JP2024100972A5 - - Google Patents
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- JP2024100972A5 JP2024100972A5 JP2024084707A JP2024084707A JP2024100972A5 JP 2024100972 A5 JP2024100972 A5 JP 2024100972A5 JP 2024084707 A JP2024084707 A JP 2024084707A JP 2024084707 A JP2024084707 A JP 2024084707A JP 2024100972 A5 JP2024100972 A5 JP 2024100972A5
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- JP
- Japan
- Prior art keywords
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- subject
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- small molecule
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862656823P | 2018-04-12 | 2018-04-12 | |
| US62/656,823 | 2018-04-12 | ||
| JP2021505621A JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
| PCT/US2019/026923 WO2019200056A2 (en) | 2018-04-12 | 2019-04-11 | Viral vectors and packaging cell lines |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505621A Division JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024100972A JP2024100972A (ja) | 2024-07-26 |
| JP2024100972A5 true JP2024100972A5 (https=) | 2025-01-30 |
Family
ID=66287035
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505621A Active JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
| JP2024084707A Pending JP2024100972A (ja) | 2018-04-12 | 2024-05-24 | ウイルスベクター及びパッケージング細胞株 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505621A Active JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US12215337B2 (https=) |
| EP (1) | EP3775231A2 (https=) |
| JP (2) | JP7721436B2 (https=) |
| CN (1) | CN112262214A (https=) |
| AU (2) | AU2019252285B2 (https=) |
| BR (1) | BR112020020887A2 (https=) |
| CA (1) | CA3096458A1 (https=) |
| IL (1) | IL277936A (https=) |
| SG (1) | SG11202009975TA (https=) |
| WO (1) | WO2019200056A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| US12590321B2 (en) | 2016-03-19 | 2026-03-31 | Exuma Biotech Corp. | Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof |
| US11325948B2 (en) | 2016-03-19 | 2022-05-10 | Exuma Biotech Corp. | Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL |
| US11111505B2 (en) | 2016-03-19 | 2021-09-07 | Exuma Biotech, Corp. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| JP7178355B2 (ja) | 2017-02-28 | 2022-11-25 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための組成物および方法 |
| JP7549303B2 (ja) | 2018-01-22 | 2024-09-11 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞の使用方法 |
| CN112105382A (zh) | 2018-02-23 | 2020-12-18 | 恩多塞特公司 | 用于car t细胞疗法的顺序方法 |
| CN112262214A (zh) | 2018-04-12 | 2021-01-22 | 优莫佳生物制药股份有限公司 | 病毒载体及包装细胞系 |
| WO2020106992A1 (en) | 2018-11-21 | 2020-05-28 | Umoja Biopharma, Inc. | Multicistronic vector for surface engineering lentiviral particles |
| US20240122978A1 (en) * | 2019-10-16 | 2024-04-18 | Umoja Biopharma, Inc. | Retroviral vector for univeral receptor therapy |
| US20230348624A1 (en) | 2020-01-30 | 2023-11-02 | Umoja Biopharma, Inc. | Bispecific transduction enhancer |
| US20230201440A1 (en) * | 2020-05-08 | 2023-06-29 | Innovative Cellular Therapeutics Holdings, Ltd. | System and method for gene and/or cellular therapy |
| CA3199588A1 (en) * | 2020-11-20 | 2022-05-27 | Andrew Scharenberg | Vector system for delivery of multiple polynucleotides and uses thereof |
| MX2023008831A (es) | 2021-01-27 | 2023-10-19 | Umoja Biopharma Inc | Lentivirus para generar células que expresan receptores de antígeno quimérico anti-cd19. |
| JP2025517138A (ja) * | 2022-05-06 | 2025-06-03 | ウモジャ バイオファーマ インコーポレイテッド | 表面刺激分子を有するウイルス粒子 |
| WO2024097992A2 (en) * | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Particles displaying adhesion-molecule fusions |
| JP2026500897A (ja) * | 2022-11-04 | 2026-01-09 | ウモジャ バイオファーマ インコーポレイテッド | 融合分子を呈示するレンチウイルス粒子およびその使用 |
| WO2024215987A1 (en) | 2023-04-14 | 2024-10-17 | Sotio Biotech Inc. | IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES |
| EP4694916A1 (en) | 2023-04-14 | 2026-02-18 | SOTIO Biotech Inc. | Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists |
| KR20260005358A (ko) | 2023-04-27 | 2026-01-09 | 밀테니 비오텍 비.브이. & 씨오. 케이지 | 항-cd3 디스플레이를 갖는 슈도타이핑된 레트로바이러스 벡터 입자 |
| WO2024238153A1 (en) * | 2023-05-15 | 2024-11-21 | Umoja Biopharma, Inc. | Lentiviral delivery of anti-cd20 chimeric antigen receptors |
| WO2024238769A2 (en) * | 2023-05-16 | 2024-11-21 | The Regents Of The University Of California | Inhibitory chimeric antigen receptors that reduce car-t cell "on-target, off-tumor" toxicity |
| WO2025078492A1 (en) | 2023-10-13 | 2025-04-17 | Miltenyi Biotec B.V. & Co. KG | Cd3-targeted nipah-pseudotyped lentiviral vector particles |
| WO2025162379A1 (zh) * | 2024-02-01 | 2025-08-07 | 深圳市济因生物科技有限公司 | 一种多肽及包含所述多肽基因的病毒载体 |
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| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5739018A (en) | 1996-08-07 | 1998-04-14 | The Regents Of The University Of California | Packaging cell lines for pseudotyped retroviral vectors |
| US6207455B1 (en) | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| JP4390860B2 (ja) | 1997-05-13 | 2009-12-24 | ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | レンチウイルスをベースにした遺伝子転移ベクター |
| US6136597A (en) | 1997-09-18 | 2000-10-24 | The Salk Institute For Biological Studies | RNA export element |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| JP2002538842A (ja) | 1999-03-16 | 2002-11-19 | デイナ−ファーバー キャンサー インスティチュート，インコーポレイテッド | 大量のスクリーニングのためのレンチウイルスベクター系 |
| ATE351916T1 (de) | 1999-10-12 | 2007-02-15 | Pasteur Institut | Lentivirale triplex-dns, und vektoren und rekombinante zellen, die lentivirale triplex-dns enthalten |
| US7939059B2 (en) | 2001-12-10 | 2011-05-10 | California Institute Of Technology | Method for the generation of antigen-specific lymphocytes |
| US7135339B2 (en) | 2003-11-20 | 2006-11-14 | University Of Iowa Research Foundation | Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) |
| EP1769078A1 (en) | 2004-07-01 | 2007-04-04 | VIRxSYS Corporation | Vector packaging cell line |
| JP2006085744A (ja) | 2004-09-14 | 2006-03-30 | Matsushita Electric Ind Co Ltd | 磁気記録再生装置及びそのテープスレッディング方法 |
| WO2007095201A2 (en) | 2006-02-15 | 2007-08-23 | The Regents Of The University Of California | Pseudotyped retroviral vectors and methods of use thereof |
| CA2651174A1 (en) | 2006-05-03 | 2007-11-15 | Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services | Chimeric t cell receptors and related materials and methods of use |
| US8293685B2 (en) | 2007-07-26 | 2012-10-23 | The Regents Of The University Of California | Methods for enhancing bacterial cell display of proteins and peptides |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| GB0920775D0 (en) | 2009-11-26 | 2010-01-13 | King S College | Cells |
| EP2895203A4 (en) | 2012-06-15 | 2016-09-28 | Imaginab Inc | ANTIGENBINDING CONSTRUCTS FOR CD3 |
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| WO2015017214A1 (en) | 2013-07-29 | 2015-02-05 | Bluebird Bio, Inc. | Multipartite signaling proteins and uses thereof |
| US10287354B2 (en) * | 2013-12-20 | 2019-05-14 | Novartis Ag | Regulatable chimeric antigen receptor |
| US20170081411A1 (en) | 2014-03-15 | 2017-03-23 | Novartis Ag | Regulatable chimeric antigen receptor |
| EP3593812A3 (en) | 2014-03-15 | 2020-05-27 | Novartis AG | Treatment of cancer using chimeric antigen receptor |
| DK3166968T3 (da) | 2014-05-02 | 2021-12-06 | Univ Pennsylvania | Sammensætninger og fremgangsmåder til kimæriske autoantistofreceptor-T-celler |
| GB201412494D0 (en) | 2014-07-14 | 2014-08-27 | Ospedale San Raffaele And Fond Telethon | Vector production |
| CN107531800B (zh) | 2014-07-25 | 2021-08-10 | 赛拉福柯蒂斯公司 | 用于嵌合抗原受体分子的调控表达的慢病毒载体 |
| TWI805109B (zh) | 2014-08-28 | 2023-06-11 | 美商奇諾治療有限公司 | 對cd19具專一性之抗體及嵌合抗原受體 |
| WO2016118775A1 (en) | 2015-01-21 | 2016-07-28 | Fred Hutchinson Cancer Research Center | Cocal envelope pseudotyped retroviral vector producer cells |
| JP7237449B2 (ja) | 2015-02-27 | 2023-03-13 | アイセル・ジーン・セラピューティクス・エルエルシー | 血液系腫瘍を標的としたキメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法 |
| GB201503500D0 (en) | 2015-03-02 | 2015-04-15 | Ucl Business Plc | Cell |
| EP3270943A4 (en) | 2015-03-16 | 2018-10-17 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Isolated peptides derived from the b7 ligand dimer interface and uses thereof |
| AU2016297014B2 (en) | 2015-07-21 | 2021-06-17 | Novartis Ag | Methods for improving the efficacy and expansion of immune cells |
| GB201514875D0 (en) | 2015-08-20 | 2015-10-07 | Autolus Ltd | Receptor |
| IL261713B2 (en) | 2016-03-19 | 2023-09-01 | F1 Oncology Inc | Methods and preparations for the transfer of lymphocytes and their regulated expansion |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| EP3458485B1 (en) * | 2016-05-19 | 2021-12-29 | The General Hospital Corporation | Tethered interleukin-2 to its receptor il-2rbeta, a platform to enhance natural killer and regulatory t cell activity |
| EP3512540A1 (en) | 2016-09-14 | 2019-07-24 | Université Catholique de Louvain | Modified vsv-g and vaccines thereof |
| JP7206214B2 (ja) | 2016-12-13 | 2023-01-17 | シアトル チルドレンズ ホスピタル （ディービーエイ シアトル チルドレンズ リサーチ インスティテュート） | インビトロ及びインビボで操作された細胞において発現された化学誘導シグナル伝達複合体の外因性薬物活性化の方法 |
| US11613574B2 (en) | 2017-01-10 | 2023-03-28 | The General Hospital Corporation | Methods and compositions relating to ex vivo culture and modulation of T cells |
| CN110612119B (zh) | 2017-02-07 | 2024-10-29 | 西雅图儿童医院（Dba西雅图儿童研究所） | 磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂 |
| CN110662839A (zh) | 2017-02-17 | 2020-01-07 | 珀杜研究基金会 | 用于细胞疗法的基于靶向性配体-有效负载的药物递送 |
| JP7178355B2 (ja) | 2017-02-28 | 2022-11-25 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための組成物および方法 |
| CN111479921B (zh) | 2017-09-18 | 2024-08-02 | 埃克苏马生物技术公司 | 用于以基因方式修饰且扩增淋巴细胞以及调节其活性的方法及组合物 |
| CA3083786A1 (en) | 2017-12-07 | 2019-06-13 | Dermavant Sciences GmbH | Topical ointment formulations of pde-4 inhibitor and their use in treating skin conditions |
| JP7549303B2 (ja) | 2018-01-22 | 2024-09-11 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞の使用方法 |
| SG11202007426XA (en) | 2018-02-06 | 2020-09-29 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| US20210038646A1 (en) | 2018-02-12 | 2021-02-11 | The General Hospital Corporation | Chimeric antigen receptors targeting the tumor microenvironment |
| CN112262214A (zh) | 2018-04-12 | 2021-01-22 | 优莫佳生物制药股份有限公司 | 病毒载体及包装细胞系 |
| KR20210074274A (ko) | 2018-08-06 | 2021-06-21 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 합텐 표지된 세포로의 키메라 항원 수용체 t 세포의 자극을 위한 방법 및 조성물 |
| KR20210042125A (ko) | 2018-08-07 | 2021-04-16 | 퍼듀 리서치 파운데이션 | Car t 세포의 회생 |
| WO2020106992A1 (en) | 2018-11-21 | 2020-05-28 | Umoja Biopharma, Inc. | Multicistronic vector for surface engineering lentiviral particles |
| PL3886894T3 (pl) | 2018-11-30 | 2024-07-01 | Juno Therapeutics, Inc. | Metody dawkowania i leczenia nowotworów b-komórkowych w adoptywnej terapii komórkowej |
| US20240122978A1 (en) | 2019-10-16 | 2024-04-18 | Umoja Biopharma, Inc. | Retroviral vector for univeral receptor therapy |
| WO2021242719A1 (en) | 2020-05-27 | 2021-12-02 | The Medical College Of Wisconsin, Inc. | Improved lentiviral vector transfer plasmid and methods of use |
| US11517814B2 (en) | 2020-09-03 | 2022-12-06 | Alan Chalmers | Flavour system |
| CA3199588A1 (en) | 2020-11-20 | 2022-05-27 | Andrew Scharenberg | Vector system for delivery of multiple polynucleotides and uses thereof |
| MX2023008831A (es) | 2021-01-27 | 2023-10-19 | Umoja Biopharma Inc | Lentivirus para generar células que expresan receptores de antígeno quimérico anti-cd19. |
| JP2025517138A (ja) | 2022-05-06 | 2025-06-03 | ウモジャ バイオファーマ インコーポレイテッド | 表面刺激分子を有するウイルス粒子 |
-
2019
- 2019-04-11 CN CN201980037729.7A patent/CN112262214A/zh active Pending
- 2019-04-11 CA CA3096458A patent/CA3096458A1/en active Pending
- 2019-04-11 AU AU2019252285A patent/AU2019252285B2/en active Active
- 2019-04-11 BR BR112020020887-6A patent/BR112020020887A2/pt unknown
- 2019-04-11 EP EP19719740.3A patent/EP3775231A2/en active Pending
- 2019-04-11 JP JP2021505621A patent/JP7721436B2/ja active Active
- 2019-04-11 US US17/046,701 patent/US12215337B2/en active Active
- 2019-04-11 SG SG11202009975TA patent/SG11202009975TA/en unknown
- 2019-04-11 WO PCT/US2019/026923 patent/WO2019200056A2/en not_active Ceased
-
2020
- 2020-10-11 IL IL277936A patent/IL277936A/en unknown
-
2024
- 2024-05-24 JP JP2024084707A patent/JP2024100972A/ja active Pending
- 2024-12-20 US US18/991,101 patent/US20250122532A1/en active Pending
- 2024-12-20 US US18/991,176 patent/US20250122533A1/en active Pending
-
2025
- 2025-09-25 AU AU2025237995A patent/AU2025237995A1/en active Pending
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