|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
US5436146A
(en)
|
1989-09-07 |
1995-07-25 |
The Trustees Of Princeton University |
Helper-free stocks of recombinant adeno-associated virus vectors
|
|
US6268213B1
(en)
|
1992-06-03 |
2001-07-31 |
Richard Jude Samulski |
Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy
|
|
US5869305A
(en)
|
1992-12-04 |
1999-02-09 |
The University Of Pittsburgh |
Recombinant viral vector system
|
|
EP0682717A4
(en)
|
1993-02-05 |
1997-04-23 |
Laporte Group Australia |
ANTI-FOAMING COMPOSITE FOR DAIRY.
|
|
US5869337A
(en)
|
1993-02-12 |
1999-02-09 |
President And Fellows Of Harvard College |
Regulated transcription of targeted genes and other biological events
|
|
US5834266A
(en)
|
1993-02-12 |
1998-11-10 |
President & Fellows Of Harvard College |
Regulated apoptosis
|
|
US6140120A
(en)
|
1993-02-12 |
2000-10-31 |
Board Of Trustees Of Leland Stanford Jr. University |
Regulated transcription of targeted genes and other biological events
|
|
EP0804561B1
(en)
|
1993-02-12 |
2009-12-30 |
The Board Of Trustees Of The Leland Stanford Junior University |
Regulated transcription of targeted genes and other biological events
|
|
US20020173474A1
(en)
|
1993-02-12 |
2002-11-21 |
President And Fellows Of Harvard College |
Methods & materials involving dimerization-mediated regulation of biological events
|
|
US5830462A
(en)
|
1993-02-12 |
1998-11-03 |
President & Fellows Of Harvard College |
Regulated transcription of targeted genes and other biological events
|
|
US6972193B1
(en)
|
1993-02-12 |
2005-12-06 |
Board Of Trustees Of Leland Stanford Junior University |
Regulated transcription of targeted genes and other biological events
|
|
US6150137A
(en)
|
1994-05-27 |
2000-11-21 |
Ariad Pharmaceuticals, Inc. |
Immunosuppressant target proteins
|
|
US6476200B1
(en)
|
1994-06-27 |
2002-11-05 |
The Johns Hopkins University |
Mammalian proteins that bind to FKBP12 in a rapamycin-dependent fashion
|
|
US6492106B1
(en)
|
1994-06-27 |
2002-12-10 |
The Johns Hopkins University |
Mammalian proteins that bind to FKBP12 in a rapamycin-dependent fashion
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US6150527A
(en)
|
1994-08-18 |
2000-11-21 |
Ariad Pharmaceuticals, Inc. |
Synthetic multimerizing agents
|
|
US6133456A
(en)
|
1994-08-18 |
2000-10-17 |
Ariad Gene Therapeutics, Inc. |
Synthetic multimerizing agents
|
|
DE69534300T2
(de)
|
1994-08-18 |
2006-05-18 |
Ariad Gene Therapeutics, Inc., Cambridge |
Neues multimerisierendes reagenz
|
|
US6326166B1
(en)
|
1995-12-29 |
2001-12-04 |
Massachusetts Institute Of Technology |
Chimeric DNA-binding proteins
|
|
AU719001B2
(en)
|
1994-12-29 |
2000-05-04 |
Massachusetts Institute Of Technology |
Chimeric DNA-binding proteins
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
WO1996041865A1
(en)
|
1995-06-07 |
1996-12-27 |
Ariad Gene Therapeutics, Inc. |
Rapamcycin-based regulation of biological events
|
|
US5811524A
(en)
|
1995-06-07 |
1998-09-22 |
Idec Pharmaceuticals Corporation |
Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US6187757B1
(en)
|
1995-06-07 |
2001-02-13 |
Ariad Pharmaceuticals, Inc. |
Regulation of biological events using novel compounds
|
|
US6506379B1
(en)
|
1995-06-07 |
2003-01-14 |
Ariad Gene Therapeutics, Inc. |
Intramuscular delivery of recombinant AAV
|
|
AU731826B2
(en)
|
1996-02-28 |
2001-04-05 |
Ariad Pharmaceuticals, Inc. |
Synthetic Multimerizing Agents
|
|
US6723531B2
(en)
|
1996-04-05 |
2004-04-20 |
The Salk Institute For Biological Studies |
Method for modulating expression of exogenous genes in mammalian systems, and products related thereto
|
|
AU735648B2
(en)
|
1996-07-12 |
2001-07-12 |
Ariad Pharmaceuticals, Inc. |
Materials and method for treating or preventing pathogenic fungal infection
|
|
US6548286B1
(en)
|
1997-04-14 |
2003-04-15 |
Cell Genesys, Inc. |
Methods for increasing the efficiency of recombinant AAV product
|
|
US6015709A
(en)
|
1997-08-26 |
2000-01-18 |
Ariad Pharmaceuticals, Inc. |
Transcriptional activators, and compositions and uses related thereto
|
|
JP2003524368A
(ja)
|
1997-08-26 |
2003-08-19 |
アリアド ジーン セラピューティクス インコーポレイテッド |
ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、ｄｎａ結合ドメインまたはリガンド結合ドメインを含む融合蛋白
|
|
US6479653B1
(en)
|
1997-08-26 |
2002-11-12 |
Ariad Gene Therapeutics, Inc. |
Compositions and method for regulation of transcription
|
|
JP2001514007A
(ja)
|
1997-08-27 |
2001-09-11 |
アリアド ジーン セラピューティクス インコーポレイテッド |
キメラ転写アクチベーター、ならびにそれに関連する組成物および使用
|
|
JP2002508971A
(ja)
|
1998-01-15 |
2002-03-26 |
アリアド・ジーン・セラピューティクス・インコーポレーテッド |
多量体キメラ蛋白質を使用する生物学的イベントの調節
|
|
US6984635B1
(en)
|
1998-02-13 |
2006-01-10 |
Board Of Trustees Of The Leland Stanford Jr. University |
Dimerizing agents, their production and use
|
|
JP2002503667A
(ja)
|
1998-02-13 |
2002-02-05 |
プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ |
新規な二量体化剤、その製造および使用
|
|
US6333318B1
(en)
|
1998-05-14 |
2001-12-25 |
The Salk Institute For Biological Studies |
Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
|
|
US6146874A
(en)
|
1998-05-27 |
2000-11-14 |
University Of Florida |
Method of preparing recombinant adeno-associated virus compositions
|
|
US6258603B1
(en)
|
1998-06-17 |
2001-07-10 |
Rohm And Haas Company |
Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
|
|
US7109317B1
(en)
|
1998-11-06 |
2006-09-19 |
President And Fellows Of Harvard College |
FK506-based regulation of biological events
|
|
AU780231B2
(en)
|
1998-11-10 |
2005-03-10 |
University Of North Carolina At Chapel Hill, The |
Virus vectors and methods of making and administering the same
|
|
CA2379166C
(en)
|
1999-08-09 |
2013-03-26 |
Targeted Genetics Corporation |
Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms instrastrand base pairs
|
|
ATE264863T1
(de)
|
1999-08-24 |
2004-05-15 |
Ariad Gene Therapeutics Inc |
28-epirapaloge
|
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
|
AU2001249315A1
(en)
|
2000-03-22 |
2001-10-03 |
Rheogene, Inc. |
Ecdysone receptor-based inducible gene expression system
|
|
US20040033600A1
(en)
|
2001-03-21 |
2004-02-19 |
Palli Subba Reddy |
Ecdysone receptor-based inducible gene expression system
|
|
US7201898B2
(en)
|
2000-06-01 |
2007-04-10 |
The University Of North Carolina At Chapel Hill |
Methods and compounds for controlled release of recombinant parvovirus vectors
|
|
US8105825B2
(en)
|
2000-10-03 |
2012-01-31 |
Intrexon Corporation |
Multiple inducible gene regulation system
|
|
EP1373470B1
(en)
|
2001-02-20 |
2013-04-24 |
Intrexon Corporation |
Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
|
|
WO2002066614A2
(en)
|
2001-02-20 |
2002-08-29 |
Rheogene Holdings, Inc. |
Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system
|
|
EP1534738B1
(en)
|
2001-02-20 |
2012-06-20 |
Intrexon Corporation |
Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
|
|
JP4955904B2
(ja)
|
2001-02-20 |
2012-06-20 |
イントレキソン コーポレーション |
新規エクジソン受容体／無脊椎動物レチノイドｘ受容体−ベースの誘導性遺伝子発現システム
|
|
MX359371B
(es)
|
2001-11-13 |
2018-09-25 |
Univ Pennsylvania |
Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo.
|
|
PT1453547T
(pt)
|
2001-12-17 |
2016-12-28 |
Univ Pennsylvania |
Sequências do vírus adeno-associado (aav) do serotipo 8, vetores contendo as mesmas, e utilizações destas
|
|
AU2003274397A1
(en)
|
2002-06-05 |
2003-12-22 |
University Of Florida |
Production of pseudotyped recombinant aav virions
|
|
EP2345731B1
(en)
|
2003-09-30 |
2015-10-21 |
The Trustees of the University of Pennsylvania |
Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
|
|
US20060246079A1
(en)
|
2003-11-14 |
2006-11-02 |
Morrow Phillip R |
Neutralizing human antibodies to anthrax toxin
|
|
US7935510B2
(en)
|
2004-04-30 |
2011-05-03 |
Intrexon Corporation |
Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
|
|
ES2525067T3
(es)
|
2005-04-07 |
2014-12-17 |
The Trustees Of The University Of Pennsylvania |
Método de incremento de la función de un vector de AAV
|
|
JP4495210B2
(ja)
|
2005-06-09 |
2010-06-30 |
パナソニック株式会社 |
振幅誤差補償装置及び直交度誤差補償装置
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
US7879326B2
(en)
|
2007-06-15 |
2011-02-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Human neutralizing monoclonal antibodies to H5N1 influenza A virus
|
|
ITTO20080204A1
(it)
|
2008-03-17 |
2009-09-18 |
Pomona Biotechnologies Llc |
Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a
|
|
ITTO20080398A1
(it)
|
2008-05-27 |
2009-11-28 |
Pomona Biotechnologies Llc |
Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
|
|
CA2731686C
(en)
|
2008-07-25 |
2020-04-07 |
Institute For Research In Biomedicine |
Neutralizing anti-influenza a virus antibodies and uses thereof
|
|
GB0813784D0
(en)
|
2008-07-28 |
2008-09-03 |
Ct Integrated Photonics Ltd |
Optical intergration system
|
|
EP3269395A1
(en)
|
2008-11-07 |
2018-01-17 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
CA2761648C
(en)
|
2009-05-11 |
2019-03-12 |
Crucell Holland B.V. |
Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof
|
|
US8734809B2
(en)
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
|
EP2435575A2
(en)
*
|
2009-05-28 |
2012-04-04 |
Deutsches Krebsforschungszentrum |
Modified aav capsid polypeptides
|
|
IT1395961B1
(it)
|
2009-06-01 |
2012-11-02 |
Pomona Biotechnologies Llc |
Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv)
|
|
WO2011126808A2
(en)
|
2010-03-29 |
2011-10-13 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
US20130037977A1
(en)
|
2010-04-08 |
2013-02-14 |
Paul A. Burke |
Preparation of Lipid Nanoparticles
|
|
US8927514B2
(en)
|
2010-04-30 |
2015-01-06 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
|
US8853377B2
(en)
|
2010-11-30 |
2014-10-07 |
Shire Human Genetic Therapies, Inc. |
mRNA for use in treatment of human genetic diseases
|
|
WO2012145572A1
(en)
|
2011-04-20 |
2012-10-26 |
The Trustees Of The University Of Pennsylvania |
Regimens and compositions for aav-mediated passive immunization of airborne pathogens
|
|
HRP20180291T1
(hr)
|
2011-05-27 |
2018-03-23 |
Amicus Therapeutics, Inc. |
Postupci za sparivanje ciljajućeg peptida na rekombinantne lizosomalne enzime za poboljšano liječenje lizosomskih bolesti nakupljanja
|
|
RU2013154295A
(ru)
|
2011-06-08 |
2015-07-20 |
Шир Хьюман Дженетик Терапис, Инк. |
КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК
|
|
FR2977562B1
(fr)
|
2011-07-06 |
2016-12-23 |
Gaztransport Et Technigaz |
Cuve etanche et thermiquement isolante integree dans une structure porteuse
|
|
US20150126589A1
(en)
|
2012-06-08 |
2015-05-07 |
Ethris Gmbh |
Pulmonary Delivery of Messenger RNA
|
|
EP4331620A3
(en)
|
2012-12-07 |
2024-12-04 |
Translate Bio, Inc. |
Lipidic nanoparticles for mrna delivery
|
|
AU2014228231B2
(en)
|
2013-03-15 |
2019-02-21 |
Amicus Therapeutics, Inc. |
Chemical crosslinkers
|
|
AU2014348212C1
(en)
|
2013-11-18 |
2018-11-29 |
Arcturus Therapeutics, Inc. |
Ionizable cationic lipid for RNA delivery
|
|
EP3134431B1
(en)
|
2014-04-25 |
2021-04-07 |
The Trustees Of The University Of Pennsylvania |
Ldlr variants and their use in compositions for reducing cholesterol levels
|
|
AU2015320694B2
(en)
|
2014-09-24 |
2021-11-11 |
City Of Hope |
Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
|
|
EP3237605B1
(en)
*
|
2014-12-24 |
2021-02-24 |
Neuorphan Pty Ltd. |
Improvements in oligodendroglial cell culturing methods and in methods for treating neurodegenerative disorders by using thyroid hormones or analogues
|
|
EA201792500A1
(ru)
|
2015-05-13 |
2018-04-30 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Aav-опосредованная экспрессия антител против гриппа и способы их использования
|
|
KR102423442B1
(ko)
|
2015-12-11 |
2022-07-20 |
캘리포니아 인스티튜트 오브 테크놀로지 |
아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드
|
|
PT3589730T
(pt)
|
2017-02-28 |
2024-02-28 |
Univ Pennsylvania |
Vetor de vírus adenoassociado (aav) de clado f e suas utilizações
|
|
UY37620A
(es)
|
2017-02-28 |
2018-08-31 |
Univ Pennsylvania |
Vacunas contra la gripe mediadas por aav novedosas
|
|
EP3609542B1
(en)
*
|
2017-04-11 |
2023-02-22 |
Ruprecht-Karls-Universität Heidelberg |
Adeno-associated virus library
|
|
IL276859B2
(en)
|
2018-02-27 |
2025-12-01 |
Univ Pennsylvania |
Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor
|
|
WO2020160582A1
(de)
|
2019-02-04 |
2020-08-13 |
Technische Universität Wien |
Tübbing aus bewehrtem beton
|
|
EP3947700A4
(en)
*
|
2019-04-01 |
2023-01-04 |
Tenaya Therapeutics, Inc. |
Adeno-associated virus with engineered capsid
|
|
SG11202111375RA
(en)
|
2019-04-29 |
2021-11-29 |
Univ Pennsylvania |
Novel aav capsids and compositions containing same
|