|
US20020102257A1
(en)
|
1998-09-21 |
2002-08-01 |
Leslie Sid Johnson |
Human-murine chimeric antibodies against respiratory syncytial virus
|
|
US5604090A
(en)
|
1994-06-06 |
1997-02-18 |
Fred Hutchinson Cancer Research Center |
Method for increasing transduction of cells by adeno-associated virus vectors
|
|
AU2001238079A1
(en)
|
2000-02-09 |
2001-08-20 |
Med Immune, Inc. |
Antibody gene therapy with adeno-associated viral vectors
|
|
KR100545945B1
(ko)
*
|
2000-07-03 |
2006-01-25 |
갈라 디자인, 인크. |
발현 벡터
|
|
AU7658101A
(en)
|
2000-07-28 |
2002-02-13 |
Cytos Biotechnology Ag |
Compositions for inducing self-specific anti-ige antibodies and uses thereof
|
|
DE10113776B4
(de)
*
|
2001-03-21 |
2012-08-09 |
"Iba Gmbh" |
Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins
|
|
US7696322B2
(en)
*
|
2003-07-28 |
2010-04-13 |
Catalent Pharma Solutions, Inc. |
Fusion antibodies
|
|
WO2006115800A2
(en)
*
|
2005-04-15 |
2006-11-02 |
The Regents Of The University Of California |
Enhanced wound healing utilizing an anti-her2 antibody coupled to a tnf alpha
|
|
AU2007245164A1
(en)
*
|
2006-03-28 |
2007-11-08 |
Biogen Idec Ma Inc. |
Anti-IGF-IR antibodies and uses thereof
|
|
US20120102582A1
(en)
|
2009-04-03 |
2012-04-26 |
Haynes Barton F |
Mouse models
|
|
DK3622815T3
(da)
|
2009-07-08 |
2023-06-26 |
Kymab Ltd |
Gnavermodeller og terapeutiske molekyler
|
|
AU2010310895A1
(en)
|
2009-10-23 |
2012-05-03 |
Garvan Institute Of Medical Research |
Modified variable domain molecules and methods for producing and using same
|
|
US9074223B2
(en)
*
|
2010-01-08 |
2015-07-07 |
Immusoft Corporation |
Vectors and methods for transducing B cells
|
|
BR112012031638B1
(pt)
|
2010-07-09 |
2021-01-12 |
Janssen Vaccines & Prevention B.V. |
anticorpo anti-rsv ou fragmento de ligação de antígeno do mesmo, anticorpo multivalente, composição farmacêutica, uso de anticorpo ou fragmento de ligação de antígeno, método de detectar infecção por rsv, e, ácido nucleico isolado
|
|
US8637035B2
(en)
|
2010-07-16 |
2014-01-28 |
Academia Sinica |
Anti-dengue virus antibodies
|
|
US8637024B2
(en)
|
2010-11-12 |
2014-01-28 |
The Rockefeller University |
Fusion antibodies for HIV therapy
|
|
EP2663334A4
(en)
|
2011-01-10 |
2016-01-13 |
Univ Emory |
ANTIBODIES AGAINST INFLUENZA
|
|
NO2748201T3
(cg-RX-API-DMAC7.html)
|
2011-08-23 |
2018-05-12 |
|
|
|
GB201122047D0
(en)
*
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
|
CA2867522A1
(en)
|
2012-03-16 |
2013-09-19 |
University Of Rochester |
Methods of predicting clinical outcome of chronic lymphocytic leukemia
|
|
WO2013148256A2
(en)
|
2012-03-27 |
2013-10-03 |
Dana-Farber Cancer Institute, Inc. |
Compositions, kits, and methods for the generation of immunoglobulin sequences
|
|
AU2013293270B2
(en)
|
2012-07-25 |
2018-08-16 |
Massachusetts Institute Of Technology |
Inducible DNA binding proteins and genome perturbation tools and applications thereof
|
|
US20140186843A1
(en)
|
2012-12-12 |
2014-07-03 |
Massachusetts Institute Of Technology |
Methods, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
|
|
CN113355357B
(zh)
|
2012-12-12 |
2024-12-03 |
布罗德研究所有限公司 |
对用于序列操纵的改进的系统、方法和酶组合物进行的工程化和优化
|
|
WO2014093709A1
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Methods, models, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
|
|
US20140310830A1
(en)
|
2012-12-12 |
2014-10-16 |
Feng Zhang |
CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes
|
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
|
EP3031921B1
(en)
|
2012-12-12 |
2025-03-12 |
The Broad Institute, Inc. |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
|
|
EP2931899A1
(en)
|
2012-12-12 |
2015-10-21 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof
|
|
IL239344B2
(en)
|
2012-12-12 |
2024-06-01 |
Broad Inst Inc |
Systems engineering, methods and optimal guiding components for sequence manipulation
|
|
EP2840140B2
(en)
|
2012-12-12 |
2023-02-22 |
The Broad Institute, Inc. |
Crispr-Cas based method for mutation of prokaryotic cells
|
|
WO2014093655A2
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
|
|
US11332719B2
(en)
|
2013-03-15 |
2022-05-17 |
The Broad Institute, Inc. |
Recombinant virus and preparations thereof
|
|
WO2014141192A1
(en)
*
|
2013-03-15 |
2014-09-18 |
Erasmus University Medical Center |
Generation of heavy chain-only antibodies
|
|
MX374532B
(es)
|
2013-06-17 |
2025-03-06 |
Broad Inst Inc |
Suministro, uso y aplicaciones terapéuticas de los sistemas y composiciones crispr-cas, para actuar sobre trastornos y enfermedades utilizando componentes víricos.
|
|
WO2014204724A1
(en)
|
2013-06-17 |
2014-12-24 |
The Broad Institute Inc. |
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
|
|
CN105492611A
(zh)
|
2013-06-17 |
2016-04-13 |
布罗德研究所有限公司 |
用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物
|
|
CN105683379A
(zh)
|
2013-06-17 |
2016-06-15 |
布罗德研究所有限公司 |
用于对有丝分裂后细胞的疾病和障碍进行靶向和建模的系统、方法和组合物的递送、工程化和优化
|
|
WO2014204723A1
(en)
|
2013-06-17 |
2014-12-24 |
The Broad Institute Inc. |
Oncogenic models based on delivery and use of the crispr-cas systems, vectors and compositions
|
|
RU2716420C2
(ru)
|
2013-06-17 |
2020-03-11 |
Те Брод Инститьют Инк. |
Доставка и применение систем crispr-cas, векторов и композиций для целенаправленного воздействия и терапии в печени
|
|
EP3725885A1
(en)
|
2013-06-17 |
2020-10-21 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof
|
|
JP6595988B2
(ja)
|
2013-07-19 |
2019-10-23 |
ヴィブ ブイゼットダブリュー |
ターゲットされる修飾ｔｎｆファミリーメンバー
|
|
WO2015065964A1
(en)
|
2013-10-28 |
2015-05-07 |
The Broad Institute Inc. |
Functional genomics using crispr-cas systems, compositions, methods, screens and applications thereof
|
|
SG10201804975PA
(en)
*
|
2013-12-12 |
2018-07-30 |
Broad Inst Inc |
Delivery, Use and Therapeutic Applications of the Crispr-Cas Systems and Compositions for HBV and Viral Diseases and Disorders
|
|
JP6793547B2
(ja)
|
2013-12-12 |
2020-12-02 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
最適化機能ＣＲＩＳＰＲ−Ｃａｓ系による配列操作のための系、方法および組成物
|
|
WO2015089427A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Crispr-cas systems and methods for altering expression of gene products, structural information and inducible modular cas enzymes
|
|
EP3470089A1
(en)
|
2013-12-12 |
2019-04-17 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
|
|
JP6712948B2
(ja)
|
2013-12-12 |
2020-06-24 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
組成物、及びヌクレオチドリピート障害におけるｃｒｉｓｐｒ−ｃａｓ系の使用方法
|
|
EP3080259B1
(en)
|
2013-12-12 |
2023-02-01 |
The Broad Institute, Inc. |
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
|
|
JP7103750B2
(ja)
|
2013-12-12 |
2022-07-20 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
ゲノム編集のためのＣＲＩＳＰＲ－Ｃａｓ系及び組成物の送達、使用及び治療適用
|
|
WO2015089364A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Crystal structure of a crispr-cas system, and uses thereof
|
|
WO2015120056A1
(en)
|
2014-02-04 |
2015-08-13 |
Biogen Ma Inc. |
Use of cation-exchange chromatography in the flow-through mode to enrich post-translational modifications
|
|
ES2755957T3
(es)
|
2014-03-31 |
2020-04-24 |
Univ Texas |
Anticuerpos de tos ferina humanizados y usos de los mismos
|
|
US11897921B2
(en)
|
2014-12-09 |
2024-02-13 |
New York University |
Propeptide fusion comprising a mutated clostridium botulinum neurotoxin and a VHH domain
|
|
CA2981077A1
(en)
|
2015-04-03 |
2016-10-06 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
|
US9790490B2
(en)
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
|
US12110490B2
(en)
|
2015-12-18 |
2024-10-08 |
The Broad Institute, Inc. |
CRISPR enzymes and systems
|
|
JP6914274B2
(ja)
|
2016-01-22 |
2021-08-04 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
Ｃｒｉｓｐｒｃｐｆ１の結晶構造
|