JP2024026104A5 - - Google Patents
Info
- Publication number
- JP2024026104A5 JP2024026104A5 JP2023195267A JP2023195267A JP2024026104A5 JP 2024026104 A5 JP2024026104 A5 JP 2024026104A5 JP 2023195267 A JP2023195267 A JP 2023195267A JP 2023195267 A JP2023195267 A JP 2023195267A JP 2024026104 A5 JP2024026104 A5 JP 2024026104A5
- Authority
- JP
- Japan
- Prior art keywords
- neonatal
- pharmaceutical composition
- pain
- convulsions
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862644932P | 2018-03-19 | 2018-03-19 | |
| US201862644902P | 2018-03-19 | 2018-03-19 | |
| US62/644,932 | 2018-03-19 | ||
| US62/644,902 | 2018-03-19 | ||
| US201862663438P | 2018-04-27 | 2018-04-27 | |
| US62/663,438 | 2018-04-27 | ||
| US201862697198P | 2018-07-12 | 2018-07-12 | |
| US62/697,198 | 2018-07-12 | ||
| JP2020551340A JP7757036B2 (ja) | 2018-03-19 | 2019-03-19 | Ｋｖ７チャネル活性化剤の構成および使用方法 |
| PCT/US2019/023039 WO2019183148A1 (en) | 2018-03-19 | 2019-03-19 | Kv7 channel activators compositions and methods of use |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551340A Division JP7757036B2 (ja) | 2018-03-19 | 2019-03-19 | Ｋｖ７チャネル活性化剤の構成および使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024026104A JP2024026104A (ja) | 2024-02-28 |
| JP2024026104A5 true JP2024026104A5 (https=) | 2026-01-22 |
Family
ID=67905138
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551340A Active JP7757036B2 (ja) | 2018-03-19 | 2019-03-19 | Ｋｖ７チャネル活性化剤の構成および使用方法 |
| JP2023195267A Pending JP2024026104A (ja) | 2018-03-19 | 2023-11-16 | Ｋｖ７チャネル活性化剤の構成および使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551340A Active JP7757036B2 (ja) | 2018-03-19 | 2019-03-19 | Ｋｖ７チャネル活性化剤の構成および使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US10851067B2 (https=) |
| EP (1) | EP3768677A4 (https=) |
| JP (2) | JP7757036B2 (https=) |
| KR (3) | KR102731128B1 (https=) |
| CN (6) | CN118955402A (https=) |
| AU (3) | AU2019239955B2 (https=) |
| BR (1) | BR112020018933A2 (https=) |
| CA (1) | CA3093976A1 (https=) |
| IL (2) | IL277419B2 (https=) |
| MX (2) | MX2020009693A (https=) |
| SG (1) | SG11202008030WA (https=) |
| WO (1) | WO2019183148A1 (https=) |
| ZA (1) | ZA202308070B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3572405T1 (sl) * | 2014-09-12 | 2023-12-29 | Biohaven Therapeutics Ltd. | Amidi benzoimidazol-1,2-il kot aktivatorji kanalov kv 7 |
| CN118955402A (zh) * | 2018-03-19 | 2024-11-15 | 诺普生物科学有限责任公司 | Kv7通道激活剂组合物和使用方法 |
| BR112022004847A2 (pt) * | 2019-09-17 | 2022-06-07 | Knopp Biosciences Llc | Método para tratar uma doença ou distúrbio de neurodesenvolvimento |
| CA3266454A1 (en) * | 2022-08-30 | 2024-03-07 | Biohaven Therapeutics Ltd. | POLYTHERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS |
| AU2023338196A1 (en) * | 2022-09-06 | 2025-04-10 | Biohaven Therapeutics Ltd. | Combination therapies including metal channel activators |
| KR20260049605A (ko) * | 2023-08-10 | 2026-04-14 | 바이오하벤 테라퓨틱스 리미티드 | Kv7.2/7.3 칼륨 채널 활성제의 서방형 제형 |
| IL326832A (en) * | 2023-09-15 | 2026-04-01 | Biohaven Therapeutics Ltd | Methods for treating epilepsy and related disorders using potent and selective potassium channel activators |
| WO2025103406A1 (zh) * | 2023-11-15 | 2025-05-22 | 南京明德新药研发有限公司 | 6并5杂芳基衍生物及其应用 |
| WO2025137661A1 (en) * | 2023-12-22 | 2025-06-26 | Biohaven Therapeutics Ltd. | Combination treatment of neurological disorders |
| US20260049061A1 (en) * | 2024-03-18 | 2026-02-19 | HUMANWELL PHARMACEUTICAL US, Inc. | Small molecules as kcnq2/3 (kv7.2/3) channel activators and their medical use thereof |
| WO2026042005A1 (en) | 2024-08-18 | 2026-02-26 | Biohaven Therapeutics Ltd. | Prodrugs of benzimidazol-1,2-yl amide compounds |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0772181B2 (ja) | 1989-06-26 | 1995-08-02 | 株式会社大塚製薬工場 | ベンズイミダゾール誘導体 |
| JPH0772181A (ja) | 1993-09-03 | 1995-03-17 | Advantest Corp | 電位波形測定方法および装置 |
| GB9413724D0 (en) | 1994-07-07 | 1994-08-24 | Wellcome Found | Therapeutic nucleosides |
| US6855714B2 (en) | 2001-07-06 | 2005-02-15 | Schering Aktiengesellschaft | 1-alkyl-2-aryl-benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives |
| SE0301701D0 (sv) | 2003-06-10 | 2003-06-10 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
| WO2007017764A2 (en) * | 2005-05-18 | 2007-02-15 | Neuraxon, Inc. | Substituted benzimidazole compounds with dual nos inhibitory activity and muopioid agonist activity |
| CN101516873A (zh) * | 2006-10-03 | 2009-08-26 | 神经研究公司 | 用作钾通道调节剂的吲唑基衍生物 |
| EP2186804B1 (en) | 2007-08-10 | 2015-06-17 | Nippon Soda Co., Ltd. | Nitrogen-containing heterocyclic compound and pest control agent |
| TWI482768B (zh) | 2007-11-22 | 2015-05-01 | Zenyaku Kogyo Kk | 雜環化合物之非晶質體、含有其之固體分散體、藥劑及其製法 |
| GB0723794D0 (en) | 2007-12-05 | 2008-01-16 | Lectus Therapeutics Ltd | Potassium ion channel modulators and uses thereof |
| AU2008343813B2 (en) | 2007-12-19 | 2012-04-12 | Amgen Inc. | Inhibitors of PI3 kinase |
| WO2010051819A1 (en) | 2008-11-10 | 2010-05-14 | Neurosearch A/S | Novel 2,3-diamino-quinazolinone derivatives and their medical use |
| US8232273B2 (en) | 2008-12-19 | 2012-07-31 | Genentech, Inc. | Heterocyclic compounds and methods of use |
| CA2804165C (en) | 2010-07-08 | 2015-02-24 | Pfizer Inc. | Piperidinyl pyrimidine amides as kv7 potassium channel openers |
| CN103168032A (zh) | 2010-08-05 | 2013-06-19 | 安美基公司 | 抑制间变性淋巴瘤激酶的苯并咪唑和氮杂苯并咪唑化合物 |
| US9650376B2 (en) | 2013-03-15 | 2017-05-16 | Knopp Biosciences Llc | Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators |
| WO2015023958A1 (en) * | 2013-08-15 | 2015-02-19 | The University Of Kansas | Toll-like receptor agonists |
| SI3572405T1 (sl) | 2014-09-12 | 2023-12-29 | Biohaven Therapeutics Ltd. | Amidi benzoimidazol-1,2-il kot aktivatorji kanalov kv 7 |
| CN118955402A (zh) * | 2018-03-19 | 2024-11-15 | 诺普生物科学有限责任公司 | Kv7通道激活剂组合物和使用方法 |
| BR112022004847A2 (pt) * | 2019-09-17 | 2022-06-07 | Knopp Biosciences Llc | Método para tratar uma doença ou distúrbio de neurodesenvolvimento |
-
2019
- 2019-03-19 CN CN202410835028.0A patent/CN118955402A/zh active Pending
- 2019-03-19 AU AU2019239955A patent/AU2019239955B2/en active Active
- 2019-03-19 IL IL277419A patent/IL277419B2/en unknown
- 2019-03-19 BR BR112020018933-2A patent/BR112020018933A2/pt unknown
- 2019-03-19 CA CA3093976A patent/CA3093976A1/en active Pending
- 2019-03-19 US US16/358,642 patent/US10851067B2/en active Active
- 2019-03-19 KR KR1020207029659A patent/KR102731128B1/ko active Active
- 2019-03-19 KR KR1020247037753A patent/KR102868652B1/ko active Active
- 2019-03-19 CN CN202410805545.3A patent/CN118955400A/zh active Pending
- 2019-03-19 CN CN202410805542.XA patent/CN119118926A/zh active Pending
- 2019-03-19 CN CN201980033266.7A patent/CN112771039A/zh active Pending
- 2019-03-19 JP JP2020551340A patent/JP7757036B2/ja active Active
- 2019-03-19 CN CN202410840828.1A patent/CN118955403A/zh active Pending
- 2019-03-19 WO PCT/US2019/023039 patent/WO2019183148A1/en not_active Ceased
- 2019-03-19 KR KR1020257032902A patent/KR20250150168A/ko active Pending
- 2019-03-19 SG SG11202008030WA patent/SG11202008030WA/en unknown
- 2019-03-19 EP EP19772264.8A patent/EP3768677A4/en active Pending
- 2019-03-19 MX MX2020009693A patent/MX2020009693A/es unknown
- 2019-03-19 CN CN202410827103.9A patent/CN118955401A/zh active Pending
- 2019-03-19 IL IL310136A patent/IL310136A/en unknown
-
2020
- 2020-09-17 MX MX2023001153A patent/MX2023001153A/es unknown
- 2020-10-22 US US17/077,068 patent/US11261162B2/en active Active
-
2022
- 2022-01-07 US US17/570,536 patent/US11724990B2/en active Active
-
2023
- 2023-06-20 US US18/338,096 patent/US12286408B2/en active Active
- 2023-08-21 ZA ZA2023/08070A patent/ZA202308070B/en unknown
- 2023-11-16 JP JP2023195267A patent/JP2024026104A/ja active Pending
- 2023-11-17 AU AU2023266373A patent/AU2023266373B2/en active Active
-
2024
- 2024-04-17 AU AU2024202496A patent/AU2024202496A1/en active Pending
-
2025
- 2025-03-29 US US19/094,862 patent/US20260062389A1/en active Pending
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