 2006-03-23 Genentech, Inc. Polypeptide variants with altered effector function
US8546543B2 (en) 2004-11-12 2013-10-01 Xencor, Inc. Fc variants that extend antibody half-life
AU2005304624B2 (en) 2004-11-12 2010-10-07 Xencor, Inc. Fc variants with altered binding to FcRn
US8367805B2 (en) 2004-11-12 2013-02-05 Xencor, Inc. Fc variants with altered binding to FcRn
US20110123440A1 (en) * 2005-03-29 2011-05-26 Genevieve Hansen Altered Antibody FC Regions and Uses Thereof
US20110081347A1 (en) * 2008-06-04 2011-04-07 Macrogenics, Inc. Antibodies with Altered Binding to FcRn and Methods of Using Same
US8790651B2 (en) * 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
US20210388053A1 (en) * 2018-10-18 2021-12-16 Kindred Biosciences, Inc. Fc Variants with Altered Binding to Neonatal Fc Receptor (FCRN) for Veterinary Use
JP7536294B2 (ja) * 2018-12-05 2024-08-20 株式会社バイカ・セラピュティクス 抗体のFc領域改変体
KR20230038522A (ko) * 2020-07-10 2023-03-20 인베티엑스 인코포레이티드 고양이에서 치료제의 반감기를 증가시키기 위한 조성물 및 사용 방법

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