JP2023551982A5 - - Google Patents

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Publication number
JP2023551982A5
JP2023551982A5 JP2023534301A JP2023534301A JP2023551982A5 JP 2023551982 A5 JP2023551982 A5 JP 2023551982A5 JP 2023534301 A JP2023534301 A JP 2023534301A JP 2023534301 A JP2023534301 A JP 2023534301A JP 2023551982 A5 JP2023551982 A5 JP 2023551982A5
Authority
JP
Japan
Prior art keywords
protein
sequence encoding
nucleotide sequence
promoter
self
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023534301A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023551982A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/061203 external-priority patent/WO2022118226A1/en
Publication of JP2023551982A publication Critical patent/JP2023551982A/ja
Publication of JP2023551982A5 publication Critical patent/JP2023551982A5/ja
Pending legal-status Critical Current

Links

JP2023534301A 2020-12-02 2021-12-02 マルチシストロン性rnaワクチン及びその使用 Pending JP2023551982A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063120362P 2020-12-02 2020-12-02
US63/120,362 2020-12-02
PCT/IB2021/061203 WO2022118226A1 (en) 2020-12-02 2021-12-02 Multicistronic rna vaccines and uses thereof

Publications (2)

Publication Number Publication Date
JP2023551982A JP2023551982A (ja) 2023-12-13
JP2023551982A5 true JP2023551982A5 (https=) 2024-11-07

Family

ID=81852979

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023534301A Pending JP2023551982A (ja) 2020-12-02 2021-12-02 マルチシストロン性rnaワクチン及びその使用

Country Status (9)

Country Link
US (1) US20240024455A1 (https=)
EP (1) EP4255446A4 (https=)
JP (1) JP2023551982A (https=)
KR (1) KR20230120646A (https=)
CN (1) CN117222415A (https=)
AU (1) AU2021392077A1 (https=)
CA (1) CA3199996A1 (https=)
IL (1) IL303315A (https=)
WO (1) WO2022118226A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL296752A (en) * 2020-04-03 2022-11-01 Gritstone Bio Inc Infectious disease antigens and vaccines
US20240009296A1 (en) * 2022-07-10 2024-01-11 Pfizer Inc. Self-amplifying rna encoding an influenza virus antigen
JP2025528112A (ja) * 2022-08-08 2025-08-26 セキラス インコーポレイテッド Rnaコードウイルス様粒子及びその使用
TW202438672A (zh) * 2023-01-31 2024-10-01 美商亞克圖羅斯醫療公司 四價流感疫苗之方法及組成物
KR20250140103A (ko) * 2023-02-09 2025-09-24 화이자 인코포레이티드 핵산 및 이의 용도
AU2024271830A1 (en) * 2023-05-12 2025-11-27 Seqirus Inc. Vaccine adjuvants
CN119101681A (zh) * 2023-06-09 2024-12-10 仁景(苏州)生物科技有限公司 表达可调控的工程化rna分子
EP4727580A1 (en) * 2023-06-16 2026-04-22 Seqirus Inc. Virus-like particles for the treatment of sars-cov2
WO2025003979A2 (en) * 2023-06-30 2025-01-02 Seqirus Inc. Combination rna vaccine
CN121752291A (zh) * 2023-06-30 2026-03-27 思齐乐私人有限公司 SARS-CoV-2 RNA疫苗及其用途
WO2025177220A1 (en) * 2024-02-21 2025-08-28 Seqirus Inc. Alternative self-amplifying rna
WO2025217136A2 (en) * 2024-04-08 2025-10-16 Amplitude Therapeutics, Inc. Trans-amplifying rnas encoding immunomodulators
WO2025215618A1 (en) * 2024-04-12 2025-10-16 Seqirus Inc. Methods and reagents for treating or preventing ebv
WO2025230868A1 (en) * 2024-04-29 2025-11-06 Trustees Of Boston University Self-amplifying rna and methods
WO2025257691A1 (en) * 2024-06-10 2025-12-18 Seqirus Inc. Potency assay

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232324A1 (en) * 2001-05-31 2003-12-18 Chiron Corporation Chimeric alphavirus replicon particles
EP2848692B1 (en) * 2004-05-21 2017-08-16 Novartis Vaccines and Diagnostics, Inc. Alphavirus vectors for influenza virus vaccines
CA2766907A1 (en) * 2009-07-06 2011-01-13 Novartis Ag Self replicating rna molecules and uses thereof
MX350258B (es) * 2011-07-06 2017-08-31 Novartis Ag Emulsiones cationicas de aceite en agua.
RU2014118727A (ru) * 2011-10-11 2015-11-20 Новартис Аг Рекомбинантные самореплицирующиеся полицистронные молекулы рнк
EP3015475A1 (en) * 2014-10-31 2016-05-04 Novartis AG Mammalian cells expressing cytomegalovirus antigens
BE1024796B9 (fr) * 2016-06-02 2019-01-08 Glaxosmithkline Biologicals Sa Constructions antigeniques du virus zika
WO2020028612A1 (en) * 2018-08-01 2020-02-06 Massachusetts Institute Of Technology Rna-based regulatory technologies for mirna sensors
US12083174B2 (en) * 2018-08-17 2024-09-10 Glaxosmithkline Biologicals Sa Immunogenic compositions and uses thereof

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