JP2023550444A5 - - Google Patents

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Publication number
JP2023550444A5
JP2023550444A5 JP2023530323A JP2023530323A JP2023550444A5 JP 2023550444 A5 JP2023550444 A5 JP 2023550444A5 JP 2023530323 A JP2023530323 A JP 2023530323A JP 2023530323 A JP2023530323 A JP 2023530323A JP 2023550444 A5 JP2023550444 A5 JP 2023550444A5
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Japan
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general formula
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JP2023530323A
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Japanese (ja)
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JP7849587B2 (ja
JP2023550444A (ja
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Priority claimed from PCT/CN2021/131642 external-priority patent/WO2022105852A1/zh
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JP2023530323A 2020-11-20 2021-11-19 トリアジンジオン系誘導体、その調製方法及びその医薬的応用 Active JP7849587B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CN202011310827 2020-11-20
CN202011310827.4 2020-11-20
CN202110021509 2021-01-08
CN202110021509.4 2021-01-08
CN202110244090.9 2021-03-05
CN202110244090 2021-03-05
CN202110464375.3 2021-04-28
CN202110464375 2021-04-28
PCT/CN2021/131642 WO2022105852A1 (zh) 2020-11-20 2021-11-19 三嗪二酮类衍生物、其制备方法及其在医药上的应用

Publications (3)

Publication Number Publication Date
JP2023550444A JP2023550444A (ja) 2023-12-01
JP2023550444A5 true JP2023550444A5 (https=) 2024-05-23
JP7849587B2 JP7849587B2 (ja) 2026-04-22

Family

ID=81708401

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023530323A Active JP7849587B2 (ja) 2020-11-20 2021-11-19 トリアジンジオン系誘導体、その調製方法及びその医薬的応用

Country Status (10)

Country Link
US (1) US20240010639A1 (https=)
EP (1) EP4249474A4 (https=)
JP (1) JP7849587B2 (https=)
KR (1) KR20230110538A (https=)
CN (4) CN119638682A (https=)
AU (1) AU2021381664A1 (https=)
CA (1) CA3198934A1 (https=)
MX (1) MX2023005533A (https=)
TW (1) TW202227420A (https=)
WO (1) WO2022105852A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA53491A (fr) 2018-08-31 2021-09-15 Cytokinetics Inc Inhibiteurs de sarcomes cardiaques
CN117083275A (zh) 2021-03-04 2023-11-17 赛特凯恩蒂克公司 心脏肌节抑制剂
CA3211730A1 (en) * 2021-03-17 2022-09-22 Hugh Y. Zhu Nitrogen-containing heterocyclic ketones, preparation methods and medicinal uses thereof
PT4370116T (pt) 2021-07-16 2025-03-14 Cytokinetics Inc Regimes de administração de aficamten para o tratamento da cardiomiopatia hipertrófica obstrutiva
CN117088854A (zh) * 2022-05-20 2023-11-21 江苏恒瑞医药股份有限公司 一种三嗪二酮类衍生物的可药用盐、晶型及制备方法
CN119053591A (zh) * 2022-05-20 2024-11-29 江苏恒瑞医药股份有限公司 一种三嗪二酮类衍生物的晶型及制备方法
WO2024056096A1 (zh) * 2022-09-16 2024-03-21 江苏豪森药业集团有限公司 一种含氮杂环酮化合物的晶型及其制备方法

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
WO2010040661A1 (en) 2008-10-09 2010-04-15 F. Hoffmann-La Roche Ag Modulators for amyloid beta
PL2399910T3 (pl) * 2009-02-13 2014-09-30 Shionogi & Co Pochodne triazyny jako antagoniści receptora p2x3 i/albo p2x2/3 i kompozycja farmaceutyczna zawierająca je
WO2012006004A1 (en) * 2010-06-28 2012-01-12 Janssen Pharmaceutica Nv Prokineticin 1 receptor antagonists for the treatment of pain
CN103153968B (zh) 2010-08-10 2016-02-03 盐野义制药株式会社 三唑衍生物及含有其的具有镇痛作用的药物组合物
SMT202000071T1 (it) * 2013-06-21 2020-03-13 Myokardia Inc Composti di pirimidinadione contro le condizioni cardiache
US9199945B2 (en) * 2013-06-21 2015-12-01 MyoKardia, Inc. Cycloalkyl-substituted pyrimidinedione compounds
US9663516B2 (en) * 2014-12-18 2017-05-30 MyoKardia, Inc. Bicyclic-pyrimidinedione compounds
ES2975263T3 (es) 2016-06-20 2024-07-04 Novartis Ag Formas cristalinas de un compuesto triazolopirimidínico
RS65492B1 (sr) 2017-07-24 2024-05-31 Novartis Ag Jedinjenja i kompozicije za lečenje stanja povezanih sa aktivnošću nlrp
CA3071948A1 (en) 2017-08-04 2019-02-07 MyoKardia, Inc. Mavacamten for use in the treatment of hypertrophic cardiomyopathy
CN111094300B (zh) * 2018-01-31 2022-09-16 江苏恒瑞医药股份有限公司 苯并杂芳基类衍生物、其制备方法及其在医药上的应用
MA53491A (fr) * 2018-08-31 2021-09-15 Cytokinetics Inc Inhibiteurs de sarcomes cardiaques
EA202191152A1 (ru) 2018-10-29 2022-01-19 Миокардиа, Инк. Тетрагидропиран (thp)-замещенные бициклические соединения пиримидиндиона
CN111116492B (zh) * 2019-01-25 2021-07-09 青岛吉澳医药科技有限公司 氘代苯甲氨嘧啶二酮衍生物及其用途
CN110698415B (zh) 2019-10-21 2023-05-09 上海先行医药开发有限公司 一种肌球蛋白抑制剂及其制备方法和用途
CA3211730A1 (en) * 2021-03-17 2022-09-22 Hugh Y. Zhu Nitrogen-containing heterocyclic ketones, preparation methods and medicinal uses thereof

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