JP2023546369A5 - - Google Patents

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Publication number
JP2023546369A5
JP2023546369A5 JP2023521602A JP2023521602A JP2023546369A5 JP 2023546369 A5 JP2023546369 A5 JP 2023546369A5 JP 2023521602 A JP2023521602 A JP 2023521602A JP 2023521602 A JP2023521602 A JP 2023521602A JP 2023546369 A5 JP2023546369 A5 JP 2023546369A5
Authority
JP
Japan
Prior art keywords
solvate
hydrate
salt
optionally substituted
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023521602A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023546369A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/054318 external-priority patent/WO2022076922A1/en
Publication of JP2023546369A publication Critical patent/JP2023546369A/ja
Publication of JP2023546369A5 publication Critical patent/JP2023546369A5/ja
Pending legal-status Critical Current

Links

JP2023521602A 2020-10-09 2021-10-08 Ｎ－アセチルガラクトサミン（ＧａｌＮＡｃ）から誘導された化合物およびオリゴヌクレオチド Pending JP2023546369A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US202063089936P 2020-10-09 2020-10-09
US63/089,936 2020-10-09
US202063113801P 2020-11-13 2020-11-13
US63/113,801 2020-11-13
US202063131317P 2020-12-29 2020-12-29
US63/131,317 2020-12-29
US202163141300P 2021-01-25 2021-01-25
US63/141,300 2021-01-25
US202163146276P 2021-02-05 2021-02-05
US63/146,276 2021-02-05
US202163251580P 2021-10-01 2021-10-01
US63/251,580 2021-10-01
PCT/US2021/054318 WO2022076922A1 (en) 2020-10-09 2021-10-08 N-ACETYLGALACTOSAMINE(GAlNAc)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES

Publications (2)

Publication Number Publication Date
JP2023546369A JP2023546369A (ja) 2023-11-02
JP2023546369A5 true JP2023546369A5 (https=) 2024-10-16

Family

ID=81126164

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023521602A Pending JP2023546369A (ja) 2020-10-09 2021-10-08 Ｎ－アセチルガラクトサミン（ＧａｌＮＡｃ）から誘導された化合物およびオリゴヌクレオチド

Country Status (10)

Country Link
US (1) US20240083934A1 (https=)
EP (1) EP4225322A4 (https=)
JP (1) JP2023546369A (https=)
KR (1) KR20230113285A (https=)
CN (2) CN121108223A (https=)
AU (1) AU2021359017A1 (https=)
CA (1) CA3198406A1 (https=)
IL (1) IL302000A (https=)
MX (1) MX2023004170A (https=)
WO (1) WO2022076922A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11649260B2 (en) 2021-06-18 2023-05-16 Hongene Biotech Corporation Functionalized N-acetylgalactosamine nucleosides
EP4396193A4 (en) 2021-08-30 2025-07-02 Hongene Biotech Corp FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGUES
JP2024546585A (ja) 2021-12-15 2024-12-26 ホンジーン バイオテック コーポレイション 官能基化ｎ－アセチルガラクトサミンアナログ
JP2025517196A (ja) * 2022-05-13 2025-06-03 エーダーエックス ファーマシューティカルズ， インコーポレイテッド 合成骨格を有するオリゴヌクレオチド及びその合成
WO2024118503A1 (en) 2022-11-28 2024-06-06 Hongene Biotech Corporation Functionalized n-acetylgalactosamine analogs
CN119019354B (zh) * 2023-05-24 2025-07-22 北京炫景瑞医药科技有限公司 化合物及其制备方法和用途
WO2024240101A1 (zh) * 2023-05-24 2024-11-28 北京炫景瑞医药科技有限公司 GalNAc化合物、缀合物、组合物以及它们的用途
CN119019475B (zh) * 2023-05-24 2026-02-06 北京炫景瑞医药科技有限公司 GalNAc化合物、缀合物、组合物以及它们的用途
WO2025140434A1 (zh) * 2023-12-26 2025-07-03 成都倍特药业股份有限公司 一种肝靶向化合物及其在药物缀合物中的用途
CN121263426A (zh) * 2024-05-09 2026-01-02 石药集团中奇制药技术（石家庄）有限公司 GalNAc衍生物及其寡聚核苷酸缀合物
CN118638166B (zh) 2024-08-15 2024-12-17 北京悦康科创医药科技股份有限公司 含有三氮唑结构的GalNAc化合物及其寡核苷酸缀合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472378B2 (en) * 1998-08-31 2002-10-29 Pro-Neuron, Inc. Compositions and methods for treatment of mitochondrial diseases
US6852485B1 (en) * 2002-01-22 2005-02-08 California State University Fullerton Foundation Method for identifying a compound for the treatment of microorganism infections by inhibiting energy storage and utilization in pathogens
AU2009298802A1 (en) * 2008-09-23 2010-04-08 Alnylam Pharmaceuticals, Inc. Chemical modifications of monomers and oligonucleotides with cycloaddition
CN111808084A (zh) * 2008-11-10 2020-10-23 阿布特斯生物制药公司 用于递送治疗剂的新型脂质和组合物
GB201408623D0 (en) * 2014-05-15 2014-07-02 Santaris Pharma As Oligomers and oligomer conjugates
KR20180031025A (ko) * 2015-07-31 2018-03-27 아크투루스 쎄라퓨틱스, 인크. 약물 전달을 위한 다중 리간드 제제
CA3020585A1 (en) * 2016-04-11 2017-10-19 Arbutus Biopharma Corporation Targeted nucleic acid conjugate compositions

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