JP2024502174A5 - - Google Patents
Info
- Publication number
- JP2024502174A5 JP2024502174A5 JP2023541657A JP2023541657A JP2024502174A5 JP 2024502174 A5 JP2024502174 A5 JP 2024502174A5 JP 2023541657 A JP2023541657 A JP 2023541657A JP 2023541657 A JP2023541657 A JP 2023541657A JP 2024502174 A5 JP2024502174 A5 JP 2024502174A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- groups
- alkylene
- haloalkyl
- heterocycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163134739P | 2021-01-07 | 2021-01-07 | |
| US63/134,739 | 2021-01-07 | ||
| PCT/CA2022/050014 WO2022147620A1 (en) | 2021-01-07 | 2022-01-07 | Thienyl and cycloalkyl aminopyrimidine compounds as inhibitors of nuak kinases, compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024502174A JP2024502174A (ja) | 2024-01-17 |
| JP2024502174A5 true JP2024502174A5 (https=) | 2024-12-10 |
Family
ID=82356983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023541657A Pending JP2024502174A (ja) | 2021-01-07 | 2022-01-07 | Ｎｕａｋキナーゼの阻害剤としてのチエニル及びシクロアルキルアミノピリミジン化合物、その組成物及び使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240025887A1 (https=) |
| EP (1) | EP4274829A4 (https=) |
| JP (1) | JP2024502174A (https=) |
| CN (1) | CN116981664A (https=) |
| AU (1) | AU2022205713A1 (https=) |
| CA (1) | CA3204383A1 (https=) |
| WO (1) | WO2022147620A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116903591B (zh) * | 2023-07-13 | 2025-08-26 | 特科罗生物科技(成都)有限公司 | 一种嘧啶胺类nuak抑制剂及其制备方法和用途 |
| CN116903592B (zh) * | 2023-07-13 | 2025-08-01 | 特科罗生物科技(成都)有限公司 | 一种嘧啶胺类nuak抑制剂及其制备方法和用途 |
| CN116947764B9 (zh) * | 2023-07-13 | 2025-07-25 | 特科罗生物科技(成都)有限公司 | 一种嘧啶胺类nuak抑制剂及其制备方法和用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7754714B2 (en) * | 2004-05-18 | 2010-07-13 | Rigel Pharmaceuticals, Inc. | Cycloalkyl substituted pyrimidinediamine compounds and their uses |
| EP1883302A4 (en) * | 2005-05-03 | 2009-05-20 | Rigel Pharmaceuticals Inc | JAK KINASE HEMMER AND ITS USE |
| CA2634646C (en) * | 2005-12-21 | 2012-04-10 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| CA2648170A1 (en) * | 2006-04-10 | 2007-10-18 | Boehringer Ingelheim International Gmbh | 2, 4-diaminopyrimidine derivatives and their use for the treatment of cancer |
| ES2555803T3 (es) * | 2006-10-23 | 2016-01-08 | Cephalon, Inc. | Fusión de derivados bicíclicos 2,4-diaminopirimidina como utilizar inhibidores ALK y c-Met |
| WO2008077885A2 (en) * | 2006-12-22 | 2008-07-03 | Boehringer Ingelheim International Gmbh | 2- [(phenylamino) -pyrimidin-4ylamin0] -cyclopentane carboxamide derivatives and related compounds as inhibitors of kinases of the cell cycle for the treatment of cancer |
| EA017252B1 (ru) * | 2007-08-28 | 2012-11-30 | Айрм Ллк | Производные 2-бифениламино-4-аминопиримидина в качестве ингибиторов киназ |
| MX353308B (es) * | 2008-05-21 | 2018-01-08 | Ariad Pharma Inc | Derivados fosforosos como inhibidores de cinasa. |
| WO2012051587A1 (en) * | 2010-10-14 | 2012-04-19 | Ariad Pharmaceuticals, Inc. | Methods for inhibiting cell proliferation in egfr-driven cancers |
| CN110724137B (zh) * | 2019-11-13 | 2021-03-30 | 广东工业大学 | 一种噻吩类衍生物及其制备方法与应用 |
-
2022
- 2022-01-07 US US18/271,089 patent/US20240025887A1/en active Pending
- 2022-01-07 AU AU2022205713A patent/AU2022205713A1/en not_active Abandoned
- 2022-01-07 CN CN202280019540.7A patent/CN116981664A/zh active Pending
- 2022-01-07 JP JP2023541657A patent/JP2024502174A/ja active Pending
- 2022-01-07 EP EP22736479.1A patent/EP4274829A4/en not_active Withdrawn
- 2022-01-07 CA CA3204383A patent/CA3204383A1/en active Pending
- 2022-01-07 WO PCT/CA2022/050014 patent/WO2022147620A1/en not_active Ceased
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