JP2023549124A5 - - Google Patents
Info
- Publication number
- JP2023549124A5 JP2023549124A5 JP2023527351A JP2023527351A JP2023549124A5 JP 2023549124 A5 JP2023549124 A5 JP 2023549124A5 JP 2023527351 A JP2023527351 A JP 2023527351A JP 2023527351 A JP2023527351 A JP 2023527351A JP 2023549124 A5 JP2023549124 A5 JP 2023549124A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- acid sequence
- variant
- capsid polypeptide
- gjb2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063110697P | 2020-11-06 | 2020-11-06 | |
| US63/110,697 | 2020-11-06 | ||
| US202163146269P | 2021-02-05 | 2021-02-05 | |
| US63/146,269 | 2021-02-05 | ||
| PCT/US2021/058255 WO2022099007A1 (en) | 2020-11-06 | 2021-11-05 | Variant adeno-associated virus (aav)capsid polypeptides and gene therapeutics thereof for treatment of hearing loss |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023549124A JP2023549124A (ja) | 2023-11-22 |
| JP2023549124A5 true JP2023549124A5 (enExample) | 2024-10-31 |
Family
ID=81457402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023527351A Pending JP2023549124A (ja) | 2020-11-06 | 2021-11-05 | 難聴の治療のためのバリアントアデノ随伴ウイルス（ａａｖ）カプシドポリペプチド、及びその遺伝子治療薬 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240226330A9 (enExample) |
| JP (1) | JP2023549124A (enExample) |
| KR (1) | KR20230117731A (enExample) |
| AU (1) | AU2021376225A1 (enExample) |
| CA (1) | CA3197592A1 (enExample) |
| IL (1) | IL302653A (enExample) |
| MX (1) | MX2023005344A (enExample) |
| WO (1) | WO2022099007A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL325122A (en) | 2018-02-22 | 2026-02-01 | Akouos Inc | Compositions and methods for treating non-age-related hearing impairment in humans |
| CA3168055A1 (en) | 2020-02-21 | 2021-08-26 | Emmanuel John Simons | Compositions and methods for treating non-age-associated hearing impairment in a human subject |
| CN120187432A (zh) * | 2023-02-10 | 2025-06-20 | 苏州星奥拓维生物技术有限公司 | Gch1抑制剂在制备用于预防和治疗听力损伤的药物中的用途 |
| CN116925239B (zh) * | 2023-07-17 | 2024-10-18 | 苏州星奥拓维生物技术有限公司 | 双载体系统表达Otof基因的组合物和方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10294281B2 (en) * | 2012-05-15 | 2019-05-21 | University Of Florida Research Foundation, Incorporated | High-transduction-efficiency rAAV vectors, compositions, and methods of use |
| WO2019200016A1 (en) * | 2018-04-10 | 2019-10-17 | President And Fellows Of Harvard College | Aav vectors encoding clarin-1 or gjb2 and uses thereof |
| CN113853437A (zh) * | 2018-11-07 | 2021-12-28 | 阿库斯股份有限公司 | 腺相关病毒载体用于在内耳中的毛细胞和支持细胞中校正基因缺陷/表达蛋白质的用途 |
| CN113924109A (zh) * | 2019-01-18 | 2022-01-11 | 巴斯德研究所 | Aav介导的基因疗法恢复耳畸蛋白基因 |
| JP7713130B2 (ja) * | 2019-09-30 | 2025-07-25 | イーライ リリー アンド カンパニー | 遺伝性難聴の処置のためのアデノ随伴ウイルス（ａａｖ）システム |
| CN111349148A (zh) * | 2020-03-13 | 2020-06-30 | 辉大(上海)生物科技有限公司 | 一种腺相关病毒载体及其用途 |
-
2021
- 2021-11-05 MX MX2023005344A patent/MX2023005344A/es unknown
- 2021-11-05 KR KR1020237018930A patent/KR20230117731A/ko active Pending
- 2021-11-05 IL IL302653A patent/IL302653A/en unknown
- 2021-11-05 JP JP2023527351A patent/JP2023549124A/ja active Pending
- 2021-11-05 CA CA3197592A patent/CA3197592A1/en active Pending
- 2021-11-05 WO PCT/US2021/058255 patent/WO2022099007A1/en not_active Ceased
- 2021-11-05 AU AU2021376225A patent/AU2021376225A1/en active Pending
-
2023
- 2023-05-05 US US18/143,902 patent/US20240226330A9/en active Pending
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