JP2024073531A5 - - Google Patents

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Publication number
JP2024073531A5
JP2024073531A5 JP2024038103A JP2024038103A JP2024073531A5 JP 2024073531 A5 JP2024073531 A5 JP 2024073531A5 JP 2024038103 A JP2024038103 A JP 2024038103A JP 2024038103 A JP2024038103 A JP 2024038103A JP 2024073531 A5 JP2024073531 A5 JP 2024073531A5
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JP
Japan
Prior art keywords
nucleic acid
polypeptide
variable domain
pichia host
immunoglobulin single
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JP2024038103A
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English (en)
Japanese (ja)
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JP2024073531A (ja
JP7849405B2 (ja
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Priority claimed from JP2018542263A external-priority patent/JP7540877B2/ja
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Publication of JP2024073531A5 publication Critical patent/JP2024073531A5/ja
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Publication of JP7849405B2 publication Critical patent/JP7849405B2/ja
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JP2024038103A 2016-02-12 2024-03-12 免疫グロブリン単一可変ドメインの生成方法 Active JP7849405B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662294470P 2016-02-12 2016-02-12
US62/294,470 2016-02-12
JP2018542263A JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法
PCT/EP2017/053034 WO2017137579A1 (en) 2016-02-12 2017-02-10 Method for the production of immunoglobulin single variable domains

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018542263A Division JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法

Publications (3)

Publication Number Publication Date
JP2024073531A JP2024073531A (ja) 2024-05-29
JP2024073531A5 true JP2024073531A5 (enExample) 2024-11-11
JP7849405B2 JP7849405B2 (ja) 2026-04-21

Family

ID=58018106

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018542263A Active JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法
JP2024038103A Active JP7849405B2 (ja) 2016-02-12 2024-03-12 免疫グロブリン単一可変ドメインの生成方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2018542263A Active JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法

Country Status (7)

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US (2) US10975141B2 (enExample)
EP (1) EP3414268A1 (enExample)
JP (2) JP7540877B2 (enExample)
CN (1) CN108699151B (enExample)
AU (2) AU2017216864B2 (enExample)
CA (1) CA3014443A1 (enExample)
WO (1) WO2017137579A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO2768984T3 (enExample) * 2015-11-12 2018-06-09
EP3414268A1 (en) 2016-02-12 2018-12-19 Ablynx NV Method for the production of immunoglobulin single variable domains
EP3778865A4 (en) 2018-03-26 2021-12-22 National University Corporation Kobe University Novel cell and method for making a protein of interest using it
EP4069733A1 (en) * 2019-12-06 2022-10-12 Ablynx N.V. POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING TNFalpha AND IL-23
CN110964113B (zh) * 2019-12-24 2021-09-03 北京纽安博生物技术有限公司 介导结合免疫球蛋白的单域抗体、由其构建的双功能抗体及其应用
JP7714233B2 (ja) * 2020-03-19 2025-07-29 国立大学法人神戸大学 内在性遺伝子の発現が増強された遺伝子組換え細胞の製造方法
MX2022012278A (es) * 2020-03-30 2022-10-27 Ablynx Nv Metodo para la produccion y purificacion de dominios variables unicos de inmunoglobulina multivalentes.
FR3120877B1 (fr) 2021-03-19 2025-03-14 Univ Toulouse 3 Paul Sabatier Cellule immunitaire comprenant un récepteur Fc à sa surface, et sur lequel est greffé une molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations
FR3120866B1 (fr) 2021-03-19 2025-02-28 Univ Toulouse 3 Paul Sabatier Molécule hybride comprenant un peptide citrulliné dérivé de la fibrine et un anticorps ou fragment d’anticorps se liant à CD38 et/ou CD138, et ses utilisations
FR3120865B1 (fr) 2021-03-19 2025-02-28 Univ Toulouse 3 Paul Sabatier Molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations
CN114920839B (zh) * 2022-06-17 2023-03-10 天津大学 特异性结合il-23的纳米抗体及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022855B1 (en) 2006-05-16 2015-08-19 Daiichi Sankyo Company, Limited High secretion production method of protein
US9212226B2 (en) 2008-05-16 2015-12-15 Ablynx N.V. Amino acid sequences directed against CXCR4 and other GPCRs and compounds comprising the same
CA2759370C (en) 2009-04-30 2020-02-11 Peter Schotte Method for the production of domain antibodies
US8440456B2 (en) * 2009-05-22 2013-05-14 Vib, Vzw Nucleic acids of Pichia pastoris and use thereof for recombinant production of proteins
WO2011161266A1 (en) 2010-06-25 2011-12-29 Ablynx Nv Improved immunoglobulin single variable domains and constructs thereof directed against cxcr4
AU2012234284B2 (en) * 2011-03-28 2015-10-08 Ablynx Nv Bispecific anti-CXCR7 immunoglobulin single variable domains
LT3248986T (lt) 2014-05-16 2022-03-25 Ablynx Nv Imunoglobulino kintami domenai
EP3414268A1 (en) 2016-02-12 2018-12-19 Ablynx NV Method for the production of immunoglobulin single variable domains

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