|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
NL8200523A
(nl)
|
1982-02-11 |
1983-09-01 |
Univ Leiden |
Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna.
|
|
US4952500A
(en)
|
1988-02-01 |
1990-08-28 |
University Of Georgia Research Foundation, Inc. |
Cloning systems for Rhodococcus and related bacteria
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US5302523A
(en)
|
1989-06-21 |
1994-04-12 |
Zeneca Limited |
Transformation of plant cells
|
|
US5550318A
(en)
|
1990-04-17 |
1996-08-27 |
Dekalb Genetics Corporation |
Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
|
|
US7705215B1
(en)
|
1990-04-17 |
2010-04-27 |
Dekalb Genetics Corporation |
Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
|
|
US5322783A
(en)
|
1989-10-17 |
1994-06-21 |
Pioneer Hi-Bred International, Inc. |
Soybean transformation by microparticle bombardment
|
|
US5484956A
(en)
|
1990-01-22 |
1996-01-16 |
Dekalb Genetics Corporation |
Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
|
|
US5384253A
(en)
|
1990-12-28 |
1995-01-24 |
Dekalb Genetics Corporation |
Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
|
|
WO1993004169A1
(en)
|
1991-08-20 |
1993-03-04 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
|
US5610042A
(en)
|
1991-10-07 |
1997-03-11 |
Ciba-Geigy Corporation |
Methods for stable transformation of wheat
|
|
DE69334225D1
(de)
|
1992-07-07 |
2008-07-31 |
Japan Tobacco Inc |
Verfahren zur transformation einer monokotyledon pflanze
|
|
US5702932A
(en)
|
1992-07-20 |
1997-12-30 |
University Of Florida |
Microinjection methods to transform arthropods with exogenous DNA
|
|
WO1994002620A2
(en)
|
1992-07-27 |
1994-02-03 |
Pioneer Hi-Bred International, Inc. |
An improved method of agrobacterium-mediated transformation of cultured soybean cells
|
|
GB9222888D0
(en)
|
1992-10-30 |
1992-12-16 |
British Tech Group |
Tomography
|
|
US5656610A
(en)
|
1994-06-21 |
1997-08-12 |
University Of Southern California |
Producing a protein in a mammal by injection of a DNA-sequence into the tongue
|
|
US5736524A
(en)
|
1994-11-14 |
1998-04-07 |
Merck & Co.,. Inc. |
Polynucleotide tuberculosis vaccine
|
|
US5780448A
(en)
|
1995-11-07 |
1998-07-14 |
Ottawa Civic Hospital Loeb Research |
DNA-based vaccination of fish
|
|
US5945100A
(en)
|
1996-07-31 |
1999-08-31 |
Fbp Corporation |
Tumor delivery vehicles
|
|
US5981274A
(en)
|
1996-09-18 |
1999-11-09 |
Tyrrell; D. Lorne J. |
Recombinant hepatitis virus vectors
|
|
CA2277278A1
(en)
|
1997-01-10 |
1998-07-16 |
Life Technologies, Inc. |
Embryonic stem cell serum replacement
|
|
JP2001523958A
(ja)
|
1997-03-21 |
2001-11-27 |
ブライハム アンド ウィミンズ ホスピタル，インコーポレイテッド |
免疫療法のｃｔｌａ−４結合ペプチド
|
|
US5994624A
(en)
|
1997-10-20 |
1999-11-30 |
Cotton Incorporated |
In planta method for the production of transgenic plants
|
|
DK1141028T3
(da)
|
1998-12-23 |
2010-05-25 |
Pfizer |
Humane monoklonale antistoffer til CTLA-4
|
|
IL148079A0
(en)
|
1999-08-24 |
2002-09-12 |
Medarex Inc |
Human ctla-4 antibodies and compositions containing the same
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
RU2494107C2
(ru)
|
2005-05-09 |
2013-09-27 |
Оно Фармасьютикал Ко., Лтд. |
Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами
|
|
HRP20131167T1
(hr)
|
2007-06-18 |
2014-01-03 |
Merck Sharp & Dohme B.V. |
Antitijela za humani receptor programirane smrti pd-1
|
|
PT2242773T
(pt)
|
2008-02-11 |
2017-09-15 |
Cure Tech Ltd |
Anticorpos monoclonais para o tratamento de tumores
|
|
WO2009114335A2
(en)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Pd-1 binding proteins
|
|
WO2010014784A2
(en)
|
2008-08-01 |
2010-02-04 |
Bristol-Myers Squibb Company |
Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
|
|
WO2010098788A2
(en)
|
2008-08-25 |
2010-09-02 |
Amplimmune, Inc. |
Pd-i antagonists and methods for treating infectious disease
|
|
WO2011066342A2
(en)
|
2009-11-24 |
2011-06-03 |
Amplimmune, Inc. |
Simultaneous inhibition of pd-l1/pd-l2
|
|
JP2014022858A
(ja)
|
2012-07-17 |
2014-02-03 |
Murata Mfg Co Ltd |
電力増幅器
|
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
|
EA034666B1
(ru)
|
2013-09-13 |
2020-03-04 |
Бейджин Свитзерланд Гмбх |
Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела
|
|
CN106103711A
(zh)
*
|
2013-11-21 |
2016-11-09 |
组库创世纪株式会社 |
T细胞受体和b细胞受体库分析系统及其在治疗和诊断中的应用
|
|
JP6464255B2
(ja)
|
2014-08-04 |
2019-02-06 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性ｔ細胞活性化抗原結合分子
|
|
EP3916018A1
(en)
|
2015-06-16 |
2021-12-01 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
|
AU2017225733A1
(en)
*
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore
|
|
CN110139873A
(zh)
*
|
2016-10-03 |
2019-08-16 |
朱诺治疗学股份有限公司 |
Hpv特异性结合分子
|
|
AU2018318303A1
(en)
*
|
2017-08-18 |
2020-04-09 |
Gritstone Bio, Inc. |
Antigen-binding proteins targeting shared antigens
|
|
US20220175899A1
(en)
*
|
2019-04-11 |
2022-06-09 |
The Board Of Trustees Of The Leland Stanford Junior University |
Cytotoxic t lymphocytes specific for mutated forms of epidermal growth factor receptor for use in treating cancer
|
|
CN111848782A
(zh)
*
|
2019-04-25 |
2020-10-30 |
天津亨佳生物科技发展有限公司 |
一种针对egfr l858r基因突变的特异性t细胞受体及其应用
|
|
EP3962939A4
(en)
*
|
2019-05-03 |
2023-05-17 |
Gigamune, Inc. |
MODIFIED CELLS EXPRESSING ANTITUMOR T-LYMPHOCYTE RECEPTORS AND METHODS OF USING THEM
|