JP2024001208A5 - - Google Patents
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- Publication number
- JP2024001208A5 JP2024001208A5 JP2023174585A JP2023174585A JP2024001208A5 JP 2024001208 A5 JP2024001208 A5 JP 2024001208A5 JP 2023174585 A JP2023174585 A JP 2023174585A JP 2023174585 A JP2023174585 A JP 2023174585A JP 2024001208 A5 JP2024001208 A5 JP 2024001208A5
- Authority
- JP
- Japan
- Prior art keywords
- dementia
- subject
- adm
- seq
- adrenomedullin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18155682 | 2018-02-08 | ||
| EP18155682.0 | 2018-02-08 | ||
| PCT/EP2019/052982 WO2019154900A1 (en) | 2018-02-08 | 2019-02-07 | Adrenomedullin (adm) for diagnosis and/or prediction of dementia and anti-adrenomedullin binder for use in therapy or prevention of dementia |
| JP2020542645A JP2021513077A (ja) | 2018-02-08 | 2019-02-07 | 認知症の診断および／または予測のためのアドレノメデュリン（ａｄｍ）、ならびに認知症の治療または予防における使用のための抗アドレノメデュリンバインダー |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542645A Division JP2021513077A (ja) | 2018-02-08 | 2019-02-07 | 認知症の診断および／または予測のためのアドレノメデュリン（ａｄｍ）、ならびに認知症の治療または予防における使用のための抗アドレノメデュリンバインダー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024001208A JP2024001208A (ja) | 2024-01-09 |
| JP2024001208A5 true JP2024001208A5 (https=) | 2025-10-16 |
Family
ID=61188647
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542645A Pending JP2021513077A (ja) | 2018-02-08 | 2019-02-07 | 認知症の診断および／または予測のためのアドレノメデュリン（ａｄｍ）、ならびに認知症の治療または予防における使用のための抗アドレノメデュリンバインダー |
| JP2023174585A Pending JP2024001208A (ja) | 2018-02-08 | 2023-10-06 | 認知症の診断および／または予測のためのアドレノメデュリン（ａｄｍ）、ならびに認知症の治療または予防における使用のための抗アドレノメデュリンバインダー |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542645A Pending JP2021513077A (ja) | 2018-02-08 | 2019-02-07 | 認知症の診断および／または予測のためのアドレノメデュリン（ａｄｍ）、ならびに認知症の治療または予防における使用のための抗アドレノメデュリンバインダー |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20210302440A1 (https=) |
| EP (1) | EP3749959A1 (https=) |
| JP (2) | JP2021513077A (https=) |
| KR (1) | KR102717599B1 (https=) |
| CN (2) | CN111902721B (https=) |
| AU (1) | AU2019219071A1 (https=) |
| BR (1) | BR112020014940A2 (https=) |
| CA (1) | CA3090736A1 (https=) |
| IL (1) | IL276564A (https=) |
| MX (1) | MX421834B (https=) |
| SG (1) | SG11202006686SA (https=) |
| WO (1) | WO2019154900A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220146538A (ko) | 2020-02-26 | 2022-11-01 | 페아엠 테라그노스틱스 게엠베하 | 치료 목적을 위한 펩티딜글리신 알파-아미드화 모노옥시게나제 (pam)의 용도 |
| CN115280148A (zh) | 2020-02-26 | 2022-11-01 | Pam治疗诊断有限公司 | 测定肽酰甘氨酸α-酰胺化单加氧酶(PAM)的方法及其用于诊断目的的用途 |
| EP3871689A1 (en) * | 2020-02-26 | 2021-09-01 | sphingotec GmbH | Anti-adm-antibodies binding to the free n-terminus for accelerated transition of adm-gly to bio-adm in patients with adm-gly/ bio-adm ratio above a threshold and combination with vitamin c |
| US20210285949A1 (en) | 2020-03-16 | 2021-09-16 | Sphingotec Gmbh | Pro-adrenomedullin or fragment thereof in patients infected with corona virus and treatments with binder against adrenomedullin |
| CN120731367A (zh) | 2023-03-17 | 2025-09-30 | Pam治疗诊断有限公司 | 肽基甘氨酸α-酰胺化单加氧酶（PAM）的测定方法及其诊断用途 |
| WO2025133203A1 (en) | 2023-12-22 | 2025-06-26 | Pam Theragnostics Gmbh | Compounds and methods for a long-lasting pam |
| WO2025133225A1 (en) | 2023-12-22 | 2025-06-26 | Pam Theragnostics Gmbh | Pharmaceutical combination of peptide-gly and peptidylglycine alpha-amidating monooxygenase (pam) |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP1690934A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| EP0585287B1 (en) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| CA2124967C (en) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| JP2774769B2 (ja) | 1993-04-26 | 1998-07-09 | 賢治 寒川 | アドレノメデュリン |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| RU2004109222A (ru) | 2001-08-30 | 2005-10-20 | Байорексис Фармасьютикал Корпорейшн (Us) | Слитые белки модифицированного трансферрина |
| WO2005040229A2 (en) | 2003-10-24 | 2005-05-06 | Avidia, Inc. | Ldl receptor class a and egf domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| US8278262B2 (en) | 2004-09-21 | 2012-10-02 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| DE102005036094A1 (de) * | 2005-08-01 | 2007-02-08 | B.R.A.H.M.S Ag | In vitro Verfahren zur Diagnose von neurodegenerativen Erkrankungen |
| CA2620738C (en) | 2005-08-31 | 2010-10-12 | Ezaki Glico Co., Ltd. | Tablet for removing tongue coating |
| DE102006027818A1 (de) * | 2006-06-16 | 2007-12-20 | B.R.A.H.M.S. Aktiengesellschaft | In vitro Multiparameter-Bestimmungsverfahren zur Diagnose und Frühdiagnose von neurodegenerativen Erkrankungen |
| DE102006060112A1 (de) | 2006-12-20 | 2008-06-26 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM |
| DK2231860T3 (da) | 2007-12-19 | 2011-12-05 | Affibody Ab | Polypeptid afledt protein A og i stand til at binde PDGF |
| US20110039343A1 (en) * | 2008-02-01 | 2011-02-17 | Brahms Aktiengesellschaft | Method for the identification of patients in need of therapy having minor cognitive disorders and the treatment of such patients |
| EP3785735A1 (en) | 2008-11-03 | 2021-03-03 | Molecular Partners AG | Binding proteins inhibiting the vegf-a receptor interaction |
| MX2012002428A (es) | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| AU2010332932B2 (en) | 2009-12-14 | 2013-01-17 | Navigo Proteins Gmbh | Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin |
| RU2569745C2 (ru) | 2010-06-08 | 2015-11-27 | Пиерис АГ | Мутеины липокалина слезы, связывающие альфа il-4 r |
| FR2964103B1 (fr) * | 2010-08-30 | 2018-11-23 | Universite D'aix-Marseille | Anticorps se liant a l'adrenomedulline et aux recepteurs de l'adrenomedulline et leurs utilisations comme medicament |
| DK2780717T3 (en) * | 2011-11-16 | 2017-02-13 | Sphingotec Gmbh | ADRENOMEDULLINASSAYS AND METHODS FOR DETERMINING MODERN ADRENOMEDULLIN |
| PL2594588T3 (pl) * | 2011-11-16 | 2014-11-28 | Adrenomed Ag | Przeciwciało przeciwko adrenomedulinie (ADM) lub fragment przeciwciała anty-ADM lub szkielet białkowy niestanowiący Ig anty-ADM do zastosowania w terapii |
| US20160230227A1 (en) * | 2012-12-21 | 2016-08-11 | The New York Stem Cell Foundation | Methods of treating alzheimer's disease |
| EP4231018A3 (en) * | 2016-07-08 | 2023-11-15 | SphingoTec GmbH | Adrenomedullin for assessing congestion in a subject with acute heart failure |
-
2019
- 2019-02-07 US US16/968,483 patent/US20210302440A1/en active Pending
- 2019-02-07 CA CA3090736A patent/CA3090736A1/en active Pending
- 2019-02-07 JP JP2020542645A patent/JP2021513077A/ja active Pending
- 2019-02-07 KR KR1020207025729A patent/KR102717599B1/ko active Active
- 2019-02-07 SG SG11202006686SA patent/SG11202006686SA/en unknown
- 2019-02-07 BR BR112020014940-3A patent/BR112020014940A2/pt not_active IP Right Cessation
- 2019-02-07 AU AU2019219071A patent/AU2019219071A1/en not_active Abandoned
- 2019-02-07 WO PCT/EP2019/052982 patent/WO2019154900A1/en not_active Ceased
- 2019-02-07 EP EP19702467.2A patent/EP3749959A1/en active Pending
- 2019-02-07 CN CN201980012542.1A patent/CN111902721B/zh active Active
- 2019-02-07 CN CN202411684173.XA patent/CN119770645A/zh active Pending
- 2019-02-07 MX MX2020008345A patent/MX421834B/es unknown
-
2020
- 2020-08-06 IL IL276564A patent/IL276564A/en unknown
-
2022
- 2022-12-30 US US18/148,633 patent/US20230221339A1/en active Pending
-
2023
- 2023-10-06 JP JP2023174585A patent/JP2024001208A/ja active Pending
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