JP2023550281A - 流体の特に硝子体内投与のための投与デバイス - Google Patents

流体の特に硝子体内投与のための投与デバイス Download PDF

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Publication number
JP2023550281A
JP2023550281A JP2023526214A JP2023526214A JP2023550281A JP 2023550281 A JP2023550281 A JP 2023550281A JP 2023526214 A JP2023526214 A JP 2023526214A JP 2023526214 A JP2023526214 A JP 2023526214A JP 2023550281 A JP2023550281 A JP 2023550281A
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JP
Japan
Prior art keywords
main unit
primer
actuating
dosing
drive spring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023526214A
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English (en)
Japanese (ja)
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JP2023550281A5 (cg-RX-API-DMAC10.html
Inventor
アクセル ロート
オリバー デイヴィッド フォッグ
ポール グラハム ヘイトン
アンドリュー ガイ ラバット－ロシュクスト
アハラーム ジャウダット カッタン
シュテッフェン シューイ
ワトソン ベンジャミン ハリー カリス
Original Assignee
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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Publication of JP2023550281A publication Critical patent/JP2023550281A/ja
Publication of JP2023550281A5 publication Critical patent/JP2023550281A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31571—Means preventing accidental administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
    • A61M5/31578—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the axial movement of a component directly in contact with it
    • A61M5/31581—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the axial movement of a component directly in contact with it the component being manually operated or triggered by a rotating or pivoting actuator operated by user, e.g. an injection lever or handle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5013—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
    • A61M5/502—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston
    • A61M2005/5033—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston by use of an intermediate blocking member positioned between the syringe barrel and the piston rod to prevent retraction of the latter, e.g. toothed clip placed on the piston rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2023526214A 2020-10-30 2021-10-29 流体の特に硝子体内投与のための投与デバイス Pending JP2023550281A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20205001 2020-10-30
EP20205001.9 2020-10-30
PCT/EP2021/080118 WO2022090463A1 (en) 2020-10-30 2021-10-29 Administration device for in particular intravitreal administration of a fluid

Publications (2)

Publication Number Publication Date
JP2023550281A true JP2023550281A (ja) 2023-12-01
JP2023550281A5 JP2023550281A5 (cg-RX-API-DMAC10.html) 2024-11-06

Family

ID=73043100

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023526214A Pending JP2023550281A (ja) 2020-10-30 2021-10-29 流体の特に硝子体内投与のための投与デバイス

Country Status (11)

Country Link
US (1) US20230390109A1 (cg-RX-API-DMAC10.html)
EP (1) EP4237043B1 (cg-RX-API-DMAC10.html)
JP (1) JP2023550281A (cg-RX-API-DMAC10.html)
KR (1) KR20230098171A (cg-RX-API-DMAC10.html)
CN (1) CN116583314A (cg-RX-API-DMAC10.html)
AU (1) AU2021369609A1 (cg-RX-API-DMAC10.html)
CA (1) CA3193701A1 (cg-RX-API-DMAC10.html)
CL (1) CL2023001011A1 (cg-RX-API-DMAC10.html)
MX (1) MX2023004995A (cg-RX-API-DMAC10.html)
TW (1) TWI895534B (cg-RX-API-DMAC10.html)
WO (1) WO2022090463A1 (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD866757S1 (en) * 2016-03-11 2019-11-12 Millennium Pharmaceuticals, Inc. Autoinjector
USD1037439S1 (en) 2022-01-17 2024-07-30 EyePoint Pharamaceuticals, Inc. Ocular injector
CN122161565A (zh) * 2023-11-08 2026-06-05 里珍纳龙药品有限公司 用于眼部组织的药物递送的系统及方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012504437A (ja) * 2008-10-01 2012-02-23 エス・ホー・エル・グループ・アクチボラゲット 渦巻きバネにより駆動する薬剤送達装置
JP2013530024A (ja) * 2010-07-02 2013-07-25 イテロ バイオファーマシューティカルズ インコーポレイテッド 防腐剤非含有卵胞刺激ホルモン溶液供給装置
JP2014028114A (ja) * 2012-07-03 2014-02-13 Novartis Ag 注射器
JP2014507219A (ja) * 2011-02-03 2014-03-27 エス・ホー・エル・グループ・アクチボラゲット 薬剤送達装置
JP2014526369A (ja) * 2011-09-22 2014-10-06 アッヴィ・インコーポレイテッド 自動注入装置
US20160220327A1 (en) * 2015-01-29 2016-08-04 Bryan Tapocik Mechanical pen with improvements for pen removably retaining singleuse capsule containing tooth whitening compounds, dental bonding compounds and adhesives and removably retaining disposable tooth whitening applicators, disposable dental bonding compound applicators and disposable adhesive applicators
US20170087304A1 (en) * 2014-06-05 2017-03-30 Carebay Europe Ltd Medicament delivery device with delivery finish signal delay
US20190001065A1 (en) * 2015-08-19 2019-01-03 Carebay Europe Ltd Variable single dose medicament delivery device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536249A (en) * 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US20060069350A1 (en) 2004-09-30 2006-03-30 Buenger David R Medical syringe injector pen
US20100231102A1 (en) 2009-03-16 2010-09-16 Peter Block Stowable and releasably securable mobile structure
EP3374005B1 (en) * 2015-11-13 2023-08-02 SHL Medical AG Activation mechanism for a medicament delivery device and a medicament delivery device comprising the activation mechanism
US11779708B2 (en) * 2017-12-22 2023-10-10 Sanofi Drug delivery device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012504437A (ja) * 2008-10-01 2012-02-23 エス・ホー・エル・グループ・アクチボラゲット 渦巻きバネにより駆動する薬剤送達装置
JP2013530024A (ja) * 2010-07-02 2013-07-25 イテロ バイオファーマシューティカルズ インコーポレイテッド 防腐剤非含有卵胞刺激ホルモン溶液供給装置
JP2014507219A (ja) * 2011-02-03 2014-03-27 エス・ホー・エル・グループ・アクチボラゲット 薬剤送達装置
JP2014526369A (ja) * 2011-09-22 2014-10-06 アッヴィ・インコーポレイテッド 自動注入装置
JP2014526368A (ja) * 2011-09-22 2014-10-06 アッヴィ・インコーポレイテッド 自動注入装置
JP2014028114A (ja) * 2012-07-03 2014-02-13 Novartis Ag 注射器
US20170087304A1 (en) * 2014-06-05 2017-03-30 Carebay Europe Ltd Medicament delivery device with delivery finish signal delay
US20160220327A1 (en) * 2015-01-29 2016-08-04 Bryan Tapocik Mechanical pen with improvements for pen removably retaining singleuse capsule containing tooth whitening compounds, dental bonding compounds and adhesives and removably retaining disposable tooth whitening applicators, disposable dental bonding compound applicators and disposable adhesive applicators
US20190001065A1 (en) * 2015-08-19 2019-01-03 Carebay Europe Ltd Variable single dose medicament delivery device

Also Published As

Publication number Publication date
TW202233140A (zh) 2022-09-01
EP4237043B1 (en) 2026-02-11
KR20230098171A (ko) 2023-07-03
WO2022090463A1 (en) 2022-05-05
EP4237043A1 (en) 2023-09-06
TWI895534B (zh) 2025-09-01
AU2021369609A1 (en) 2023-06-15
MX2023004995A (es) 2023-05-12
CL2023001011A1 (es) 2023-12-01
CA3193701A1 (en) 2022-05-05
US20230390109A1 (en) 2023-12-07
CN116583314A (zh) 2023-08-11

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