JP2023547441A5 - - Google Patents
Info
- Publication number
- JP2023547441A5 JP2023547441A5 JP2023526007A JP2023526007A JP2023547441A5 JP 2023547441 A5 JP2023547441 A5 JP 2023547441A5 JP 2023526007 A JP2023526007 A JP 2023526007A JP 2023526007 A JP2023526007 A JP 2023526007A JP 2023547441 A5 JP2023547441 A5 JP 2023547441A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrimidine
- compound
- methyl
- nitrooxy
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20205111.6 | 2020-11-02 | ||
| EP20205111 | 2020-11-02 | ||
| PCT/EP2021/079958 WO2022090379A1 (en) | 2020-11-02 | 2021-10-28 | No-pde5 inhibitor for use in treating dry age-related macular degeneration, geographic atrophy and glaucoma-associated neurodegeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023547441A JP2023547441A (ja) | 2023-11-10 |
| JP2023547441A5 true JP2023547441A5 (enExample) | 2024-10-29 |
Family
ID=73043154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023526007A Pending JP2023547441A (ja) | 2020-11-02 | 2021-10-28 | 萎縮型加齢黄斑変性、地図状萎縮および緑内障関連神経変性の処置において使用するためのｎｏ－ｐｄｅ５阻害剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230414621A1 (enExample) |
| EP (1) | EP4236952A1 (enExample) |
| JP (1) | JP2023547441A (enExample) |
| CN (1) | CN116456963A (enExample) |
| WO (1) | WO2022090379A1 (enExample) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL137429A0 (en) | 1999-07-28 | 2001-07-24 | Pfizer Prod Inc | Methods and compsitions for treating diseases and conditions of the eye |
| US20020168424A1 (en) | 2002-07-31 | 2002-11-14 | Dr. Mohsen Shahinpoor | Nitric oxide (NO) donor+cGMP-PDE5 inhibitor as a topical drug for glaucoma |
| CA2986769A1 (en) | 2015-05-27 | 2016-12-01 | Neurotech Usa, Inc. | Use of encapsulated cell therapy for treatment of ophthalmic disorders |
| SMT202200190T1 (it) | 2015-11-16 | 2022-07-21 | Topadur Pharma Ag | Derivati del 2-fenil-3,4-diidropirrolo[2,1-f] [1,2,4]triazinone come inibitori della fosfodesterasi e loro usi |
| US20190152967A1 (en) | 2016-04-04 | 2019-05-23 | The Schepens Eye Research Institute, Inc. | Peroxisome proliferator-activated receptor gamma selective agonists for inhibition of retinal pigment epithelium degeneration or geographic atrophy |
| MX2019013626A (es) | 2017-05-22 | 2020-01-13 | Topadur Pharma Ag | Modo de accion dual novedoso de activadores de guanilato ciclasa solubles e inhibidores de fosfodiesterasa y usos de los mismos. |
| EP3833395A1 (en) * | 2018-08-06 | 2021-06-16 | Nicox S.A. | Nitric oxide releasing phosphodiesterase type 5 inhibitor |
| BR112021009958A2 (pt) * | 2018-11-28 | 2021-08-17 | Topadur Pharma Ag | modo duplo de ação de ativadores de guanilato ciclase solúveis e inibidores de fosfodiesterase e seus usos |
| EP4100014B1 (en) * | 2020-02-05 | 2024-01-03 | Nicox S.A. | Compositions for the treatment of glaucoma and ocular hypertension |
-
2021
- 2021-10-28 WO PCT/EP2021/079958 patent/WO2022090379A1/en not_active Ceased
- 2021-10-28 US US18/251,283 patent/US20230414621A1/en active Pending
- 2021-10-28 JP JP2023526007A patent/JP2023547441A/ja active Pending
- 2021-10-28 CN CN202180074083.7A patent/CN116456963A/zh active Pending
- 2021-10-28 EP EP21805410.4A patent/EP4236952A1/en not_active Withdrawn
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