JP2024501453A5 - - Google Patents

Info

Publication number
JP2024501453A5
JP2024501453A5 JP2023535317A JP2023535317A JP2024501453A5 JP 2024501453 A5 JP2024501453 A5 JP 2024501453A5 JP 2023535317 A JP2023535317 A JP 2023535317A JP 2023535317 A JP2023535317 A JP 2023535317A JP 2024501453 A5 JP2024501453 A5 JP 2024501453A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
cdr
alkyldiyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2023535317A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024501453A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/062797 external-priority patent/WO2022125891A2/en
Publication of JP2024501453A publication Critical patent/JP2024501453A/ja
Publication of JP2024501453A5 publication Critical patent/JP2024501453A5/ja
Withdrawn legal-status Critical Current

Links

JP2023535317A 2020-12-11 2021-12-10 抗ceaイムノコンジュゲート、及びそれらの使用 Withdrawn JP2024501453A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063124353P 2020-12-11 2020-12-11
US63/124,353 2020-12-11
PCT/US2021/062797 WO2022125891A2 (en) 2020-12-11 2021-12-10 Anti-cea immunoconjugates, and uses thereof

Publications (2)

Publication Number Publication Date
JP2024501453A JP2024501453A (ja) 2024-01-12
JP2024501453A5 true JP2024501453A5 (enExample) 2024-12-10

Family

ID=79425667

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023535317A Withdrawn JP2024501453A (ja) 2020-12-11 2021-12-10 抗ceaイムノコンジュゲート、及びそれらの使用

Country Status (6)

Country Link
US (1) US20240238430A1 (enExample)
EP (1) EP4259210A2 (enExample)
JP (1) JP2024501453A (enExample)
CN (1) CN116635084A (enExample)
CA (1) CA3200051A1 (enExample)
WO (1) WO2022125891A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3200056A1 (en) 2020-12-11 2022-06-16 Shelley Erin ACKERMAN Anti-her2 immunoconjugates, and uses thereof
WO2023154318A1 (en) * 2022-02-09 2023-08-17 Bolt Biotherapeutics, Inc. Anti-tr0p2, aminobenzazepine immunoconjugates, and uses thereof
WO2024173387A1 (en) 2023-02-14 2024-08-22 Bolt Biotherapeutics, Inc. Aza-benzazepine immunoconjugates, and uses thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
US5874540A (en) 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
AU5345901A (en) 2000-04-13 2001-10-30 Univ Rockefeller Enhancement of antibody-mediated immune responses
US7232888B2 (en) 2002-07-01 2007-06-19 Massachusetts Institute Of Technology Antibodies against tumor surface antigens
WO2005086875A2 (en) 2004-03-11 2005-09-22 City Of Hope A humanized anti-cea t84.66 antibody and uses thereof
TR201808537T4 (tr) 2004-09-23 2018-07-23 Genentech Inc Sistein değiştirilmiş antikorlar ve konjugatlar.
US20070014795A1 (en) 2004-12-30 2007-01-18 Dhodapkar Madhav V Compositions and methods for enhanced dendritic cell maturation and function
AU2006312148B2 (en) 2005-11-07 2012-04-12 The Rockefeller University Reagents, methods and systems for selecting a cytotoxic antibody or variant thereof
NZ569204A (en) 2005-12-21 2012-03-30 Micromet Ag Pharmaceutical compositions with resistance to soluble CEA - comprising antibodies that bind to CD3 and CEA
PE20090245A1 (es) 2007-05-08 2009-03-17 Genentech Inc Anticuerpos anti-muc16 disenados con cisteina y conjugados de anticuerpos y farmacos
BRPI0818780A2 (pt) 2007-10-19 2015-04-22 Genentech Inc Anticorpo anti-tenb2 planejados por cisteína e conjugados de medicamento com anticorpos
EP2640727B1 (en) 2010-11-17 2015-05-13 Genentech, Inc. Alaninyl maytansinol antibody conjugates
KR101981342B1 (ko) 2011-03-02 2019-05-22 로슈 글리카트 아게 Cea 항체
PT3199552T (pt) 2012-11-20 2020-03-25 Sanofi Sa Anticorpos anti-ceacam5 e suas utilizações
HRP20210977T1 (hr) 2014-02-10 2021-09-17 Merck Patent Gmbh Ciljano inhibiranje tgf beta
JP6805142B2 (ja) 2014-11-21 2020-12-23 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Cd73に対する抗体およびその使用
EP3849971A2 (en) * 2018-09-12 2021-07-21 Silverback Therapeutics, Inc. Substituted benzazepine compounds, conjugates, and uses thereof
EP3983080A1 (en) * 2019-06-13 2022-04-20 Bolt Biotherapeutics, Inc. Macromolecule-supported aminobenzazepine compounds
JP2022537158A (ja) * 2019-06-13 2022-08-24 ボルト バイオセラピューティクス、インコーポレーテッド アミノベンズアゼピン化合物、イムノコンジュゲート、及びそれらの使用
CA3176626A1 (en) * 2020-05-08 2021-11-11 David Dornan Elastase-substrate, peptide linker immunoconjugates, and uses thereof

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