JP2022546110A5 - - Google Patents

Info

Publication number
JP2022546110A5
JP2022546110A5 JP2022513850A JP2022513850A JP2022546110A5 JP 2022546110 A5 JP2022546110 A5 JP 2022546110A5 JP 2022513850 A JP2022513850 A JP 2022513850A JP 2022513850 A JP2022513850 A JP 2022513850A JP 2022546110 A5 JP2022546110 A5 JP 2022546110A5
Authority
JP
Japan
Prior art keywords
alkyldiyl
heterocyclyldiyl
peg
group
aminoquinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022513850A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022546110A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/049041 external-priority patent/WO2021046112A1/en
Publication of JP2022546110A publication Critical patent/JP2022546110A/ja
Publication of JP2022546110A5 publication Critical patent/JP2022546110A5/ja
Pending legal-status Critical Current

Links

JP2022513850A 2019-09-03 2020-09-02 アミノキノリン化合物、免疫複合体、及びそれらの使用 Pending JP2022546110A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962895379P 2019-09-03 2019-09-03
US62/895,379 2019-09-03
PCT/US2020/049041 WO2021046112A1 (en) 2019-09-03 2020-09-02 Aminoquinoline compounds, immunoconjugates, and uses thereof

Publications (2)

Publication Number Publication Date
JP2022546110A JP2022546110A (ja) 2022-11-02
JP2022546110A5 true JP2022546110A5 (enExample) 2023-08-30

Family

ID=72561946

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022513850A Pending JP2022546110A (ja) 2019-09-03 2020-09-02 アミノキノリン化合物、免疫複合体、及びそれらの使用

Country Status (6)

Country Link
US (1) US20220313835A1 (enExample)
EP (1) EP4025254A1 (enExample)
JP (1) JP2022546110A (enExample)
CN (1) CN114630684A (enExample)
CA (1) CA3148694A1 (enExample)
WO (1) WO2021046112A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109843327B (zh) 2016-07-07 2022-05-13 小利兰·斯坦福大学托管委员会 抗体佐剂缀合物
WO2020190725A1 (en) 2019-03-15 2020-09-24 Bolt Biotherapeutics, Inc. Immunoconjugates targeting her2
US20230293716A1 (en) * 2020-05-08 2023-09-21 Bolt Biotherapeutics, Inc. Elastase-substrate, peptide linker immunoconjugates, and uses thereof
JP2024539993A (ja) 2021-10-29 2024-10-31 ボルト バイオセラピューティクス、インコーポレーテッド システイン変異抗体を含むtlrアゴニスト免疫複合体、及びその使用
TW202440164A (zh) 2022-12-13 2024-10-16 美商克林提克斯醫藥股份有限公司 生長抑素亞型-2受體(sst2r)靶向治療劑及其用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US723288A (en) 1901-10-26 1903-03-24 Harry South Lewis Cipher-key for cryptographic codes.
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
JP3040121B2 (ja) 1988-01-12 2000-05-08 ジェネンテク,インコーポレイテッド 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
US5874540A (en) 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
NZ507557A (en) 1998-05-06 2003-10-31 Genentech Inc Protein purification by ion exchange chromatography
JP2003531149A (ja) 2000-04-13 2003-10-21 ザ・ロツクフエラー・ユニバーシテイ 抗体由来の免疫応答の増強
MXPA05013922A (es) * 2003-06-20 2006-02-24 Coley Pharm Group Inc Antagonistas de receptor tipo toll de molecula pequena.
US7273608B2 (en) 2004-03-11 2007-09-25 City Of Hope Humanized anti-CEA T84.66 antibody and uses thereof
DK1791565T3 (en) 2004-09-23 2016-08-01 Genentech Inc Cysteingensplejsede antibodies and conjugates
WO2006073921A2 (en) 2004-12-30 2006-07-13 The Rockefeller University Compositions and methods for enhanced dendritic cell maturation and function
US20080286819A1 (en) 2005-11-07 2008-11-20 Ravetch Jeffrey V Reagents, Methods and Systems for Selecting a Cytotoxic Antibody or Variant Thereof
JP5399712B2 (ja) 2005-12-21 2014-01-29 アムゲン リサーチ (ミュンヘン) ゲーエムベーハー 可溶性ceaに対する抵抗性を有する医薬組成物
CL2008001334A1 (es) 2007-05-08 2008-09-22 Genentech Inc Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer.
NZ584514A (en) 2007-10-19 2012-07-27 Genentech Inc Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates
US20120121615A1 (en) 2010-11-17 2012-05-17 Flygare John A Alaninyl maytansinol antibody conjugates
PE20141017A1 (es) 2011-03-02 2014-08-25 Roche Glycart Ag Anticuerpos del cea
DK3199552T3 (da) 2012-11-20 2020-03-30 Sanofi Sa Anti-ceacam5-antistoffer og anvendelser heraf
BR112016014952A2 (pt) 2014-02-10 2017-09-19 Merck Patent Gmbh Inibição direcionada de tgfbeta
AU2015349878A1 (en) 2014-11-21 2017-05-25 Bristol-Myers Squibb Company Antibodies against CD73 and uses thereof
DE212016000029U1 (de) * 2015-12-07 2017-07-30 Opi Vi - Ip Holdco Llc Zusammensetzungen von Antikörperkonstrukt-Agonist-Konjugaten
US20190336615A1 (en) * 2017-01-27 2019-11-07 Silverback Therapeutics, Inc. Tumor targeting conjugates and methods of use thereof
WO2019084060A1 (en) * 2017-10-24 2019-05-02 Silverback Therapeutics, Inc. CONJUGATES AND METHODS OF USE FOR THE SELECTIVE DELIVERY OF IMMUNOMODULATORY AGENTS

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