JP2023553938A5 - - Google Patents

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Publication number
JP2023553938A5
JP2023553938A5 JP2023535346A JP2023535346A JP2023553938A5 JP 2023553938 A5 JP2023553938 A5 JP 2023553938A5 JP 2023535346 A JP2023535346 A JP 2023535346A JP 2023535346 A JP2023535346 A JP 2023535346A JP 2023553938 A5 JP2023553938 A5 JP 2023553938A5
Authority
JP
Japan
Prior art keywords
antigen
binding fragment
antibody
sfrp2
humanized anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023535346A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023553938A (ja
JP7747350B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/062854 external-priority patent/WO2022125927A1/en
Publication of JP2023553938A publication Critical patent/JP2023553938A/ja
Publication of JP2023553938A5 publication Critical patent/JP2023553938A5/ja
Application granted granted Critical
Publication of JP7747350B2 publication Critical patent/JP7747350B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023535346A 2020-12-11 2021-12-10 Sfrp2アンタゴニストを含む組成物及び方法 Active JP7747350B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063124345P 2020-12-11 2020-12-11
US63/124,345 2020-12-11
PCT/US2021/062854 WO2022125927A1 (en) 2020-12-11 2021-12-10 Compositions and methods comprising sfrp2 antagonists

Publications (3)

Publication Number Publication Date
JP2023553938A JP2023553938A (ja) 2023-12-26
JP2023553938A5 true JP2023553938A5 (https=) 2024-12-18
JP7747350B2 JP7747350B2 (ja) 2025-10-01

Family

ID=81974701

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023535346A Active JP7747350B2 (ja) 2020-12-11 2021-12-10 Sfrp2アンタゴニストを含む組成物及び方法

Country Status (10)

Country Link
US (2) US11873333B2 (https=)
EP (1) EP4259203A4 (https=)
JP (1) JP7747350B2 (https=)
KR (1) KR102934264B1 (https=)
CN (1) CN116744970A (https=)
AU (1) AU2021396381A1 (https=)
CA (1) CA3201893A1 (https=)
IL (1) IL303600A (https=)
MX (1) MX2023006777A (https=)
WO (1) WO2022125927A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102934264B1 (ko) 2020-12-11 2026-03-05 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 Sfrp2 길항제를 포함하는 조성물 및 방법
WO2025076318A1 (en) * 2023-10-06 2025-04-10 Musc Foundation For Research Development Compositions for modulating the kras pathway and methods of use thereof
CN117756910A (zh) * 2023-12-22 2024-03-26 首都医科大学附属北京口腔医院 Sfrp2功能多肽及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
EP0216846B2 (en) 1985-04-01 1995-04-26 Celltech Limited Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
MX9204374A (es) 1991-07-25 1993-03-01 Idec Pharma Corp Anticuerpo recombinante y metodo para su produccion.
US6174666B1 (en) 1992-03-27 2001-01-16 The United States Of America As Represented By The Department Of Health And Human Services Method of eliminating inhibitory/instability regions from mRNA
US20040014194A1 (en) 2002-03-27 2004-01-22 Schering Corporation Beta-secretase crystals and methods for preparing and using the same
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
EP3124497B1 (en) 2007-09-14 2020-04-15 Adimab, LLC Rationally designed, synthetic antibody libraries and uses therefor
JP2011523551A (ja) 2008-05-15 2011-08-18 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 血管形成の調節の新規ターゲット
WO2011119524A1 (en) 2010-03-22 2011-09-29 The University Of North Carolina At Chapel Hill Novel targets for regulation of angiogenesis
KR102318383B1 (ko) 2010-07-16 2021-10-27 아디맵 엘엘씨 항체 라이브러리
JP6072771B2 (ja) 2011-04-20 2017-02-01 メディミューン,エルエルシー B7−h1およびpd−1に結合する抗体およびその他の分子
WO2015038882A1 (en) * 2013-09-13 2015-03-19 The University Of North Carolina At Chapel Hill Methods and compositions for tumor vasculature imaging and targeted therapy
KR102934264B1 (ko) 2020-12-11 2026-03-05 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 Sfrp2 길항제를 포함하는 조성물 및 방법

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