JP2024500405A5 - - Google Patents

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Publication number
JP2024500405A5
JP2024500405A5 JP2023536830A JP2023536830A JP2024500405A5 JP 2024500405 A5 JP2024500405 A5 JP 2024500405A5 JP 2023536830 A JP2023536830 A JP 2023536830A JP 2023536830 A JP2023536830 A JP 2023536830A JP 2024500405 A5 JP2024500405 A5 JP 2024500405A5
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JP
Japan
Prior art keywords
seq
sequence
region
binding molecule
immunoglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023536830A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024500405A (ja
Filing date
Publication date
Priority claimed from GBGB2020154.7A external-priority patent/GB202020154D0/en
Application filed filed Critical
Publication of JP2024500405A publication Critical patent/JP2024500405A/ja
Publication of JP2024500405A5 publication Critical patent/JP2024500405A5/ja
Pending legal-status Critical Current

Links

JP2023536830A 2020-12-18 2021-12-17 Ror1特異的バリアント抗原結合分子 Pending JP2024500405A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2020154.7A GB202020154D0 (en) 2020-12-18 2020-12-18 ROR1-specific variant antigen binding molecules
GB2020154.7 2020-12-18
PCT/EP2021/086667 WO2022129622A1 (en) 2020-12-18 2021-12-17 Ror1-specific variant antigen binding molecules

Publications (2)

Publication Number Publication Date
JP2024500405A JP2024500405A (ja) 2024-01-09
JP2024500405A5 true JP2024500405A5 (https=) 2024-12-24

Family

ID=74221003

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023536830A Pending JP2024500405A (ja) 2020-12-18 2021-12-17 Ror1特異的バリアント抗原結合分子

Country Status (11)

Country Link
US (1) US20250269051A1 (https=)
EP (1) EP4262987A1 (https=)
JP (1) JP2024500405A (https=)
KR (1) KR20230121130A (https=)
CN (1) CN116888155A (https=)
AU (1) AU2021402087A1 (https=)
CA (1) CA3201781A1 (https=)
GB (1) GB202020154D0 (https=)
IL (1) IL303735A (https=)
MX (1) MX2023007282A (https=)
WO (1) WO2022129622A1 (https=)

Families Citing this family (10)

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Publication number Priority date Publication date Assignee Title
US12144827B2 (en) 2021-02-25 2024-11-19 Lyell Immunopharma, Inc. ROR1 targeting chimeric antigen receptor
IL312204A (en) 2021-10-28 2024-06-01 Lyell Immunopharma Inc Methods for culturing cells expressing ror1-binding protein
CN119789865A (zh) * 2022-06-22 2025-04-08 阿尔麦克探索有限公司 Ror1/egfr双特异性抗原结合分子
WO2024008112A1 (en) * 2022-07-06 2024-01-11 Nona Biosciences (Suzhou) Co., Ltd. Anti-ror1 antibodies
KR20240016216A (ko) * 2022-07-26 2024-02-06 (주)에임드바이오 항-ror1 항체 및 이의 용도
WO2024064952A1 (en) 2022-09-23 2024-03-28 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells overexpressing c-jun
WO2024064958A1 (en) 2022-09-23 2024-03-28 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells
WO2024077174A1 (en) 2022-10-05 2024-04-11 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells
WO2025217398A1 (en) 2024-04-10 2025-10-16 Lyell Immunopharma, Inc. Methods for culturing cells with improved culture medium
CN119431574B (zh) * 2025-01-13 2025-06-27 青岛科技大学 靶向多物种血清白蛋白的鲨鱼单域抗体及其制备方法和应用

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PL1651664T3 (pl) 2003-08-05 2009-09-30 Almac Sciences Scotland Ltd Sposób ligacji
EP2240495B1 (en) 2008-02-01 2015-07-15 Genentech, Inc. Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
CA2759733C (en) 2009-04-23 2019-09-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-human ror1 antibodies
WO2011054007A1 (en) 2009-11-02 2011-05-05 Oxford Biotherapeutics Ltd. Ror1 as therapeutic and diagnostic target
US9150647B2 (en) 2009-12-18 2015-10-06 Kancera Ab Biological inhibitors of ROR1 capable of inducing cell death
ES2657970T3 (es) 2010-12-01 2018-03-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anticuerpos contra ROR1 de conejo/ser humano quiméricos
KR101897307B1 (ko) 2010-12-02 2018-09-10 네르비아노 메디칼 사이언시스 에스.알.엘. 모르폴리닐 안트라사이클린 유도체의 제조 방법
EP4151658A1 (en) 2012-05-07 2023-03-22 Elasmogen Limited Single domain binding molecule
WO2014028776A1 (en) 2012-08-15 2014-02-20 Zyngenia, Inc. Monovalent and multivalent multispecific complexes and uses thereof
ES2702315T3 (es) 2012-08-24 2019-02-28 Univ California Anticuerpos y vacunas para su uso en tratar cánceres ROR1 e inhibir metástasis
JP6616284B2 (ja) * 2013-04-23 2019-12-04 ザ ユニバーシティ コート オブ ザ ユニバーシティ オブ アバディーン 特異的結合分子の人工ライブラリー
RU2689717C2 (ru) * 2014-01-08 2019-05-28 Шанхай Хэнжуй Фармасьютикал Ко., Лтд. Гетеродимерный белок il-15 и его применения
EP3160995A2 (en) * 2014-06-26 2017-05-03 Ossianix Inc. Semi-synthetic nurse shark vnar libraries for making and using selective binding compounds
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UA125718C2 (uk) 2016-01-20 2022-05-25 Зе Скріппс Ресеарч Інстітьют Композиції антитіл до ror1 і пов'язані з ними способи
TW201734049A (zh) 2016-01-22 2017-10-01 健生生物科技公司 抗-ror1抗體、ror1 x cd3雙特異性抗體及使用其之方法
GB201721802D0 (en) * 2017-12-22 2018-02-07 Almac Discovery Ltd Ror1-specific antigen binding molecules
CN112812743A (zh) 2019-11-15 2021-05-18 圣戈班磨料磨具有限公司 磨料制品及其形成方法

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