JP2023546759A5 - - Google Patents

Info

Publication number
JP2023546759A5
JP2023546759A5 JP2023549958A JP2023549958A JP2023546759A5 JP 2023546759 A5 JP2023546759 A5 JP 2023546759A5 JP 2023549958 A JP2023549958 A JP 2023549958A JP 2023549958 A JP2023549958 A JP 2023549958A JP 2023546759 A5 JP2023546759 A5 JP 2023546759A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
acid sequence
sequence described
bifunctional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023549958A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023546759A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/056282 external-priority patent/WO2022087435A1/en
Publication of JP2023546759A publication Critical patent/JP2023546759A/ja
Publication of JP2023546759A5 publication Critical patent/JP2023546759A5/ja
Pending legal-status Critical Current

Links

JP2023549958A 2020-10-23 2021-10-22 腫瘍壊死因子-アルファおよびトランスフォーミング増殖因子-ベータの二機能性アンタゴニストならびにその使用 Pending JP2023546759A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063104850P 2020-10-23 2020-10-23
US63/104,850 2020-10-23
PCT/US2021/056282 WO2022087435A1 (en) 2020-10-23 2021-10-22 Bifunctional antagonists of tumor necrosis factor-alpha and transforming growth factor-beta and uses thereof

Publications (2)

Publication Number Publication Date
JP2023546759A JP2023546759A (ja) 2023-11-07
JP2023546759A5 true JP2023546759A5 (https=) 2024-10-29

Family

ID=81290113

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023549958A Pending JP2023546759A (ja) 2020-10-23 2021-10-22 腫瘍壊死因子-アルファおよびトランスフォーミング増殖因子-ベータの二機能性アンタゴニストならびにその使用

Country Status (9)

Country Link
US (1) US20230391892A1 (https=)
EP (1) EP4232063A4 (https=)
JP (1) JP2023546759A (https=)
KR (1) KR20230112629A (https=)
CN (1) CN116744959A (https=)
AU (1) AU2021365528A1 (https=)
CA (1) CA3196077A1 (https=)
MX (1) MX2023004725A (https=)
WO (1) WO2022087435A1 (https=)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE469176T1 (de) * 2001-11-12 2010-06-15 Merck Patent Gmbh Modifizierter anti-tnf antikörper
NZ590667A (en) * 2008-07-02 2013-01-25 Emergent Product Dev Seattle Tgf-b antagonist multi-target binding proteins
CA3253628A1 (en) * 2010-03-05 2025-11-29 The Johns Hopkins University Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
CN103732623B (zh) * 2011-06-03 2017-09-29 佐马技术有限公司 对TGF‑β具有特异性的抗体
TWI476001B (zh) * 2011-12-26 2015-03-11 Ind Tech Res Inst 三倍體Fc融合蛋白及其用途
HRP20181939T4 (hr) * 2013-03-20 2022-05-13 Genzyme Corporation Postupci za liječenje osteogenesis imperfecta
US10633423B2 (en) * 2014-06-13 2020-04-28 Affibody Ab IL-6-binding polypeptide complex
MX364040B (es) * 2016-11-11 2019-04-11 Cell Therapy And Tech S A De C V Uso farmacéutico de una composición que contiene pirfenidona de liberación prolongada (pfd-lp) para la reversión y tratamiento de la esteatohepatitis humana (nafld/nash).
MX2020009272A (es) * 2018-03-06 2021-01-08 Univ Pennsylvania Receptores de antígeno quimérico del antígeno de membrana específico de próstata y métodos de uso de los mismos.
GB201903767D0 (en) * 2019-03-19 2019-05-01 Quadrucept Bio Ltd Multimers, tetramers & octamers

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