JP2023553697A5 - - Google Patents

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Publication number
JP2023553697A5
JP2023553697A5 JP2023536866A JP2023536866A JP2023553697A5 JP 2023553697 A5 JP2023553697 A5 JP 2023553697A5 JP 2023536866 A JP2023536866 A JP 2023536866A JP 2023536866 A JP2023536866 A JP 2023536866A JP 2023553697 A5 JP2023553697 A5 JP 2023553697A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
acid sequence
isvd
specifically binds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023536866A
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English (en)
Japanese (ja)
Other versions
JP7820383B2 (ja
JP2023553697A (ja
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Publication date
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Priority claimed from PCT/EP2021/086559 external-priority patent/WO2022129560A1/en
Publication of JP2023553697A publication Critical patent/JP2023553697A/ja
Publication of JP2023553697A5 publication Critical patent/JP2023553697A5/ja
Priority to JP2026020000A priority Critical patent/JP2026103881A/ja
Application granted granted Critical
Publication of JP7820383B2 publication Critical patent/JP7820383B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023536866A 2020-12-18 2021-12-17 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド Active JP7820383B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026020000A JP2026103881A (ja) 2020-12-18 2026-02-10 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063127224P 2020-12-18 2020-12-18
US63/127,224 2020-12-18
EP20306633.7 2020-12-21
EP20306633 2020-12-21
PCT/EP2021/086559 WO2022129560A1 (en) 2020-12-18 2021-12-17 Polypeptides comprising immunoglobulin single variable domains targeting glypican-3 and t cell receptor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026020000A Division JP2026103881A (ja) 2020-12-18 2026-02-10 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド

Publications (3)

Publication Number Publication Date
JP2023553697A JP2023553697A (ja) 2023-12-25
JP2023553697A5 true JP2023553697A5 (enExample) 2024-10-25
JP7820383B2 JP7820383B2 (ja) 2026-02-25

Family

ID=79283159

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023536866A Active JP7820383B2 (ja) 2020-12-18 2021-12-17 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド
JP2026020000A Pending JP2026103881A (ja) 2020-12-18 2026-02-10 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2026020000A Pending JP2026103881A (ja) 2020-12-18 2026-02-10 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド

Country Status (10)

Country Link
US (1) US11932702B2 (enExample)
EP (1) EP4262985A1 (enExample)
JP (2) JP7820383B2 (enExample)
KR (1) KR20230123495A (enExample)
AU (1) AU2021399955A1 (enExample)
CA (1) CA3205422A1 (enExample)
CO (1) CO2023009231A2 (enExample)
IL (1) IL303783A (enExample)
MX (1) MX2023007308A (enExample)
WO (1) WO2022129560A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3141978A1 (en) 2011-06-23 2012-12-27 Ablynx Nv Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
HRP20191800T1 (hr) * 2015-05-13 2019-12-27 Ablynx N.V. Polipeptidi koji regrutiraju t stanice koji se temelje na tcr alfa/beta reaktivnosti
CN119630705A (zh) * 2022-06-14 2025-03-14 阿布林克斯有限公司 靶向t细胞受体的免疫球蛋白单可变结构域
US20260191905A1 (en) * 2022-12-01 2026-07-09 Modernatx, Inc. Gpc3-specific antibodies, binding domains, and related proteins and uses thereof
US20240415974A1 (en) 2022-12-23 2024-12-19 Ablynx N.V. Protein-based conjugation carriers
KR20260068087A (ko) 2023-09-04 2026-05-13 사노피 글리피칸-3-발현 종양의 치료에 사용하기 위한 폴리펩티드
WO2025061919A1 (en) * 2023-09-22 2025-03-27 Ablynx Nv Bi- and multivalent albumin binders
WO2025262150A2 (en) 2024-06-18 2025-12-26 Ablynx Nv Antibody-recruiting molecules
WO2026145795A1 (zh) * 2025-01-06 2026-07-09 湖南中晟全肽生物科技股份有限公司 一种gpc3靶向结合多肽及其药物偶联物与应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69334275D1 (de) 1992-08-21 2009-05-20 Univ Bruxelles Immunoglobuline ohne Leichtkette
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
DK1027439T3 (da) 1997-10-27 2010-05-10 Bac Ip Bv Multivalente antigenbindende proteiner
NZ540194A (en) 2002-11-08 2008-07-31 Ablynx Nv Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
AU2005256113B2 (en) 2004-07-09 2011-02-10 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
AU2006249144B2 (en) 2005-05-18 2011-11-17 Ablynx Nv Improved NanobodiesTM against Tumor Necrosis Factor-alpha
AU2007237501A1 (en) 2006-04-14 2007-10-25 Ablynx N.V. DP-78-like nanobodies
JP2010500876A (ja) 2006-08-18 2010-01-14 アブリンクス エン.ヴェー. Il−6媒介性シグナル伝達に関連する疾患及び障害の治療のための、il−6rに指向性を有するアミノ酸配列及びこれを含むポリペプチド
AU2008275985B2 (en) * 2007-07-17 2013-09-19 E. R. Squibb & Sons, L.L.C. Monoclonal antibodies against Glypican-3
AU2010336277B2 (en) 2009-12-25 2015-02-19 Chugai Seiyaku Kabushiki Kaisha Polypeptide modification method for purifying polypeptide multimers
CA3141978A1 (en) 2011-06-23 2012-12-27 Ablynx Nv Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
LT3466972T (lt) 2011-06-23 2026-06-25 Ablynx Nv Serumo albuminą surišantys baltymai
LT3248986T (lt) 2014-05-16 2022-03-25 Ablynx Nv Imunoglobulino kintami domenai
MA40764A (fr) 2014-09-26 2017-08-01 Chugai Pharmaceutical Co Ltd Agent thérapeutique induisant une cytotoxicité
HRP20191800T1 (hr) 2015-05-13 2019-12-27 Ablynx N.V. Polipeptidi koji regrutiraju t stanice koji se temelje na tcr alfa/beta reaktivnosti
HUE057241T2 (hu) 2015-11-13 2022-04-28 Ablynx Nv Javított, szérumalbumint kötõ immunoglobulin variábilis domének
AU2016357460B2 (en) 2015-11-18 2023-07-27 Ablynx Nv Improved serum albumin binders
EP3431102A4 (en) 2016-03-14 2019-09-25 Chugai Seiyaku Kabushiki Kaisha CELL DAMAGING THERAPEUTIC MEDICAMENT FOR USE IN CANCER THERAPY
US11840569B2 (en) * 2016-11-16 2023-12-12 Ablynx N.V. T cell recruiting polypeptides capable of binding CD123 and TCR alpha/beta
WO2018104444A1 (en) 2016-12-07 2018-06-14 Ablynx Nv Improved serum albumin binding immunoglobulin single variable domains
EP3571224B1 (en) 2017-01-17 2024-08-07 Ablynx NV Improved serum albumin binders
EP4442709A3 (en) 2017-01-17 2024-12-25 Ablynx NV Improved serum albumin binders

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