JP2022534902A5 - - Google Patents
Info
- Publication number
- JP2022534902A5 JP2022534902A5 JP2021570180A JP2021570180A JP2022534902A5 JP 2022534902 A5 JP2022534902 A5 JP 2022534902A5 JP 2021570180 A JP2021570180 A JP 2021570180A JP 2021570180 A JP2021570180 A JP 2021570180A JP 2022534902 A5 JP2022534902 A5 JP 2022534902A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- groups
- ring
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025010128A JP2025066800A (ja) | 2019-05-31 | 2025-01-23 | Ｂａｘ阻害剤およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962855185P | 2019-05-31 | 2019-05-31 | |
| US62/855,185 | 2019-05-31 | ||
| PCT/US2020/035564 WO2021002986A2 (en) | 2019-05-31 | 2020-06-01 | Bax inhibitors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025010128A Division JP2025066800A (ja) | 2019-05-31 | 2025-01-23 | Ｂａｘ阻害剤およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022534902A JP2022534902A (ja) | 2022-08-04 |
| JP2022534902A5 true JP2022534902A5 (https=) | 2023-06-08 |
| JP7675020B2 JP7675020B2 (ja) | 2025-05-12 |
Family
ID=74100581
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021570180A Active JP7675020B2 (ja) | 2019-05-31 | 2020-06-01 | Ｂａｘ阻害剤およびその使用 |
| JP2025010128A Pending JP2025066800A (ja) | 2019-05-31 | 2025-01-23 | Ｂａｘ阻害剤およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025010128A Pending JP2025066800A (ja) | 2019-05-31 | 2025-01-23 | Ｂａｘ阻害剤およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12479857B2 (https=) |
| EP (1) | EP3976009A4 (https=) |
| JP (2) | JP7675020B2 (https=) |
| AU (1) | AU2020299526B2 (https=) |
| CA (1) | CA3142424A1 (https=) |
| WO (1) | WO2021002986A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020299526B2 (en) | 2019-05-31 | 2026-01-29 | Case Western Reserve University | Bax inhibitors and uses thereof |
| EP4479383A4 (en) * | 2022-02-17 | 2026-01-07 | Sunnybrook Res Inst | ISOQUINOLINE DERIVATIVES USED AS BAX AND/OR BAK INHIBITORS, COMPOSITIONS AND ASSOCIATED USES |
| KR102896033B1 (ko) * | 2022-12-22 | 2025-12-04 | 연세대학교 산학협력단 | N-벤질퀴나졸린-4-아민 화합물을 포함하는, 비만 및 지질 관련 대사성 질환의 예방 또는 치료용 조성물 |
| WO2024208292A1 (zh) * | 2023-04-04 | 2024-10-10 | 江苏亚虹医药科技股份有限公司 | 泛素特异性蛋白酶1抑制剂、其制备方法及其医药用途 |
| CN120882721A (zh) * | 2023-07-28 | 2025-10-31 | 双翼原创（上海）医药有限公司 | Arf1抑制剂及其应用 |
| CN120554372A (zh) * | 2024-02-27 | 2025-08-29 | 浙江养生堂天然药物研究所有限公司 | 嘧啶并杂芳类化合物及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4798824A (en) | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| US4879283A (en) | 1985-10-03 | 1989-11-07 | Wisconsin Alumni Research Foundation | Solution for the preservation of organs |
| RU2025973C1 (ru) | 1992-02-10 | 1995-01-09 | Научно-производственное предприятие "Биофарм" | Раствор для консервации живых органов |
| US5552267A (en) | 1992-04-03 | 1996-09-03 | The Trustees Of Columbia University In The City Of New York | Solution for prolonged organ preservation |
| US5370989A (en) | 1992-04-03 | 1994-12-06 | The Trustees Of Columbia University In The City Of New York | Solution for prolonged organ preservation |
| AU664074B2 (en) | 1992-06-26 | 1995-11-02 | Torii Pharmaceutical Co., Ltd. | Organ preserving fluid |
| US5405742A (en) | 1993-07-16 | 1995-04-11 | Cyromedical Sciences, Inc. | Solutions for tissue preservation and bloodless surgery and methods using same |
| US6046206A (en) * | 1995-06-07 | 2000-04-04 | Cell Pathways, Inc. | Method of treating a patient having a precancerous lesions with amide quinazoline derivatives |
| US6969720B2 (en) | 1999-03-17 | 2005-11-29 | Amr Technology, Inc. | Biaryl substituted purine derivatives as potent antiproliferative agents |
| EP1125925A1 (en) | 2000-02-15 | 2001-08-22 | Applied Research Systems ARS Holding N.V. | Amine derivatives for the treatment of apoptosis |
| GB0220187D0 (en) | 2002-08-30 | 2002-10-09 | Novartis Ag | Organic compounds |
| WO2012079079A1 (en) | 2010-12-10 | 2012-06-14 | President And Fellows Of Harvard College | Production of induced pluripotent stem cells |
| WO2014005186A1 (en) | 2012-07-06 | 2014-01-09 | Newsouth Innovations Pty Limited | Methods for inhibiting neuron apoptosis and necrosis |
| EP2938610A2 (en) | 2012-12-28 | 2015-11-04 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Inhibitors of the usp1/uaf1 deubiquitinase complex and uses thereof |
| US10519160B2 (en) | 2014-07-18 | 2019-12-31 | The General Hospital Corporation | Imaging agents for neural flux |
| WO2018019284A1 (en) | 2016-07-28 | 2018-02-01 | Realinn Life Science Limited | Compounds for enhancing bax/bcl-2 expression and activity and therapeutic use thereof |
| AU2020299526B2 (en) | 2019-05-31 | 2026-01-29 | Case Western Reserve University | Bax inhibitors and uses thereof |
| JP7674020B1 (ja) * | 2024-07-19 | 2025-05-09 | 株式会社大都技研 | 遊技台 |
-
2020
- 2020-06-01 AU AU2020299526A patent/AU2020299526B2/en active Active
- 2020-06-01 WO PCT/US2020/035564 patent/WO2021002986A2/en not_active Ceased
- 2020-06-01 US US17/615,377 patent/US12479857B2/en active Active
- 2020-06-01 CA CA3142424A patent/CA3142424A1/en active Pending
- 2020-06-01 JP JP2021570180A patent/JP7675020B2/ja active Active
- 2020-06-01 EP EP20835329.2A patent/EP3976009A4/en active Pending
-
2025
- 2025-01-23 JP JP2025010128A patent/JP2025066800A/ja active Pending
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