JP2024500136A5 - - Google Patents
Info
- Publication number
- JP2024500136A5 JP2024500136A5 JP2023537316A JP2023537316A JP2024500136A5 JP 2024500136 A5 JP2024500136 A5 JP 2024500136A5 JP 2023537316 A JP2023537316 A JP 2023537316A JP 2023537316 A JP2023537316 A JP 2023537316A JP 2024500136 A5 JP2024500136 A5 JP 2024500136A5
- Authority
- JP
- Japan
- Prior art keywords
- oxopyrrolidine
- butan
- dioxo
- cyclopropylamino
- dimethylpentanamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2020190.1 | 2020-12-18 | ||
| GBGB2020190.1A GB202020190D0 (en) | 2020-12-18 | 2020-12-18 | Sars-Cov-2 MPRO inhibitor compounds |
| GBGB2107385.3A GB202107385D0 (en) | 2021-05-24 | 2021-05-24 | Sars-cov-2 mpro inhibitor compounds |
| GB2107385.3 | 2021-05-24 | ||
| PCT/GB2021/053374 WO2022129953A1 (en) | 2020-12-18 | 2021-12-20 | Sars-cov-2 mpro inhibitor compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024500136A JP2024500136A (ja) | 2024-01-04 |
| JP2024500136A5 true JP2024500136A5 (cg-RX-API-DMAC7.html) | 2024-12-26 |
Family
ID=79282959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023537316A Pending JP2024500136A (ja) | 2020-12-18 | 2021-12-20 | Ｓａｒｓ－ｃｏｖ－２ ｍｐｒｏ阻害薬化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240083845A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4263502B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2024500136A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20230121780A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2021402179A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3204314A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL303757A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2022129953A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4545075A1 (en) * | 2022-06-23 | 2025-04-30 | Goryo Chemical, Inc. | Calpain inhibitor |
| CN115073347B (zh) * | 2022-07-14 | 2024-07-30 | 浙江江北药业有限公司 | 一种内酰胺环类医药中间体的制备方法 |
| WO2024102455A1 (en) * | 2022-11-09 | 2024-05-16 | Emory University | Non-covalent inhibitors of coronavirus main protease |
| CN116535460A (zh) * | 2023-04-28 | 2023-08-04 | 中国人民解放军军事科学院军事医学研究院 | 一类含硫拟肽类化合物及其制备方法和用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763576A (en) * | 1995-10-06 | 1998-06-09 | Georgia Tech Research Corp. | Tetrapeptide α-ketoamides |
| SK6572000A3 (en) * | 1997-11-05 | 2000-10-09 | Novartis Ag | Dipeptide nitriles, process for the preparation thereof, their use as medicaments and pharmaceutical composition comprising them |
| WO2004093860A1 (en) * | 2003-04-21 | 2004-11-04 | Pfizer Inc. | Inhibitors of sars related coronavirus proteinase |
| WO2005113580A1 (en) * | 2004-05-21 | 2005-12-01 | Pfizer Inc. | Anticoronviral compounds and compositions, their pharmaceutical uses and materials for their synthesis |
| CN100363346C (zh) * | 2004-10-22 | 2008-01-23 | 清华大学 | 冠状病毒主蛋白酶的小分子抑制剂、制备方法及其应用 |
| WO2006061714A2 (en) * | 2004-12-09 | 2006-06-15 | Pfizer Inc. | Anticoronaviral compounds and compositions, their pharmaceutical uses and materials for their synthesis |
| CA2850003C (en) * | 2011-09-27 | 2020-01-07 | Kansas State University Research Foundation | Broad-spectrum antivirals against 3c or 3c-like proteases of picornavirus-like supercluster: picornaviruses, caliciviruses and coronaviruses |
| CN103130710B (zh) * | 2011-11-29 | 2015-12-16 | 南开大学 | 抗肠病毒71(ev71)己内酰胺醛类化合物及其制备方法和用途 |
| CN103145608B (zh) * | 2011-12-07 | 2015-09-02 | 南开大学 | 抗肠病毒71(ev71)己内酰胺类化合物及其制备方法和用途 |
| TW201817714A (zh) * | 2016-08-30 | 2018-05-16 | 英商葛蘭素史密斯克藍智慧財產權有限公司 | 抑制3c及3cl蛋白酶之化合物及其使用方法 |
| CN110818691A (zh) * | 2018-08-09 | 2020-02-21 | 中国科学院上海药物研究所 | 酮酰胺类化合物及其制备方法、药物组合物和用途 |
-
2021
- 2021-12-20 US US18/258,065 patent/US20240083845A1/en active Pending
- 2021-12-20 JP JP2023537316A patent/JP2024500136A/ja active Pending
- 2021-12-20 KR KR1020237022567A patent/KR20230121780A/ko active Pending
- 2021-12-20 CA CA3204314A patent/CA3204314A1/en active Pending
- 2021-12-20 AU AU2021402179A patent/AU2021402179A1/en not_active Abandoned
- 2021-12-20 IL IL303757A patent/IL303757A/en unknown
- 2021-12-20 WO PCT/GB2021/053374 patent/WO2022129953A1/en not_active Ceased
- 2021-12-20 EP EP21839626.5A patent/EP4263502B1/en active Active
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