JP2023550626A5 - - Google Patents

Info

Publication number
JP2023550626A5
JP2023550626A5 JP2023530765A JP2023530765A JP2023550626A5 JP 2023550626 A5 JP2023550626 A5 JP 2023550626A5 JP 2023530765 A JP2023530765 A JP 2023530765A JP 2023530765 A JP2023530765 A JP 2023530765A JP 2023550626 A5 JP2023550626 A5 JP 2023550626A5
Authority
JP
Japan
Prior art keywords
tgf
polypeptide
masked
sequence
polypeptide sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023530765A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023550626A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/060357 external-priority patent/WO2022109399A1/en
Publication of JP2023550626A publication Critical patent/JP2023550626A/ja
Publication of JP2023550626A5 publication Critical patent/JP2023550626A5/ja
Pending legal-status Critical Current

Links

JP2023530765A 2020-11-23 2021-11-22 TGF-βポリペプチド Pending JP2023550626A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063117307P 2020-11-23 2020-11-23
US63/117,307 2020-11-23
US202163177935P 2021-04-21 2021-04-21
US63/177,935 2021-04-21
US202163195673P 2021-06-01 2021-06-01
US63/195,673 2021-06-01
US202163250990P 2021-09-30 2021-09-30
US63/250,990 2021-09-30
PCT/US2021/060357 WO2022109399A1 (en) 2020-11-23 2021-11-22 Tgf-beta polypeptides

Publications (2)

Publication Number Publication Date
JP2023550626A JP2023550626A (ja) 2023-12-04
JP2023550626A5 true JP2023550626A5 (enExample) 2025-01-07

Family

ID=81709765

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023530765A Pending JP2023550626A (ja) 2020-11-23 2021-11-22 TGF-βポリペプチド

Country Status (5)

Country Link
US (1) US20230416321A1 (enExample)
EP (1) EP4247431A4 (enExample)
JP (1) JP2023550626A (enExample)
CA (1) CA3174130A1 (enExample)
WO (1) WO2022109399A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250151519A (ko) * 2023-02-20 2025-10-21 아케소 바이오파마 컴퍼니 리미티드 TGF-βRII 세포 외 영역 단편을 포함하는 융합 단백질, 및 이의 약제학적 조성물, 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110165623A1 (en) * 2004-01-06 2011-07-07 The Government Of The U.S. As Represented By The Secretary, Dept. Of Health & Human Services Compositions and Methods for the High Efficiency Expression of the Transforming Growth Factor-Beta Supergene Family
AU2010215761B2 (en) * 2009-02-23 2017-04-06 Cytomx Therapeutics, Inc Proproteins and methods of use thereof
JP5841845B2 (ja) * 2009-02-24 2016-01-13 ソーク・インステチュート・フォー・バイオロジカル・スタディーズSalk Institute For Biological Studies TGF−βスーパーファミリーのデザイナーリガンド
ES2948647T3 (es) * 2017-05-04 2023-09-15 Acceleron Pharma Inc Proteínas de fusión del receptor TGF-beta tipo II y usos de las mismas
US20220002370A1 (en) * 2018-09-27 2022-01-06 Xilio Development, Inc. Masked cytokine polypeptides

Similar Documents

Publication Publication Date Title
JP7227290B2 (ja) キメラ抗原受容体、組成物及び方法
JP7597836B2 (ja) 骨標的抗体
JP7627517B2 (ja) 抗cd73抗体、抗体薬物複合体、及びその使用
JP7421338B2 (ja) 免疫調節融合タンパク質
JP2021512899A5 (enExample)
US5767260A (en) Antigen-binding fusion proteins
EP1071468B1 (en) Enhancement of antibody-cytokine fusion protein mediated immune responses by co-administration with angiogenesis inhibitor
JP2020143115A (ja) 片頭痛の治療または予防法
JP2019137675A5 (enExample)
CN112040985A (zh) 用于递送治疗性蛋白质的方法和组合物
JP2016105714A (ja) 代替軽鎖の発現
CA2328081A1 (en) Enhancement of antibody-cytokine fusion protein mediated immune responses by co-administration with prostaglandin inhibitor
CA3152776A1 (en) Pharmaceutical formulations and dosage regimens for multi-specific binding proteins that bind her2, nkg2d, and cd16 for cancer treatment
CN106573966A (zh) 用于治疗代谢异常的组合物和方法
JP7702445B2 (ja) 免疫調節融合タンパク質
RU2007119989A (ru) Композиции, слитые конструкции и конъюгаты plad домена
CA3073560A1 (en) Anti-egfr antibody drug conjugates (adc) and uses thereof
JP2023537292A (ja) SIRPα-Fc融合タンパク質
JP2021518132A (ja) Gipr抗体及びglp−1とのその融合タンパク質、並びにその医薬組成物及び用途
JP2023550626A5 (enExample)
JP2022513321A5 (enExample)
CA3073331A1 (en) Anti-egfr antibody drug conjugates (adc) and uses thereof
JP7239987B2 (ja) 薬物送達のための抗体融合タンパク質
US20220257729A1 (en) Combination of integrin-targeting knottin-fc fusion and anti-cd47 antibody for the treatment of cancer
WO2020221136A1 (zh) 一种蛋白质异二聚体及其用途