JP2024501453A5 - - Google Patents
Info
- Publication number
- JP2024501453A5 JP2024501453A5 JP2023535317A JP2023535317A JP2024501453A5 JP 2024501453 A5 JP2024501453 A5 JP 2024501453A5 JP 2023535317 A JP2023535317 A JP 2023535317A JP 2023535317 A JP2023535317 A JP 2023535317A JP 2024501453 A5 JP2024501453 A5 JP 2024501453A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- cdr
- alkyldiyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063124353P | 2020-12-11 | 2020-12-11 | |
| US63/124,353 | 2020-12-11 | ||
| PCT/US2021/062797 WO2022125891A2 (en) | 2020-12-11 | 2021-12-10 | Anti-cea immunoconjugates, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024501453A JP2024501453A (ja) | 2024-01-12 |
| JP2024501453A5 true JP2024501453A5 (enExample) | 2024-12-10 |
Family
ID=79425667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023535317A Withdrawn JP2024501453A (ja) | 2020-12-11 | 2021-12-10 | 抗ｃｅａイムノコンジュゲート、及びそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240238430A1 (enExample) |
| EP (1) | EP4259210A2 (enExample) |
| JP (1) | JP2024501453A (enExample) |
| CN (1) | CN116635084A (enExample) |
| CA (1) | CA3200051A1 (enExample) |
| WO (1) | WO2022125891A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023154318A1 (en) * | 2022-02-09 | 2023-08-17 | Bolt Biotherapeutics, Inc. | Anti-tr0p2, aminobenzazepine immunoconjugates, and uses thereof |
| WO2024173384A1 (en) | 2023-02-14 | 2024-08-22 | Bolt Biotherapeutics, Inc. | Aza-benzazepine immunoconjugates, and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5874540A (en) | 1994-10-05 | 1999-02-23 | Immunomedics, Inc. | CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies |
| JP2003531149A (ja) | 2000-04-13 | 2003-10-21 | ザ・ロツクフエラー・ユニバーシテイ | 抗体由来の免疫応答の増強 |
| US7232888B2 (en) | 2002-07-01 | 2007-06-19 | Massachusetts Institute Of Technology | Antibodies against tumor surface antigens |
| US7273608B2 (en) | 2004-03-11 | 2007-09-25 | City Of Hope | Humanized anti-CEA T84.66 antibody and uses thereof |
| DK1791565T3 (en) | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
| WO2006073921A2 (en) | 2004-12-30 | 2006-07-13 | The Rockefeller University | Compositions and methods for enhanced dendritic cell maturation and function |
| US20080286819A1 (en) | 2005-11-07 | 2008-11-20 | Ravetch Jeffrey V | Reagents, Methods and Systems for Selecting a Cytotoxic Antibody or Variant Thereof |
| JP5399712B2 (ja) | 2005-12-21 | 2014-01-29 | アムゲン リサーチ （ミュンヘン） ゲーエムベーハー | 可溶性ｃｅａに対する抵抗性を有する医薬組成物 |
| CL2008001334A1 (es) | 2007-05-08 | 2008-09-22 | Genentech Inc | Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer. |
| NZ584514A (en) | 2007-10-19 | 2012-07-27 | Genentech Inc | Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates |
| US20120121615A1 (en) | 2010-11-17 | 2012-05-17 | Flygare John A | Alaninyl maytansinol antibody conjugates |
| PE20141017A1 (es) | 2011-03-02 | 2014-08-25 | Roche Glycart Ag | Anticuerpos del cea |
| DK3199552T3 (da) | 2012-11-20 | 2020-03-30 | Sanofi Sa | Anti-ceacam5-antistoffer og anvendelser heraf |
| BR112016014952A2 (pt) | 2014-02-10 | 2017-09-19 | Merck Patent Gmbh | Inibição direcionada de tgfbeta |
| AU2015349878A1 (en) | 2014-11-21 | 2017-05-25 | Bristol-Myers Squibb Company | Antibodies against CD73 and uses thereof |
| AU2019337654A1 (en) * | 2018-09-12 | 2021-04-08 | Silverback Therapeutics, Inc. | Substituted benzazepine compounds, conjugates, and uses thereof |
| JP7558205B2 (ja) * | 2019-06-13 | 2024-09-30 | ボルト バイオセラピューティクス、インコーポレーテッド | 高分子支持アミノベンズアピン化合物 |
| US20200390899A1 (en) * | 2019-06-13 | 2020-12-17 | Bolt Biotherapeutics, Inc. | Aminobenzazepine compounds, immunoconjugates, and uses thereof |
| US20230293716A1 (en) * | 2020-05-08 | 2023-09-21 | Bolt Biotherapeutics, Inc. | Elastase-substrate, peptide linker immunoconjugates, and uses thereof |
-
2021
- 2021-12-10 CN CN202180083382.7A patent/CN116635084A/zh active Pending
- 2021-12-10 US US18/038,904 patent/US20240238430A1/en active Pending
- 2021-12-10 JP JP2023535317A patent/JP2024501453A/ja not_active Withdrawn
- 2021-12-10 EP EP21841071.0A patent/EP4259210A2/en not_active Withdrawn
- 2021-12-10 CA CA3200051A patent/CA3200051A1/en active Pending
- 2021-12-10 WO PCT/US2021/062797 patent/WO2022125891A2/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022553702A5 (enExample) | ||
| JP2022537158A5 (enExample) | ||
| JP2023553421A5 (ja) | 抗ｃｅａ免疫複合体、及びその使用 | |
| JP2023524271A5 (enExample) | ||
| JP2024523453A5 (enExample) | ||
| JP2022549510A5 (enExample) | ||
| WO2023208216A9 (en) | Antibody-drug conjugates and preparation methods and use thereof | |
| JP2024521629A (ja) | 抗体薬物コンジュゲート、及びその調製方法及びその使用 | |
| JP2023552792A5 (enExample) | ||
| JP2022546110A5 (enExample) | ||
| JP2024545233A5 (enExample) | ||
| JP2024501453A5 (enExample) | ||
| JP2022550851A5 (enExample) | ||
| JP2023527962A5 (enExample) | ||
| JP2022554094A5 (enExample) | ||
| JP2024509099A5 (enExample) | ||
| JP2024533356A5 (enExample) | ||
| JP2025533758A (ja) | 抗体－薬物複合体並びにその調製方法及び使用 | |
| JP2023552790A5 (enExample) | ||
| JP2023552791A5 (enExample) | ||
| JP2025541673A (ja) | ヘテロ環化合物並びにその製造方法及び用途 | |
| JP2025539841A5 (enExample) | ||
| WO2024227439A1 (zh) | 具有靶向作用的偶联物及其制备方法和用途 | |
| JP2023537940A5 (enExample) | ||
| CN120957761A (zh) | 具有靶向作用的偶联物及其制备方法和用途 |